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CAI

Caris Life Sciences

138 hedge funds and large institutions have $3.41B invested in Caris Life Sciences in 2025 Q3 according to their latest regulatory filings, with 53 funds opening new positions, 45 increasing their positions, 19 reducing their positions, and 31 closing their positions.

New
Increased
Maintained
Reduced
Closed

649% more call options, than puts

Call options by funds: $12.3M | Put options by funds: $1.65M

137% more repeat investments, than reductions

Existing positions increased: 45 | Existing positions reduced: 19

71% more first-time investments, than exits

New positions opened: 53 | Existing positions closed: 31

19% more funds holding

Funds holding: 116138 (+22)

17% more capital invested

Capital invested by funds: $2.92B → $3.41B (+$488M)

1.77% more ownership

Funds ownership: 38.56%40.33% (+1.8%)

17% less funds holding in top 10

Funds holding in top 10: 65 (-1)

Holders
138
Holders Change
+22
Holders Change %
+18.97%
% of All Funds
1.81%
Holding in Top 10
5
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-16.67%
% of All Funds
0.07%
New
53
Increased
45
Reduced
19
Closed
31
Calls
$12.3M
Puts
$1.65M
Net Calls
+$10.7M
Net Calls Change
+$12.7M
Name Holding Trade Value Shares
Change
Change in
Stake
RSCM
26
Rock Springs Capital Management
Maryland
$24M
WP
27
Woodline Partners
California
$21.9M -$16.7M -523,163 -42%
Janus Henderson Group
28
Janus Henderson Group
United Kingdom
$20.1M -$7.18M -225,208 -25%
PD
29
Point72 (DIFC)
United Arab Emirates
$19.8M +$19.2M +600,650 +1,109%
BlackRock
30
BlackRock
New York
$19.6M +$10.8M +337,979 +109%
Bank of America
31
Bank of America
North Carolina
$13M +$12.6M +394,289 +1,120%
Geode Capital Management
32
Geode Capital Management
Massachusetts
$12M +$5.2M +163,094 +69%
FLAM
33
First Light Asset Management
Minnesota
$11.9M -$1.25M -39,119 -9%
Walleye Capital
34
Walleye Capital
New York
$9.7M +$9.02M +282,741 +745%
Goldman Sachs
35
Goldman Sachs
New York
$8.54M +$3.19M +99,956 +55%
Lazard Asset Management
36
Lazard Asset Management
New York
$8.4M +$3.43M +107,608 +63%
Tudor Investment Corp
37
Tudor Investment Corp
Connecticut
$8M
FGP
38
Freestone Grove Partners
California
$7.6M +$6.42M +201,389 +403%
Point72 Asset Management
39
Point72 Asset Management
Connecticut
$7.46M -$6.76M -211,852 -46%
AIM
40
ARK Investment Management
Florida
$7.42M +$6.32M +198,300 +421%
UBS Group
41
UBS Group
Switzerland
$7.14M +$7.52M +235,873 New
Fidelity International
42
Fidelity International
Bermuda
$6.83M -$2.23M -70,051 -24%
Renaissance Technologies
43
Renaissance Technologies
New York
$6.81M +$7.18M +225,100 New
TD Asset Management
44
TD Asset Management
Ontario, Canada
$6.73M +$718K +22,512 +11%
Franklin Resources
45
Franklin Resources
California
$6.56M -$9.89M -310,075 -59%
Vanguard Group
46
Vanguard Group
Pennsylvania
$5.31M +$815K +25,544 +17%
Holocene Advisors
47
Holocene Advisors
New York
$5.18M -$57.9K -1,816 -1%
State Street
48
State Street
Massachusetts
$4.7M +$4.95M +155,340 New
State of Wisconsin Investment Board
49
State of Wisconsin Investment Board
Wisconsin
$4.54M
Manulife (Manufacturers Life Insurance)
50
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$3.33M +$2.79M +87,525 +388%

CAI Hedge Fund Activity: Q3 2025 in Review

138 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Caris Life Sciences (CAI) for Q3 2025, worth a combined $3.41B — up 17% from $2.92B a quarter earlier.

Buyers outnumbered sellers: 53 funds opened new CAI positions and 31 closed out — a net gain of 22 holders — while 45 added to existing stakes and 19 trimmed.

The largest buyer was PointState Capital, adding an estimated $44.2M. The largest seller was Neuberger Berman Group, cutting an estimated $60.4M.

  • 138 institutional investors held Caris Life Sciences (CAI) as of Q3 2025, up from 116 in Q2 2025.
  • Funds reported $3.41B of Caris Life Sciences stock for Q3 2025, up 17% quarter-over-quarter.
  • 53 funds opened new Caris Life Sciences positions in Q3 2025 and 31 closed out, a net change of +22 holders.
  • The largest Caris Life Sciences buyer in Q3 2025 was PointState Capital, an estimated $44.2M added.
  • The largest Caris Life Sciences seller in Q3 2025 was Neuberger Berman Group, an estimated $60.4M sold.

Based on aggregated 13F filings for Q3 2025.