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BCYC

Bicycle Therapeutics

109 hedge funds and large institutions have $278M invested in Bicycle Therapeutics in 2025 Q4 according to their latest regulatory filings, with 22 funds opening new positions, 35 increasing their positions, 29 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

146% more call options, than puts

Call options by funds: $2.33M | Put options by funds: $947K

100% more funds holding in top 10

Funds holding in top 10: 12 (+1)

100% more first-time investments, than exits

New positions opened: 22 | Existing positions closed: 11

21% more repeat investments, than reductions

Existing positions increased: 35 | Existing positions reduced: 29

10% more funds holding

Funds holding: 99109 (+10)

4.45% more ownership

Funds ownership: 74.01%78.46% (+4.4%)

3% less capital invested

Capital invested by funds: $286M → $278M (-$7.96M)

Holders
109
Holders Change
+10
Holders Change %
+10.1%
% of All Funds
1.33%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.02%
New
22
Increased
35
Reduced
29
Closed
11
Calls
$2.33M
Puts
$947K
Net Calls
+$1.39M
Net Calls Change
+$1.02M
Name Holding Trade Value Shares
Change
Change in
Stake
CGH
76
Crossmark Global Holdings
Texas
$80.7K +$66 +9 +0.1%
RhumbLine Advisers
77
RhumbLine Advisers
Massachusetts
$79.1K +$58.2K +7,896 +241%
Royal Bank of Canada
78
Royal Bank of Canada
Ontario, Canada
$76K -$15.1K -2,051 -16%
COPPSERS
79
Commonwealth of Pennsylvania Public School Employees Retirement System
Pennsylvania
$71.6K
Invesco
80
Invesco
Georgia
$71.5K +$74.4K +10,092 New
PWMAG
81
Pinnacle Wealth Management Advisory Group
New Jersey
$70.8K +$73.7K +10,000 New
Vontobel Holding
82
Vontobel Holding
Switzerland
$70.8K +$73.7K +10,000 New
BIG
83
Brooklyn Investment Group
New York
$69.3K +$75.3K +10,216 New
Legal & General Group
84
Legal & General Group
United Kingdom
$64.1K -$1.39M -188,863 -95%
CUAMC
85
China Universal Asset Management Company
China
$53.4K -$4.16K -564 -7%
FIA
86
FNY Investment Advisers
New York
$53K -$22.2K -3,014 -29%
CA
87
Clearstead Advisors
Ohio
$33K +$24.1K +3,262 +234%
N
88
Natixis
France
$31.6K +$19.9K +2,698 +139%
AssetMark Inc
89
AssetMark Inc
California
$25.7K +$22 +3 +0.1%
Mirae Asset Global Investments
90
Mirae Asset Global Investments
South Korea
$15.9K +$3.4K +461 +26%
TRCT
91
Tower Research Capital (TRC)
New York
$11.8K +$22 +3 +0.2%
GI
92
GAMMA Investing
California
$9.81K -$5.38K -730 -34%
Citigroup
93
Citigroup
New York
$9.14K -$9.66K -1,310 -50%
BNP Paribas Financial Markets
94
BNP Paribas Financial Markets
France
$7.9K +$2.25K +305 +38%
GFM
95
GF Fund Management
China
$6.44K -$634 -86 -9%
Barclays
96
Barclays
United Kingdom
$3.98K -$12.6K -1,710 -75%
HWM
97
HighMark Wealth Management
Minnesota
$3.08K
Fidelity Investments
98
Fidelity Investments
Massachusetts
$2.24K
Jones Financial Companies
99
Jones Financial Companies
Missouri
$1.77K
FFA
100
Farther Finance Advisors
California
$1.54K +$1.61K +218 New

BCYC Hedge Fund Activity: Q4 2025 in Review

109 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Bicycle Therapeutics (BCYC) for Q4 2025, worth a combined $278M — down 2.8% from $286M a quarter earlier.

Buyers outnumbered sellers: 22 funds opened new BCYC positions and 11 closed out — a net gain of 11 holders — while 35 added to existing stakes and 29 trimmed.

The largest buyer was Schroder Investment Management Group, opening a new position worth an estimated $4.31M. The largest seller was Millennium Management, cutting an estimated $5.37M.

  • 109 institutional investors held Bicycle Therapeutics (BCYC) as of Q4 2025, up from 99 in Q3 2025.
  • Funds reported $278M of Bicycle Therapeutics stock for Q4 2025, down 2.8% quarter-over-quarter.
  • 22 funds opened new Bicycle Therapeutics positions in Q4 2025 and 11 closed out, a net change of +11 holders.
  • The largest Bicycle Therapeutics buyer in Q4 2025 was Schroder Investment Management Group, an estimated $4.31M added.
  • The largest Bicycle Therapeutics seller in Q4 2025 was Millennium Management, an estimated $5.37M sold.

Based on aggregated 13F filings for Q4 2025.