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CAI

Caris Life Sciences

138 hedge funds and large institutions have $3.41B invested in Caris Life Sciences in 2025 Q3 according to their latest regulatory filings, with 53 funds opening new positions, 45 increasing their positions, 19 reducing their positions, and 31 closing their positions.

New
Increased
Maintained
Reduced
Closed

649% more call options, than puts

Call options by funds: $12.3M | Put options by funds: $1.65M

137% more repeat investments, than reductions

Existing positions increased: 45 | Existing positions reduced: 19

71% more first-time investments, than exits

New positions opened: 53 | Existing positions closed: 31

19% more funds holding

Funds holding: 116138 (+22)

17% more capital invested

Capital invested by funds: $2.92B → $3.41B (+$488M)

1.77% more ownership

Funds ownership: 38.56%40.33% (+1.8%)

17% less funds holding in top 10

Funds holding in top 10: 65 (-1)

Holders
138
Holders Change
+22
Holders Change %
+18.97%
% of All Funds
1.81%
Holding in Top 10
5
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-16.67%
% of All Funds
0.07%
New
53
Increased
45
Reduced
19
Closed
31
Calls
$12.3M
Puts
$1.65M
Net Calls
+$10.7M
Net Calls Change
+$12.7M
Name Holding Trade Value Shares
Change
Change in
Stake
Bank of New York Mellon
76
Bank of New York Mellon
New York
$752K +$793K +24,869 New
W
77
WPWealth
Texas
$697K +$735K +23,036 New
N
78
Nuveen
North Carolina
$678K +$715K +22,413 New
EGM
79
Engineers Gate Manager
New York
$666K +$702K +22,028 New
RhumbLine Advisers
80
RhumbLine Advisers
Massachusetts
$650K +$686K +21,497 New
PAS
81
Park Avenue Securities
New York
$627K +$661K +20,730 New
MA
82
MSA Advisors
California
$581K
IC
83
IEQ Capital
California
$519K +$547K +17,141 New
Man Group
84
Man Group
United Kingdom
$486K +$513K +16,078 New
LPL Financial
85
LPL Financial
California
$484K +$217K +6,799 +74%
HIA
86
Harbor Investment Advisory
Maryland
$473K +$499K +15,650 New
Jane Street
87
Jane Street
New York
$441K +$465K +14,595 New
US Bancorp
88
US Bancorp
Minnesota
$385K +$27.2K +854 +7%
AP
89
Americana Partners
Texas
$376K +$396K +12,433 New
TWM
90
Triton Wealth Management
Arizona
$327K
PCP
91
Perbak Capital Partners
United Kingdom
$324K +$341K +10,703 New
CM
92
CastleKnight Management
New York
$316K -$3.28M -102,994 -91%
PFSRSONJ
93
Police & Firemen's Retirement System of New Jersey
New Jersey
$314K +$331K +10,372 New
WorldQuant Millennium Advisors
94
WorldQuant Millennium Advisors
New York
$305K +$322K +10,092 New
Treasurer of the State of North Carolina
95
Treasurer of the State of North Carolina
North Carolina
$305K +$321K +10,073 New
BG
96
Bellevue Group
Switzerland
$291K -$12.6K -395 -4%
SIM
97
Sandia Investment Management
Massachusetts
$260K -$44.6K -1,400 -14%
IEFM
98
IQ EQ Fund Management
Ireland
$252K +$266K +8,326 New
OAC
99
OMERS Administration Corp
Ontario, Canada
$248K +$261K +8,200 New
EDRH
100
Edmond de Rothschild Holding
Switzerland
$227K +$239K +7,500 New

CAI Hedge Fund Activity: Q3 2025 in Review

138 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Caris Life Sciences (CAI) for Q3 2025, worth a combined $3.41B — up 17% from $2.92B a quarter earlier.

Buyers outnumbered sellers: 53 funds opened new CAI positions and 31 closed out — a net gain of 22 holders — while 45 added to existing stakes and 19 trimmed.

The largest buyer was PointState Capital, adding an estimated $44.2M. The largest seller was Neuberger Berman Group, cutting an estimated $60.4M.

  • 138 institutional investors held Caris Life Sciences (CAI) as of Q3 2025, up from 116 in Q2 2025.
  • Funds reported $3.41B of Caris Life Sciences stock for Q3 2025, up 17% quarter-over-quarter.
  • 53 funds opened new Caris Life Sciences positions in Q3 2025 and 31 closed out, a net change of +22 holders.
  • The largest Caris Life Sciences buyer in Q3 2025 was PointState Capital, an estimated $44.2M added.
  • The largest Caris Life Sciences seller in Q3 2025 was Neuberger Berman Group, an estimated $60.4M sold.

Based on aggregated 13F filings for Q3 2025.