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CAI

Caris Life Sciences

186 hedge funds and large institutions have $3.92B invested in Caris Life Sciences in 2025 Q4 according to their latest regulatory filings, with 77 funds opening new positions, 63 increasing their positions, 30 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

185% more first-time investments, than exits

New positions opened: 77 | Existing positions closed: 27

184% more call options, than puts

Call options by funds: $14.4M | Put options by funds: $5.09M

110% more repeat investments, than reductions

Existing positions increased: 63 | Existing positions reduced: 30

40% more funds holding in top 10

Funds holding in top 10: 57 (+2)

35% more funds holding

Funds holding: 138186 (+48)

15% more capital invested

Capital invested by funds: $3.41B → $3.92B (+$507M)

11.18% more ownership

Funds ownership: 40.33%51.5% (+11%)

Holders
186
Holders Change
+48
Holders Change %
+34.78%
% of All Funds
2.26%
Holding in Top 10
7
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+40%
% of All Funds
0.09%
New
77
Increased
63
Reduced
30
Closed
27
Calls
$14.4M
Puts
$5.09M
Net Calls
+$9.35M
Net Calls Change
-$1.32M
Name Holding Trade Value Shares
Change
Change in
Stake
CM
76
Caption Management
Oklahoma
$1.37M +$1.43M +50,888 New
Bank of New York Mellon
77
Bank of New York Mellon
New York
$1.36M +$719K +25,534 +103%
ECM
78
Element Capital Management
New York
$1.35M +$1.41M +50,000 New
CUAMC
79
China Universal Asset Management Company
China
$1.24M +$1.29M +45,976 New
MP
80
Mangrove Partners
Connecticut
$1.15M +$1.2M +42,483 New
VC
81
VarCov Co
Connecticut
$1.08M +$1.13M +40,037 New
MS
82
Maven Securities
Jersey
$1.08M +$1.13M +40,000 New
Northern Trust
83
Northern Trust
Illinois
$997K -$244K -8,647 -19%
Voloridge Investment Management
84
Voloridge Investment Management
Florida
$946K +$987K +35,050 New
Vanguard Group
85
Vanguard Group
Pennsylvania
$904K -$4M -142,039 -81%
Envestnet Asset Management
86
Envestnet Asset Management
Illinois
$837K +$874K +31,029 New
Citigroup
87
Citigroup
New York
$829K -$499K -17,720 -37%
Mirae Asset Global ETFs Holdings
88
Mirae Asset Global ETFs Holdings
Hong Kong
$814K +$849K +30,157 New
Bessemer Group
89
Bessemer Group
New Jersey
$719K +$751K +26,670 New
Group One Trading
90
Group One Trading
Illinois
$711K +$742K +26,343 New
LPL Financial
91
LPL Financial
California
$694K +$274K +9,720 +61%
Deutsche Bank
92
Deutsche Bank
Germany
$682K
PEAK6
93
PEAK6
Illinois
$669K +$698K +24,800 New
SEI Investments
94
SEI Investments
Pennsylvania
$660K +$689K +24,451 New
SIM
95
Sandia Investment Management
Massachusetts
$637K +$422K +15,000 +174%
RhumbLine Advisers
96
RhumbLine Advisers
Massachusetts
$631K +$53.1K +1,884 +9%
W
97
WPWealth
Texas
$621K -$310 -11 -0%
N
98
Nuveen
North Carolina
$605K
PP
99
PDT Partners
New York
$594K +$620K +22,016 New
ORI
100
Oak Ridge Investments
Illinois
$589K +$615K +21,820 New