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CAI

Caris Life Sciences

186 hedge funds and large institutions have $3.92B invested in Caris Life Sciences in 2025 Q4 according to their latest regulatory filings, with 77 funds opening new positions, 63 increasing their positions, 30 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

185% more first-time investments, than exits

New positions opened: 77 | Existing positions closed: 27

184% more call options, than puts

Call options by funds: $14.4M | Put options by funds: $5.09M

110% more repeat investments, than reductions

Existing positions increased: 63 | Existing positions reduced: 30

40% more funds holding in top 10

Funds holding in top 10: 57 (+2)

35% more funds holding

Funds holding: 138186 (+48)

15% more capital invested

Capital invested by funds: $3.41B → $3.92B (+$507M)

11.18% more ownership

Funds ownership: 40.33%51.5% (+11%)

Holders
186
Holders Change
+48
Holders Change %
+34.78%
% of All Funds
2.26%
Holding in Top 10
7
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+40%
% of All Funds
0.09%
New
77
Increased
63
Reduced
30
Closed
27
Calls
$14.4M
Puts
$5.09M
Net Calls
+$9.35M
Net Calls Change
-$1.32M
Name Holding Trade Value Shares
Change
Change in
Stake
Tudor Investment Corp
51
Tudor Investment Corp
Connecticut
$4.92M -$2.31M -82,169 -31%
Jane Street
52
Jane Street
New York
$4.61M +$4.4M +156,402 +1,072%
Walleye Capital
53
Walleye Capital
New York
$4.4M -$4.44M -157,754 -49%
OBAM
54
ODDO BHF Asset Management
France
$4.38M +$4.57M +162,313 New
State of Wisconsin Investment Board
55
State of Wisconsin Investment Board
Wisconsin
$4.05M
Creative Planning
56
Creative Planning
Kansas
$4.04M +$4.22M +149,856 New
PHP
57
Parkman Healthcare Partners
Connecticut
$3.37M +$3.52M +125,000 New
HF
58
HRT Financial
New York
$3.32M +$3.46M +122,939 New
Norges Bank
59
Norges Bank
Norway
$2.98M +$3.11M +110,294 New
JF
60
Jump Financial
Illinois
$2.78M +$2.9M +103,005 New
Manulife (Manufacturers Life Insurance)
61
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$2.78M -$233K -8,268 -8%
Raymond James Financial
62
Raymond James Financial
Florida
$2.63M +$74.1K +2,630 +3%
TWC
63
TD Waterhouse Canada
Ontario, Canada
$2.5M +$2.61M +92,653 New
PVI
64
Pura Vida Investments
New York
$2.43M
TI
65
Trexquant Investment
Connecticut
$2.23M +$2.33M +82,705 New
DFCM
66
Dark Forest Capital Management
Puerto Rico
$2.11M +$1.31M +46,506 +147%
Sumitomo Mitsui Trust Group
67
Sumitomo Mitsui Trust Group
Japan
$2.03M +$444K +15,778 +26%
BGM
68
Burkehill Global Management
New York
$2.02M
EGM
69
Engineers Gate Manager
New York
$1.93M +$1.39M +49,375 +224%
GAM
70
Gotham Asset Management
New York
$1.81M +$957K +33,983 +102%
QCM
71
Quantinno Capital Management
New York
$1.75M -$206K -7,301 -10%
Squarepoint
72
Squarepoint
New York
$1.74M +$1.81M +64,397 New
HLA
73
Hamilton Lane Advisors
Pennsylvania
$1.58M +$1.65M +58,725 New
NAMA
74
Nikko Asset Management Americas
New York
$1.48M +$207K +7,348 +16%
Barclays
75
Barclays
United Kingdom
$1.46M +$1.43M +50,940 +1,603%