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CAI

Caris Life Sciences

138 hedge funds and large institutions have $3.41B invested in Caris Life Sciences in 2025 Q3 according to their latest regulatory filings, with 53 funds opening new positions, 45 increasing their positions, 19 reducing their positions, and 31 closing their positions.

New
Increased
Maintained
Reduced
Closed

649% more call options, than puts

Call options by funds: $12.3M | Put options by funds: $1.65M

137% more repeat investments, than reductions

Existing positions increased: 45 | Existing positions reduced: 19

71% more first-time investments, than exits

New positions opened: 53 | Existing positions closed: 31

19% more funds holding

Funds holding: 116138 (+22)

17% more capital invested

Capital invested by funds: $2.92B → $3.41B (+$488M)

1.77% more ownership

Funds ownership: 38.56%40.33% (+1.8%)

17% less funds holding in top 10

Funds holding in top 10: 65 (-1)

Holders
138
Holders Change
+22
Holders Change %
+18.97%
% of All Funds
1.81%
Holding in Top 10
5
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-16.67%
% of All Funds
0.07%
New
53
Increased
45
Reduced
19
Closed
31
Calls
$12.3M
Puts
$1.65M
Net Calls
+$10.7M
Net Calls Change
+$12.7M
Name Holding Trade Value Shares
Change
Change in
Stake
BBHC
126
Brown Brothers Harriman & Co
New York
$10.4K +$11K +344 New
AAP
127
Arax Advisory Partners
Colorado
$6.57K +$6.31K +198 +1,042%
CIAM
128
Caitong International Asset Management
Hong Kong
$6.29K +$6.63K +208 New
NA
129
NewEdge Advisors
Louisiana
$6.05K
OWP
130
ORG Wealth Partners
Texas
$6.05K
Jones Financial Companies
131
Jones Financial Companies
Missouri
$4.09K +$4.46K +140 New
FMP
132
Financial Management Professionals
Texas
$2.15K +$1.63K +51 +255%
TRCT
133
Tower Research Capital (TRC)
New York
$696 -$66.5K -2,085 -99%
JSAM
134
J. Safra Asset Management
New York
$635 +$670 +21 New
CMA
135
Cedar Mountain Advisors
Oregon
$151
MPWT
136
MassMutual Private Wealth & Trust
Connecticut
$151 +$159 +5 New
GRP
137
Global Retirement Partners
California
$30 +$32 +1 New
TIM
138
Tortoise Investment Management
New York
$30 +$32 +1 New
Capital World Investors
139
Capital World Investors
California
-$26.7M -999,945 Closed
Norges Bank
140
Norges Bank
Norway
-$10M -375,000 Closed
Citadel Advisors
141
Citadel Advisors
Florida
-$10.9M -341,570 Closed
SPPAM
142
Summit Partners Public Asset Management
Massachusetts
-$7.91M -296,000 Closed
Adage Capital Partners
143
Adage Capital Partners
Massachusetts
-$4.01M -150,000 Closed
Aberdeen Group
144
Aberdeen Group
United Kingdom
-$3.15M -117,841 Closed
HF
145
HRT Financial
New York
-$2.92M -109,318 Closed
Blackstone Inc
146
Blackstone Inc
New York
-$2.67M -100,000 Closed
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
147
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
-$2.67M -100,000 Closed
JG
148
Jain Global
New York
-$2.33M -87,288 Closed
LIA
149
Limestone Investment Advisors
New York
-$2.3M -86,000 Closed
HFA
150
Harbert Fund Advisors
Alabama
-$2.14M -80,000 Closed

CAI Hedge Fund Activity: Q3 2025 in Review

138 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Caris Life Sciences (CAI) for Q3 2025, worth a combined $3.41B — up 17% from $2.92B a quarter earlier.

Buyers outnumbered sellers: 53 funds opened new CAI positions and 31 closed out — a net gain of 22 holders — while 45 added to existing stakes and 19 trimmed.

The largest buyer was PointState Capital, adding an estimated $44.2M. The largest seller was Neuberger Berman Group, cutting an estimated $60.4M.

  • 138 institutional investors held Caris Life Sciences (CAI) as of Q3 2025, up from 116 in Q2 2025.
  • Funds reported $3.41B of Caris Life Sciences stock for Q3 2025, up 17% quarter-over-quarter.
  • 53 funds opened new Caris Life Sciences positions in Q3 2025 and 31 closed out, a net change of +22 holders.
  • The largest Caris Life Sciences buyer in Q3 2025 was PointState Capital, an estimated $44.2M added.
  • The largest Caris Life Sciences seller in Q3 2025 was Neuberger Berman Group, an estimated $60.4M sold.

Based on aggregated 13F filings for Q3 2025.