We are live on ! Find out more
CAI

Caris Life Sciences
CAI

138 hedge funds and large institutions have $3.41B invested in Caris Life Sciences in 2025 Q3 according to their latest regulatory filings, with 53 funds opening new positions, 45 increasing their positions, 19 reducing their positions, and 31 closing their positions.

New
Increased
Maintained
Reduced
Closed

649% more call options, than puts

Call options by funds: $12.3M | Put options by funds: $1.65M

137% more repeat investments, than reductions

Existing positions increased: 45 | Existing positions reduced: 19

71% more first-time investments, than exits

New positions opened: 53 | Existing positions closed: 31

19% more funds holding

Funds holding: 116 → 138 (+22)

17% more capital invested

Capital invested by funds: $2.92B → $3.41B (+$488M)

1.77% more ownership

Funds ownership: 38.56% → 40.33% (+1.8%)

17% less funds holding in top 10

Funds holding in top 10: 6 → 5 (-1)

Holders
138
Holders Change
+22
Holders Change %
+18.97%
% of All Funds
1.81%
Holding in Top 10
5
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-16.67%
% of All Funds
0.07%
New
53
Increased
45
Reduced
19
Closed
31
Calls
$12.3M
Puts
$1.65M
Net Calls
+$10.7M
Net Calls Change
+$12.7M

Top Buyers

Rank Fund Capital Flow
1
PC
PointState Capital
New York
+$44.2M
2
Fidelity Investments
Fidelity Investments
Massachusetts
+$31.9M
3
Lord, Abbett & Co
Lord, Abbett & Co
New Jersey
+$27.1M
4
Morgan Stanley
Morgan Stanley
New York
+$23.3M
5
Alyeska Investment Group
Alyeska Investment Group
Illinois
+$23.1M

Top Sellers

Rank Fund Capital Flow
1
Neuberger Berman Group
Neuberger Berman Group
New York
-$60.4M
2
Capital World Investors
Capital World Investors
California
-$26.7M
3
WP
Woodline Partners
California
-$16.7M
4
Citadel Advisors
Citadel Advisors
Florida
-$10.9M
5
Franklin Resources
Franklin Resources
California
-$9.89M
Name Holding Trade Value Shares
Change 		Change in
Stake
SGM
51
Seven Grand Managers
New York
$3.02M +$1.59M +50,000 +100%
Raymond James Financial
52
Raymond James Financial
Florida
$2.87M +$2.94M +92,043 +3,235%
RIM
53
Rakuten Investment Management
Japan
$2.79M +$463K +14,518 New
PVI
54
Pura Vida Investments
New York
$2.72M +$1.43M +44,940 +100%
Jennison Associates
55
Jennison Associates
New York
$2.55M -$6.45M -202,165 -71%
Marshall Wace
56
Marshall Wace
United Kingdom
$2.51M +$1.44M +45,102 +119%
BGM
57
Burkehill Global Management
New York
$2.27M – – –
QCM
58
Quantinno Capital Management
New York
$2.18M +$2.3M +72,223 New
CSS
59
Cubist Systematic Strategies
Connecticut
$2.14M +$2.19M +68,731 +3,437%
Sumitomo Mitsui Trust Group
60
Sumitomo Mitsui Trust Group
Japan
$1.8M +$1.51M +47,371 +389%
SFM
61
Soros Fund Management
New York
$1.68M +$180K +5,650 +11%
SIM
62
SRS Investment Management
New York
$1.51M – – –
D.E. Shaw & Co
63
D.E. Shaw & Co
New York
$1.51M +$1.35M +42,285 +564%
Citigroup
64
Citigroup
New York
$1.47M +$1.54M +48,433 +403,608%
NAMA
65
Nikko Asset Management Americas
New York
$1.43M +$1.51M +47,371 New
Northern Trust
66
Northern Trust
Illinois
$1.38M +$1.45M +45,595 New
GAM
67
Gotham Asset Management
New York
$1M +$1.06M +33,203 New
Qube Research & Technologies (QRT)
68
Qube Research & Technologies (QRT)
United Kingdom
$991K +$797K +24,998 +322%
DFCM
69
Dark Forest Capital Management
Puerto Rico
$958K +$1.01M +31,657 New
Verition Fund Management
70
Verition Fund Management
Connecticut
$935K +$986K +30,910 New
Susquehanna International Group
71
Susquehanna International Group
Pennsylvania
$877K +$924K +28,988 New
RC
72
Renaissance Capital
Connecticut
$861K +$908K +28,460 New
XT
73
XTX Topco
Cayman Islands
$849K +$895K +28,081 New
Deutsche Bank
74
Deutsche Bank
Germany
$765K – – –
ACM
75
Atika Capital Management
New York
$756K – – –
1 2
3
4 5

CAI Hedge Fund Activity: Q3 2025 in Review

138 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Caris Life Sciences (CAI) for Q3 2025, worth a combined $3.41B — up 17% from $2.92B a quarter earlier.

Buyers outnumbered sellers: 53 funds opened new CAI positions and 31 closed out — a net gain of 22 holders — while 45 added to existing stakes and 19 trimmed.

The largest buyer was PointState Capital, adding an estimated $44.2M. The largest seller was Neuberger Berman Group, cutting an estimated $60.4M.

  • 138 institutional investors held Caris Life Sciences (CAI) as of Q3 2025, up from 116 in Q2 2025.
  • Funds reported $3.41B of Caris Life Sciences stock for Q3 2025, up 17% quarter-over-quarter.
  • 53 funds opened new Caris Life Sciences positions in Q3 2025 and 31 closed out, a net change of +22 holders.
  • The largest Caris Life Sciences buyer in Q3 2025 was PointState Capital, an estimated $44.2M added.
  • The largest Caris Life Sciences seller in Q3 2025 was Neuberger Berman Group, an estimated $60.4M sold.

Based on aggregated 13F filings for Q3 2025.