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CAI

Caris Life Sciences

186 hedge funds and large institutions have $3.92B invested in Caris Life Sciences in 2025 Q4 according to their latest regulatory filings, with 77 funds opening new positions, 63 increasing their positions, 30 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

185% more first-time investments, than exits

New positions opened: 77 | Existing positions closed: 27

184% more call options, than puts

Call options by funds: $14.4M | Put options by funds: $5.09M

110% more repeat investments, than reductions

Existing positions increased: 63 | Existing positions reduced: 30

40% more funds holding in top 10

Funds holding in top 10: 57 (+2)

35% more funds holding

Funds holding: 138186 (+48)

15% more capital invested

Capital invested by funds: $3.41B → $3.92B (+$507M)

11.18% more ownership

Funds ownership: 40.33%51.5% (+11%)

Holders
186
Holders Change
+48
Holders Change %
+34.78%
% of All Funds
2.26%
Holding in Top 10
7
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+40%
% of All Funds
0.09%
New
77
Increased
63
Reduced
30
Closed
27
Calls
$14.4M
Puts
$5.09M
Net Calls
+$9.35M
Net Calls Change
-$1.32M
Name Holding Trade Value Shares
Change
Change in
Stake
Bank of America
26
Bank of America
North Carolina
$30.3M +$19.5M +693,270 +161%
Invesco
27
Invesco
Georgia
$27.9M +$6.46M +229,313 +29%
Marshall Wace
28
Marshall Wace
United Kingdom
$27.1M +$25.9M +919,759 +1,108%
Massachusetts Financial Services
29
Massachusetts Financial Services
Massachusetts
$25.4M -$836K -29,691 -3%
CIP
30
Champlain Investment Partners
Vermont
$25.3M +$26.5M +939,365 New
GCM
31
Ghisallo Capital Management
Massachusetts
$22.8M -$5.71M -202,831 -19%
TD Asset Management
32
TD Asset Management
Ontario, Canada
$20.9M +$15.5M +551,516 +248%
WP
33
Woodline Partners
California
$19.5M
RSCM
34
Rock Springs Capital Management
Maryland
$18.5M -$2.99M -106,151 -13%
BNP Paribas Financial Markets
35
BNP Paribas Financial Markets
France
$18.5M +$19.3M +684,626 +57,052%
ZCI
36
Zevenbergen Capital Investments
Washington
$14.7M +$15.3M +543,185 New
SGM
37
Seven Grand Managers
New York
$13.4M +$11.1M +395,095 +395%
AIM
38
ARK Investment Management
Florida
$11M +$4.6M +163,375 +67%
Geode Capital Management
39
Geode Capital Management
Massachusetts
$10.1M -$714K -25,349 -6%
Goldman Sachs
40
Goldman Sachs
New York
$9.45M +$1.91M +67,933 +24%
Renaissance Technologies
41
Renaissance Technologies
New York
$8.9M +$2.95M +104,800 +47%
MCP
42
Meridiem Capital Partners
Texas
$7.5M +$7.83M +278,063 New
Franklin Resources
43
Franklin Resources
California
$7.25M +$1.45M +51,651 +24%
State Street
44
State Street
Massachusetts
$7.03M +$2.97M +105,305 +68%
SSA
45
Schonfeld Strategic Advisors
New York
$6.68M +$6.97M +247,407 New
Lazard Asset Management
46
Lazard Asset Management
New York
$6.55M -$979K -34,758 -13%
Holocene Advisors
47
Holocene Advisors
New York
$6.42M +$1.88M +66,770 +39%
PMAM
48
Picton Mahoney Asset Management
Ontario, Canada
$5.89M +$5.97M +212,095 +3,415%
Qube Research & Technologies (QRT)
49
Qube Research & Technologies (QRT)
United Kingdom
$5.58M +$4.91M +174,241 +532%
WorldQuant Millennium Advisors
50
WorldQuant Millennium Advisors
New York
$5.1M +$5.03M +178,769 +1,771%