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CAI

Caris Life Sciences

138 hedge funds and large institutions have $3.41B invested in Caris Life Sciences in 2025 Q3 according to their latest regulatory filings, with 53 funds opening new positions, 45 increasing their positions, 19 reducing their positions, and 31 closing their positions.

New
Increased
Maintained
Reduced
Closed

649% more call options, than puts

Call options by funds: $12.3M | Put options by funds: $1.65M

137% more repeat investments, than reductions

Existing positions increased: 45 | Existing positions reduced: 19

71% more first-time investments, than exits

New positions opened: 53 | Existing positions closed: 31

19% more funds holding

Funds holding: 116138 (+22)

17% more capital invested

Capital invested by funds: $2.92B → $3.41B (+$488M)

1.77% more ownership

Funds ownership: 38.56%40.33% (+1.8%)

17% less funds holding in top 10

Funds holding in top 10: 65 (-1)

Holders
138
Holders Change
+22
Holders Change %
+18.97%
% of All Funds
1.81%
Holding in Top 10
5
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-16.67%
% of All Funds
0.07%
New
53
Increased
45
Reduced
19
Closed
31
Calls
$12.3M
Puts
$1.65M
Net Calls
+$10.7M
Net Calls Change
+$12.7M
Name Holding Trade Value Shares
Change
Change in
Stake
Ohio Public Employees Retirement System (OPERS)
101
Ohio Public Employees Retirement System (OPERS)
Ohio
$212K +$223K +6,997 New
Balyasny Asset Management
102
Balyasny Asset Management
Illinois
$209K -$1.39M -43,453 -86%
American Century Companies
103
American Century Companies
Missouri
$208K +$219K +6,865 New
SC
104
SummitTX Capital
Texas
$204K +$215K +6,736 New
WAP
105
Wealthcare Advisory Partners
Pennsylvania
$202K +$213K +6,666 New
PMAM
106
Picton Mahoney Asset Management
Ontario, Canada
$188K +$198K +6,210 New
Royal Bank of Canada
107
Royal Bank of Canada
Ontario, Canada
$130K +$111K +3,470 +423%
Simplex Trading
108
Simplex Trading
Illinois
$120K +$100K +3,151 +379%
Barclays
109
Barclays
United Kingdom
$96.1K -$218K -6,823 -68%
Legal & General Group
110
Legal & General Group
United Kingdom
$69.4K +$41.4K +1,297 +130%
Russell Investments Group
111
Russell Investments Group
United Kingdom
$60.3K +$63.6K +1,995 New
Wells Fargo
112
Wells Fargo
California
$53.5K +$15K +470 +36%
AB
113
Amalgamated Bank
New York
$44K +$46.7K +1,463 New
California State Teachers Retirement System (CalSTRS)
114
California State Teachers Retirement System (CalSTRS)
California
$39.5K +$41.6K +1,306 New
SS
115
SBI Securities
Japan
$37.1K +$34.1K +1,068 +676%
BNP Paribas Financial Markets
116
BNP Paribas Financial Markets
France
$36.3K +$38.3K +1,200 New
BF
117
BOK Financial
Oklahoma
$34.2K +$36.1K +1,131 New
MIM
118
MetLife Investment Management
New Jersey
$27.2K +$28.7K +899 New
PNC Financial Services Group
119
PNC Financial Services Group
Pennsylvania
$25.9K +$20.9K +655 +328%
Carson Wealth (CWM LLC)
120
Carson Wealth (CWM LLC)
Nebraska
$24K +$20K +628 +419%
SCM
121
Sterling Capital Management
North Carolina
$21.6K +$22.8K +714 New
Comerica Bank
122
Comerica Bank
Texas
$20K +$21.1K +662 New
Nomura Asset Management
123
Nomura Asset Management
Japan
$17K
Osaic Holdings
124
Osaic Holdings
Arizona
$16.9K -$17.5K -550 -55%
SO
125
STRS Ohio
Ohio
$16.2K +$17.1K +536 New

CAI Hedge Fund Activity: Q3 2025 in Review

138 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Caris Life Sciences (CAI) for Q3 2025, worth a combined $3.41B — up 17% from $2.92B a quarter earlier.

Buyers outnumbered sellers: 53 funds opened new CAI positions and 31 closed out — a net gain of 22 holders — while 45 added to existing stakes and 19 trimmed.

The largest buyer was PointState Capital, adding an estimated $44.2M. The largest seller was Neuberger Berman Group, cutting an estimated $60.4M.

  • 138 institutional investors held Caris Life Sciences (CAI) as of Q3 2025, up from 116 in Q2 2025.
  • Funds reported $3.41B of Caris Life Sciences stock for Q3 2025, up 17% quarter-over-quarter.
  • 53 funds opened new Caris Life Sciences positions in Q3 2025 and 31 closed out, a net change of +22 holders.
  • The largest Caris Life Sciences buyer in Q3 2025 was PointState Capital, an estimated $44.2M added.
  • The largest Caris Life Sciences seller in Q3 2025 was Neuberger Berman Group, an estimated $60.4M sold.

Based on aggregated 13F filings for Q3 2025.