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Cabaletta Bio

108 hedge funds and large institutions have $228M invested in Cabaletta Bio in 2026 Q1 according to their latest regulatory filings, with 27 funds opening new positions, 32 increasing their positions, 27 reducing their positions, and 13 closing their positions.

New
Increased
Maintained
Reduced
Closed

2,362% more call options, than puts

Call options by funds: $9.78M | Put options by funds: $397K

108% more first-time investments, than exits

New positions opened: 27 | Existing positions closed: 13

36% more capital invested

Capital invested by funds: $167M → $228M (+$60.6M)

19% more repeat investments, than reductions

Existing positions increased: 32 | Existing positions reduced: 27

14% more funds holding

Funds holding: 95108 (+13)

3.14% less ownership

Funds ownership: 79.2%76.06% (-3.1%)

Holders
108
Holders Change
+13
Holders Change %
+13.68%
% of All Funds
1.33%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
27
Increased
32
Reduced
27
Closed
13
Calls
$9.78M
Puts
$397K
Net Calls
+$9.38M
Net Calls Change
+$4.57M
Name Holding Trade Value Shares
Change
Change in
Stake
T. Rowe Price Investment Management
1
T. Rowe Price Investment Management
Maryland
$29.8M +$3.39M +1,221,748 +12%
BCLSI
2
Bain Capital Life Sciences Investors
Massachusetts
$26M
Jennison Associates
3
Jennison Associates
New York
$24.1M +$180K +64,879 +0.7%
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$23.8M
Millennium Management
5
Millennium Management
New York
$15.9M +$8.79M +3,166,369 +116%
CAM
6
Cormorant Asset Management
Massachusetts
$14.8M +$3.05M +1,100,000 +25%
VCM
7
Vanguard Capital Management
Pennsylvania
$10.8M +$11.2M +4,028,991 New
Two Sigma Investments
8
Two Sigma Investments
New York
$6.72M +$1.83M +658,118 +36%
BlackRock
9
BlackRock
New York
$6.38M +$124K +44,533 +2%
Marshall Wace
10
Marshall Wace
United Kingdom
$5.86M +$3.39M +1,220,742 +127%
Renaissance Technologies
11
Renaissance Technologies
New York
$5.48M +$1.43M +514,080 +34%
Qube Research & Technologies (QRT)
12
Qube Research & Technologies (QRT)
United Kingdom
$5.21M +$4.45M +1,603,765 +484%
Morgan Stanley
13
Morgan Stanley
New York
$3.79M +$179K +64,444 +5%
OM
14
Opaleye Management
Massachusetts
$3.71M +$1.33M +480,000 +53%
WP
15
Woodline Partners
California
$3.36M
Geode Capital Management
16
Geode Capital Management
Massachusetts
$3.05M +$132K +47,429 +4%
SCM
17
Superstring Capital Management
New York
$2.87M -$3.3M -1,187,311 -53%
IC
18
Ikarian Capital
Texas
$2.42M
Goldman Sachs
19
Goldman Sachs
New York
$2.11M +$979K +352,546 +82%
CF
20
Cantor Fitzgerald
New York
$2.06M +$2.12M +765,000 New
Dimensional Fund Advisors
21
Dimensional Fund Advisors
Texas
$1.99M +$801K +288,609 +64%
BGM
22
Burkehill Global Management
New York
$1.88M
Schroder Investment Management Group
23
Schroder Investment Management Group
United Kingdom
$1.87M
UBS Group
24
UBS Group
Switzerland
$1.63M +$530K +190,987 +46%
VFT
25
Vanguard Fiduciary Trust
Pennsylvania
$1.53M +$1.58M +570,191 New

CABA Hedge Fund Activity: Q1 2026 in Review

108 of the 8,128 institutional investors tracked by Wall St. Rank reported a position in Cabaletta Bio (CABA) for Q1 2026, worth a combined $228M — up 36% from $167M a quarter earlier.

Buyers outnumbered sellers: 27 funds opened new CABA positions and 13 closed out — a net gain of 14 holders — while 32 added to existing stakes and 27 trimmed.

The largest buyer was Millennium Management, adding an estimated $8.79M. The largest seller was Superstring Capital Management, cutting an estimated $3.3M.

  • 108 institutional investors held Cabaletta Bio (CABA) as of Q1 2026, up from 95 in Q4 2025.
  • Funds reported $228M of Cabaletta Bio stock for Q1 2026, up 36% quarter-over-quarter.
  • 27 funds opened new Cabaletta Bio positions in Q1 2026 and 13 closed out, a net change of +14 holders.
  • The largest Cabaletta Bio buyer in Q1 2026 was Millennium Management, an estimated $8.79M added.
  • The largest Cabaletta Bio seller in Q1 2026 was Superstring Capital Management, an estimated $3.3M sold.

Based on aggregated 13F filings for Q1 2026.