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BCYC

Bicycle Therapeutics
BCYC

110 hedge funds and large institutions have $286M invested in Bicycle Therapeutics in 2025 Q2 according to their latest regulatory filings, with 29 funds opening new positions, 37 increasing their positions, 21 reducing their positions, and 14 closing their positions.

New
Increased
Maintained
Reduced
Closed

223% more call options, than puts

Call options by funds: $407K | Put options by funds: $126K

107% more first-time investments, than exits

New positions opened: 29 | Existing positions closed: 14

76% more repeat investments, than reductions

Existing positions increased: 37 | Existing positions reduced: 21

16% more funds holding

Funds holding: 95 → 110 (+15)

1.21% less ownership

Funds ownership: 87.48% → 86.26% (-1.2%)

19% less capital invested

Capital invested by funds: $354M → $286M (-$68M)

33% less funds holding in top 10

Funds holding in top 10: 3 → 2 (-1)

Holders
110
Holders Change
+15
Holders Change %
+15.79%
% of All Funds
1.45%
Holding in Top 10
2
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-33.33%
% of All Funds
0.03%
New
29
Increased
37
Reduced
21
Closed
14
Calls
$407K
Puts
$126K
Net Calls
+$281K
Net Calls Change
+$466K

Top Buyers

Rank Fund Capital Flow
1
Millennium Management
Millennium Management
New York
+$7.89M
2
Acadian Asset Management
Acadian Asset Management
Massachusetts
+$4.56M
3
DTC
Deep Track Capital
Connecticut
+$3.47M
4
TCM
Tybourne Capital Management
Hong Kong
+$3.32M
5
Bank of America
Bank of America
North Carolina
+$2.13M

Top Sellers

Rank Fund Capital Flow
1
Point72 Asset Management
Point72 Asset Management
Connecticut
-$15.3M
2
RCM
RA Capital Management
Massachusetts
-$9.28M
3
EC
EcoR1 Capital
California
-$7.73M
4
Axa
Axa
France
-$2.18M
5
BNP Paribas Asset Management
BNP Paribas Asset Management
France
-$1.42M
Name Holding Trade Value Shares
Change 		Change in
Stake
UBS Group
51
UBS Group
Switzerland
$232K -$313K -39,327 -54%
DekaBank Deutsche Girozentrale
52
DekaBank Deutsche Girozentrale
Germany
$211K – – –
Man Group
53
Man Group
United Kingdom
$199K +$228K +28,675 New
UBS AM
54
UBS AM
Illinois
$190K +$177K +22,200 +435%
Susquehanna International Group
55
Susquehanna International Group
Pennsylvania
$185K +$212K +26,567 New
AA
56
ALPS Advisors
Colorado
$179K +$205K +25,757 New
WC
57
Woodstock Corp
Massachusetts
$166K -$8.39K -1,054 -4%
TAM
58
Tocqueville Asset Management
New York
$159K +$36.6K +4,600 +25%
Jane Street
59
Jane Street
New York
$157K +$180K +22,607 New
QC
60
Quadrature Capital
United Kingdom
$123K +$141K +17,738 New
JF
61
Jump Financial
Illinois
$116K +$133K +16,740 New
PIC
62
Portland Investment Counsel
Ontario, Canada
$109K – – –
EGM
63
Engineers Gate Manager
New York
$107K +$123K +15,402 New
EAM
64
Erste Asset Management
Austria
$101K – – –
State of Tennessee, Department of Treasury
65
State of Tennessee, Department of Treasury
Tennessee
$100K +$115K +14,382 New
Cerity Partners
66
Cerity Partners
New York
$99.7K +$7.96K +1,000 +7%
HKAM
67
Horizon Kinetics Asset Management
New York
$95.9K -$4.81K -604 -4%
GCM
68
Graham Capital Management
Connecticut
$91.1K +$104K +13,102 New
PNC Financial Services Group
69
PNC Financial Services Group
Pennsylvania
$90.9K – – –
Ameriprise
70
Ameriprise
Minnesota
$85.5K +$98K +12,304 New
Squarepoint
71
Squarepoint
New York
$82.5K +$94.6K +11,874 New
CGH
72
Crossmark Global Holdings
Texas
$79.2K -$88 -11 -0.1%
VIA
73
Virtus Investment Advisers
Connecticut
$75.2K +$21.2K +2,659 +33%
SEI Investments
74
SEI Investments
Pennsylvania
$73.9K – – –
Royal Bank of Canada
75
Royal Bank of Canada
Ontario, Canada
$72K -$60.4K -7,578 -42%
1 2
3
4 5

BCYC Hedge Fund Activity: Q2 2025 in Review

110 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Bicycle Therapeutics (BCYC) for Q2 2025, worth a combined $286M — down 19% from $354M a quarter earlier.

Buyers outnumbered sellers: 29 funds opened new BCYC positions and 14 closed out — a net gain of 15 holders — while 37 added to existing stakes and 21 trimmed.

The largest buyer was Millennium Management, adding an estimated $7.89M. The largest seller was Point72 Asset Management, cutting an estimated $15.3M.

  • 110 institutional investors held Bicycle Therapeutics (BCYC) as of Q2 2025, up from 95 in Q1 2025.
  • Funds reported $286M of Bicycle Therapeutics stock for Q2 2025, down 19% quarter-over-quarter.
  • 29 funds opened new Bicycle Therapeutics positions in Q2 2025 and 14 closed out, a net change of +15 holders.
  • The largest Bicycle Therapeutics buyer in Q2 2025 was Millennium Management, an estimated $7.89M added.
  • The largest Bicycle Therapeutics seller in Q2 2025 was Point72 Asset Management, an estimated $15.3M sold.

Based on aggregated 13F filings for Q2 2025.