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CAI

Caris Life Sciences

138 hedge funds and large institutions have $3.41B invested in Caris Life Sciences in 2025 Q3 according to their latest regulatory filings, with 53 funds opening new positions, 45 increasing their positions, 19 reducing their positions, and 31 closing their positions.

New
Increased
Maintained
Reduced
Closed

649% more call options, than puts

Call options by funds: $12.3M | Put options by funds: $1.65M

137% more repeat investments, than reductions

Existing positions increased: 45 | Existing positions reduced: 19

71% more first-time investments, than exits

New positions opened: 53 | Existing positions closed: 31

19% more funds holding

Funds holding: 116138 (+22)

17% more capital invested

Capital invested by funds: $2.92B → $3.41B (+$488M)

1.77% more ownership

Funds ownership: 38.56%40.33% (+1.8%)

17% less funds holding in top 10

Funds holding in top 10: 65 (-1)

Holders
138
Holders Change
+22
Holders Change %
+18.97%
% of All Funds
1.81%
Holding in Top 10
5
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-16.67%
% of All Funds
0.07%
New
53
Increased
45
Reduced
19
Closed
31
Calls
$12.3M
Puts
$1.65M
Net Calls
+$10.7M
Net Calls Change
+$12.7M
Name Holding Trade Value Shares
Change
Change in
Stake
SSP
1
Sixth Street Partners
Texas
$738M
Coatue Management
2
Coatue Management
New York
$307M
Fidelity Investments
3
Fidelity Investments
Massachusetts
$291M +$31.9M +1,001,890 +12%
T. Rowe Price Investment Management
4
T. Rowe Price Investment Management
Maryland
$243M +$23M +721,772 +10%
B
5
Braidwell
Connecticut
$221M
T. Rowe Price Associates
6
T. Rowe Price Associates
Maryland
$209M +$5.23M +163,941 +2%
SLG
7
Silver Lake Group
California
$160M
Millennium Management
8
Millennium Management
New York
$119M +$13.5M +424,896 +12%
PC
9
PointState Capital
New York
$117M +$44.2M +1,385,364 +55%
Neuberger Berman Group
10
Neuberger Berman Group
New York
$109M -$60.4M -1,894,478 -30%
O
11
OrbiMed
New York
$91.8M
Ameriprise
12
Ameriprise
Minnesota
$50.8M +$1.71M +53,754 +3%
Morgan Stanley
13
Morgan Stanley
New York
$46.4M +$23.3M +729,183 +91%
ClearBridge Investments
14
ClearBridge Investments
New York
$41.8M +$3.96M +124,105 +10%
Canada Pension Plan Investment Board
15
Canada Pension Plan Investment Board
Ontario, Canada
$40M
LP
16
Longaeva Partners
Illinois
$38.9M -$5.54M -173,777 -12%
AllianceBernstein
17
AllianceBernstein
Tennessee
$36.4M +$8.43M +264,434 +28%
UBS AM
18
UBS AM
Illinois
$33.8M +$10.1M +316,078 +40%
Alyeska Investment Group
19
Alyeska Investment Group
Illinois
$33.3M +$23.1M +725,071 +193%
PA
20
Perceptive Advisors
New York
$33.2M
GCM
21
Ghisallo Capital Management
Massachusetts
$31.7M
Massachusetts Financial Services
22
Massachusetts Financial Services
Massachusetts
$29.4M -$2.5M -78,398 -7%
JP Morgan Chase
23
JP Morgan Chase
New York
$26M -$2.44M -76,528 -8%
Lord, Abbett & Co
24
Lord, Abbett & Co
New Jersey
$25.7M +$27.1M +850,000 New
Invesco
25
Invesco
Georgia
$24.3M +$9.47M +297,065 +59%

CAI Hedge Fund Activity: Q3 2025 in Review

138 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Caris Life Sciences (CAI) for Q3 2025, worth a combined $3.41B — up 17% from $2.92B a quarter earlier.

Buyers outnumbered sellers: 53 funds opened new CAI positions and 31 closed out — a net gain of 22 holders — while 45 added to existing stakes and 19 trimmed.

The largest buyer was PointState Capital, adding an estimated $44.2M. The largest seller was Neuberger Berman Group, cutting an estimated $60.4M.

  • 138 institutional investors held Caris Life Sciences (CAI) as of Q3 2025, up from 116 in Q2 2025.
  • Funds reported $3.41B of Caris Life Sciences stock for Q3 2025, up 17% quarter-over-quarter.
  • 53 funds opened new Caris Life Sciences positions in Q3 2025 and 31 closed out, a net change of +22 holders.
  • The largest Caris Life Sciences buyer in Q3 2025 was PointState Capital, an estimated $44.2M added.
  • The largest Caris Life Sciences seller in Q3 2025 was Neuberger Berman Group, an estimated $60.4M sold.

Based on aggregated 13F filings for Q3 2025.