Biomea Fusion
BMEA
60 hedge funds and large institutions have $28.8M invested in Biomea Fusion in 2025 Q4 according to their latest regulatory filings, with 8 funds opening new positions, 17 increasing their positions, 17 reducing their positions, and 19 closing their positions.
269% more call options, than puts
Call options by funds: $2.21M | Put options by funds: $600K
0% more funds holding in top 10
Funds holding in top 10: 1 → 1 (0)
0% more repeat investments, than reductions
Existing positions increased: 17 | Existing positions reduced: 17
9.26% less ownership
Funds ownership: 42.12% → 32.86% (-9.3%)
18% less funds holding
Funds holding: 73 → 60 (-13)
43% less capital invested
Capital invested by funds: $50.6M → $28.8M (-$21.8M)
58% less first-time investments, than exits
New positions opened: 8 | Existing positions closed: 19
Top Buyers
| 1 |
Fidelity Investments
Boston,
Massachusetts
|
+$1.68M |
| 2 |
Marshall Wace
London,
United Kingdom
|
+$1.21M |
| 3 |
Vanguard Group
Malvern,
Pennsylvania
|
+$1.12M |
| 4 |
Mariner
Overland Park,
Kansas
|
+$486K |
| 5 |
UBS Group
Zurich,
Switzerland
|
+$399K |
Top Sellers
| 1 |
CAM
Cormorant Asset Management
Boston,
Massachusetts
|
-$7.21M |
| 2 |
HCM
Heights Capital Management
San Francisco,
California
|
-$2.9M |
| 3 |
BlackRock
New York
|
-$377K |
| 4 |
Federated Hermes
Pittsburgh,
Pennsylvania
|
-$365K |
| 5 |
Goldman Sachs
New York
|
-$276K |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
76
Nisa Investment Advisors
St. Louis,
Missouri
| – | -$588 | -291 | Closed |
|
|
EWA
77
EverSource Wealth Advisors
Birmingham,
Alabama
| – | -$357 | -177 | Closed |
|
|
IA
78
IFP Advisors
Tampa,
Florida
| – | -$109 | -54 | Closed |
|
BMEA Hedge Fund Activity: Q4 2025 in Review
60 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Biomea Fusion (BMEA) for Q4 2025, worth a combined $28.8M — down 43% from $50.6M a quarter earlier.
Sellers outnumbered buyers: 19 funds closed out of BMEA and 8 opened new positions — a net loss of 11 holders — while 17 trimmed existing stakes and 17 added.
The largest buyer was Fidelity Investments, adding an estimated $1.68M. The largest seller was Cormorant Asset Management, exiting entirely with an estimated $7.21M sold.
- 60 institutional investors held Biomea Fusion (BMEA) as of Q4 2025, down from 73 in Q3 2025.
- Funds reported $28.8M of Biomea Fusion stock for Q4 2025, down 43% quarter-over-quarter.
- 8 funds opened new Biomea Fusion positions in Q4 2025 and 19 closed out, a net change of -11 holders.
- The largest Biomea Fusion buyer in Q4 2025 was Fidelity Investments, an estimated $1.68M added.
- The largest Biomea Fusion seller in Q4 2025 was Cormorant Asset Management, an estimated $7.21M sold.
Based on aggregated 13F filings for Q4 2025.