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BCYC

Bicycle Therapeutics

109 hedge funds and large institutions have $278M invested in Bicycle Therapeutics in 2025 Q4 according to their latest regulatory filings, with 22 funds opening new positions, 35 increasing their positions, 29 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

146% more call options, than puts

Call options by funds: $2.33M | Put options by funds: $947K

100% more funds holding in top 10

Funds holding in top 10: 12 (+1)

100% more first-time investments, than exits

New positions opened: 22 | Existing positions closed: 11

21% more repeat investments, than reductions

Existing positions increased: 35 | Existing positions reduced: 29

10% more funds holding

Funds holding: 99109 (+10)

4.45% more ownership

Funds ownership: 74.01%78.46% (+4.4%)

3% less capital invested

Capital invested by funds: $286M → $278M (-$7.96M)

Holders
109
Holders Change
+10
Holders Change %
+10.1%
% of All Funds
1.33%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.02%
New
22
Increased
35
Reduced
29
Closed
11
Calls
$2.33M
Puts
$947K
Net Calls
+$1.39M
Net Calls Change
+$1.02M
Name Holding Trade Value Shares
Change
Change in
Stake
HCA
51
Harbor Capital Advisors
Illinois
$287K -$6.5K -882 -2%
Marshall Wace
52
Marshall Wace
United Kingdom
$275K +$286K +38,795 New
VIA
53
Virtus Investment Advisers
Connecticut
$253K +$167K +22,615 +173%
JF
54
Jump Financial
Illinois
$219K +$70.6K +9,579 +45%
WC
55
Woodstock Corp
Massachusetts
$206K +$38.5K +5,219 +22%
UBS Group
56
UBS Group
Switzerland
$182K +$105K +14,303 +126%
Geode Capital Management
57
Geode Capital Management
Massachusetts
$178K -$109K -14,796 -37%
Goldman Sachs
58
Goldman Sachs
New York
$175K +$182K +24,732 New
EGM
59
Engineers Gate Manager
New York
$170K +$78.3K +10,626 +79%
D.E. Shaw & Co
60
D.E. Shaw & Co
New York
$153K +$159K +21,548 New
State of New Jersey Common Pension Fund D
61
State of New Jersey Common Pension Fund D
New Jersey
$142K
Simplex Trading
62
Simplex Trading
Illinois
$142K +$147K +19,986 New
FRM
63
Fox Run Management
Connecticut
$140K +$146K +19,771 New
ACM
64
Aquatic Capital Management
Illinois
$133K +$139K +18,817 New
JP Morgan Chase
65
JP Morgan Chase
New York
$130K +$75.4K +10,228 +126%
PIC
66
Portland Investment Counsel
Ontario, Canada
$106K
FDCDDQ
67
Federation des caisses Desjardins du Quebec
Quebec, Canada
$101K
PNC Financial Services Group
68
PNC Financial Services Group
Pennsylvania
$100K +$7.8K +1,058 +8%
HKAM
69
Horizon Kinetics Asset Management
New York
$97.6K -$4.45K -604 -4%
EAM
70
Erste Asset Management
Austria
$94.9K
FA
71
Forefront Analytics
Pennsylvania
$94.7K +$98.6K +13,371 New
Cerity Partners
72
Cerity Partners
New York
$94.5K -$7.37K -1,000 -7%
VPIM
73
Vanguard Personalized Indexing Management
California
$90.5K -$1.3K -177 -1%
TAM
74
Tocqueville Asset Management
New York
$89.2K +$2.21K +300 +2%
Raymond James Financial
75
Raymond James Financial
Florida
$87.3K +$91K +12,336 New

BCYC Hedge Fund Activity: Q4 2025 in Review

109 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Bicycle Therapeutics (BCYC) for Q4 2025, worth a combined $278M — down 2.8% from $286M a quarter earlier.

Buyers outnumbered sellers: 22 funds opened new BCYC positions and 11 closed out — a net gain of 11 holders — while 35 added to existing stakes and 29 trimmed.

The largest buyer was Schroder Investment Management Group, opening a new position worth an estimated $4.31M. The largest seller was Millennium Management, cutting an estimated $5.37M.

  • 109 institutional investors held Bicycle Therapeutics (BCYC) as of Q4 2025, up from 99 in Q3 2025.
  • Funds reported $278M of Bicycle Therapeutics stock for Q4 2025, down 2.8% quarter-over-quarter.
  • 22 funds opened new Bicycle Therapeutics positions in Q4 2025 and 11 closed out, a net change of +11 holders.
  • The largest Bicycle Therapeutics buyer in Q4 2025 was Schroder Investment Management Group, an estimated $4.31M added.
  • The largest Bicycle Therapeutics seller in Q4 2025 was Millennium Management, an estimated $5.37M sold.

Based on aggregated 13F filings for Q4 2025.