|
1
|
Polaris Venture Management Co V
Boston,
Massachusetts
|
$26.6M
|
–
|
–
|
–
|
|
|
2
|
Opaleye Management
Boston,
Massachusetts
|
$6.49M
|
+$636K
|
+65,000
|
+15%
|
|
|
3
|
Franklin Resources
San Mateo,
California
|
$4.77M
|
–
|
–
|
–
|
|
|
4
|
Principal Financial Group
Des Moines,
Iowa
|
$4.01M
|
-$52.3K
|
-5,345
|
-2%
|
|
|
5
|
Putnam Investments
Boston,
Massachusetts
|
$3.22M
|
–
|
–
|
–
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$1.78M
|
-$64.2K
|
-6,557
|
-5%
|
|
|
7
|
BlackRock Advisors
Wilmington,
Delaware
|
$1.69M
|
-$28.7K
|
-2,935
|
-2%
|
|
|
8
|
BVF Inc
San Francisco,
California
|
$1.53M
|
–
|
–
|
–
|
|
|
9
|
Rhenman & Partners Asset Management
Stockholm,
Sweden
|
$1.43M
|
+$475K
|
+48,535
|
+81%
|
|
|
10
|
Millennium Management
New York
|
$764K
|
-$560K
|
-57,204
|
-50%
|
|
|
11
|
Northern Trust
Chicago,
Illinois
|
$699K
|
-$143K
|
-14,616
|
-22%
|
|
|
12
|
Credit Suisse
Zurich,
Switzerland
|
$620K
|
+$22.4K
|
+2,291
|
+5%
|
|
|
13
|
Raymond James & Associates
St Petersburg,
Florida
|
$505K
|
+$54.3K
|
+5,550
|
+17%
|
|
|
14
|
SSI Investment Management
Los Angeles,
California
|
$487K
|
+$39.5K
|
+4,040
|
+12%
|
|
|
15
|
Thompson Davis & Co
Richmond,
Virginia
|
$423K
|
+$252K
|
+25,750
|
+515%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$378K
|
-$33.6K
|
-3,430
|
-11%
|
|
|
17
|
California Public Employees Retirement System
Sacramento,
California
|
$348K
|
+$258K
|
+26,400
|
New
|
|
|
18
|
Bank of America
Charlotte,
North Carolina
|
$312K
|
+$231K
|
+23,562
|
+21,227%
|
|
|
19
|
Paloma Partners
Greenwich,
Connecticut
|
$299K
|
+$222K
|
+22,685
|
New
|
|
|
20
|
BlackRock Fund Advisors
San Francisco,
California
|
$213K
|
-$1.33M
|
-136,344
|
-89%
|
|
|
21
|
Banque Pictet & Cie
Geneva 73,
Switzerland
|
$213K
|
+$23.6K
|
+2,414
|
+18%
|
|
|
22
|
Prelude Capital Management
New York
|
$211K
|
+$29.4K
|
+3,000
|
+23%
|
|
|
23
|
BlackRock Institutional Trust
San Francisco,
California
|
$201K
|
-$640K
|
-65,431
|
-81%
|
|
|
24
|
Commonwealth of Pennsylvania Public School Employees Retirement System
Harrisburg,
Pennsylvania
|
$199K
|
+$148K
|
+15,133
|
New
|
|
|
25
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$197K
|
+$127K
|
+12,959
|
+644%
|
|
