Two Sigma Investments
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Two Sigma Investments’s Cabaletta Bio CABA Stock Holding History

Two Sigma Investments’s Portfolio CABA Stock Details CABA Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$6.72M Buy
2,497,917
+658,118
+36% +$1.83M 0.01% 1736
2025
Q4 		$4.03M Buy
1,839,799
+1,369,324
+291% +$3.39M 0.01% 1906
2025
Q3 		$1.1M Buy
470,475
+218,118
+86% +$374K ﹤0.01% 2512
2025
Q2 		$384K Sell
252,357
-69,054
-21% -$108K ﹤0.01% 2691
2025
Q1 		$445K Sell
321,411
-430,483
-57% -$917K ﹤0.01% 2567
2024
Q4 		$1.71M Buy
751,894
+331,417
+79% +$1.16M ﹤0.01% 1822
2024
Q3 		$1.98M Buy
420,477
+25,040
+6% +$145K ﹤0.01% 1686
2024
Q2 		$2.96M Buy
395,437
+358,763
+978% +$4.4M 0.01% 1294
2024
Q1 		$626K Sell
36,674
-38,117
-51% -$818K ﹤0.01% 2226
2023
Q4 		$1.7M Buy
74,791
+28,066
+60% +$472K ﹤0.01% 1725
2023
Q3 		$711K Buy
46,725
+734
+2% +$10K ﹤0.01% 2120
2023
Q2 		$594K Sell
45,991
-38,681
-46% -$420K ﹤0.01% 2253
2023
Q1 		$700K Buy
84,672
+70,372
+492% +$659K ﹤0.01% 2049
2022
Q4 		$132K Sell
14,300
-23,758
-62% -$86.5K ﹤0.01% 2467
2022
Q3 		$25K Sell
38,058
-58,152
-60% -$70K ﹤0.01% 2366
2022
Q2 		$102K Sell
96,210
-53,719
-36% -$76K ﹤0.01% 2267
2022
Q1 		$304K Buy
149,929
+81,362
+119% +$213K ﹤0.01% 2210
2021
Q4 		$260K Sell
68,567
-10,763
-14% -$115K ﹤0.01% 3745
2021
Q3 		$965K Buy
79,330
+66,622
+524% +$614K ﹤0.01% 2648
2021
Q2 		$109K Sell
12,708
-21,093
-62% -$207K ﹤0.01% 3885
2021
Q1 		$375K Buy
33,801
+17,136
+103% +$209K ﹤0.01% 3169
2020
Q4 		$208K Buy
16,665
+4,651
+39% +$60.3K ﹤0.01% 3099
2020
Q3 		$130K Sell
12,014
-1,863
-13% -$21.4K ﹤0.01% 2908
2020
Q2 		$155K Buy
+13,877
New +$106K ﹤0.01% 2707

Other funds holding CABA

T. Rowe Price Investment Management
T. Rowe Price Investment Management Baltimore, Maryland $145B AUM 22.78% 1-Year Est. Return
BCLSI
Bain Capital Life Sciences Investors Boston, Massachusetts $1.11B AUM 171.34% 1-Year Est. Return
Jennison Associates
Jennison Associates New York $167B AUM 44.17% 1-Year Est. Return
Adage Capital Partners
Adage Capital Partners Boston, Massachusetts $64.8B AUM 42.7% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return
CAM
Cormorant Asset Management Boston, Massachusetts $1.99B AUM 737.95% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
Marshall Wace
Marshall Wace London, United Kingdom $127B AUM 46.06% 1-Year Est. Return
Renaissance Technologies
Renaissance Technologies New York $72.6B AUM 54.88% 1-Year Est. Return

Two Sigma Investments's CABA Position: Q1 2026 in Review

Two Sigma Investments increased its Cabaletta Bio (CABA) stake by 36% in Q1 2026, buying an estimated $1.83M and bringing the position to 2,497,917 shares worth $6.72M. The position accounts for 0.01% of the portfolio, ranked #1736.

Two Sigma Investments first reported a position in CABA in Q2 2020 and has held it in 24 quarters since. 108 funds tracked by Wall St. Rank hold CABA as of Q1 2026.

  • Two Sigma Investments held 2,497,917 shares of Cabaletta Bio worth $6.72M as of Q1 2026.
  • Two Sigma Investments bought 658,118 Cabaletta Bio shares in Q1 2026, an estimated $1.83M.
  • Cabaletta Bio made up 0.01% of Two Sigma Investments's portfolio in Q1 2026, its #1736 holding.
  • Two Sigma Investments first reported a position in Cabaletta Bio in Q2 2020 and has held it in 24 quarters since.
  • 108 funds tracked by Wall St. Rank held Cabaletta Bio as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.