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BCYC

Bicycle Therapeutics
BCYC

95 hedge funds and large institutions have $354M invested in Bicycle Therapeutics in 2025 Q1 according to their latest regulatory filings, with 15 funds opening new positions, 28 increasing their positions, 30 reducing their positions, and 17 closing their positions.

New
Increased
Maintained
Reduced
Closed

0% more funds holding in top 10

Funds holding in top 10: 3 → 3 (0)

0.62% less ownership

Funds ownership: 88.1% → 87.48% (-0.62%)

7% less repeat investments, than reductions

Existing positions increased: 28 | Existing positions reduced: 30

2% less funds holding

Funds holding: 97 → 95 (-2)

12% less first-time investments, than exits

New positions opened: 15 | Existing positions closed: 17

40% less capital invested

Capital invested by funds: $586M → $354M (-$232M)

69% less call options, than puts

Call options by funds: $84K | Put options by funds: $269K

Holders
95
Holders Change
-2
Holders Change %
-2.06%
% of All Funds
1.27%
Holding in Top 10
3
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.04%
New
15
Increased
28
Reduced
30
Closed
17
Calls
$84K
Puts
$269K
Net Calls
-$185K
Net Calls Change
-$77K

Top Buyers

Rank Fund Capital Flow
1
LFCM
Long Focus Capital Management
Puerto Rico
+$8.85M
2
AC
Armistice Capital
New York
+$5.61M
3
JFG
Jefferies Financial Group
New York
+$4.82M
4
WP
Woodline Partners
California
+$4.29M
5
Millennium Management
Millennium Management
New York
+$3.26M

Top Sellers

Rank Fund Capital Flow
1
Point72 Asset Management
Point72 Asset Management
Connecticut
-$10.2M
2
TCM
Tybourne Capital Management
Hong Kong
-$8.17M
3
DTC
Deep Track Capital
Connecticut
-$6M
4
PHP
Parkman Healthcare Partners
Connecticut
-$4.93M
5
Verition Fund Management
Verition Fund Management
Connecticut
-$3.92M
Name Holding Trade Value Shares
Change 		Change in
Stake
PAI
26
Palo Alto Investors
California
$2.11M – – –
Handelsbanken Fonder
27
Handelsbanken Fonder
Sweden
$1.83M – – –
PA
28
Pinnacle Associates
New York
$1.82M -$147K -12,464 -5%
TD Asset Management
29
TD Asset Management
Ontario, Canada
$1.64M -$270K -22,924 -11%
ACM
30
Aquilo Capital Management
California
$1.46M -$592K -50,216 -23%
UOC
31
UBS O'Connor
Illinois
$1.26M +$807K +68,486 +85%
HCA
32
Harbor Capital Advisors
Illinois
$1.26M +$196K +16,624 +13%
Manulife (Manufacturers Life Insurance)
33
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$1.17M +$162K +13,752 +11%
Legal & General Group
34
Legal & General Group
United Kingdom
$1.17M -$40.3K -3,417 -2%
Citadel Advisors
35
Citadel Advisors
Florida
$1.1M -$167K -14,160 -10%
Acadian Asset Management
36
Acadian Asset Management
Massachusetts
$1.06M +$1.49M +126,062 New
State Street
37
State Street
Massachusetts
$727K -$24.9K -2,112 -2%
CM
38
Caption Management
Oklahoma
$692K -$961K -81,517 -50%
DCM
39
DAFNA Capital Management
California
$686K -$471K -40,000 -33%
UBS Group
40
UBS Group
Switzerland
$617K -$703K -59,659 -45%
NFGH
41
Nan Fung Group Holdings
Hong Kong
$585K – – –
SC
42
Shay Capital
New York
$509K +$707K +60,000 New
MCM
43
Moore Capital Management
New York
$425K +$589K +50,000 New
CSS
44
Cubist Systematic Strategies
Connecticut
$401K -$31.2K -2,650 -5%
Skandinaviska Enskilda Banken (SEB)
45
Skandinaviska Enskilda Banken (SEB)
Sweden
$363K – – –
DekaBank Deutsche Girozentrale
46
DekaBank Deutsche Girozentrale
Germany
$256K – – –
EC
47
EntryPoint Capital
New York
$245K -$177K -15,016 -34%
Goldman Sachs
48
Goldman Sachs
New York
$214K +$297K +25,192 New
WC
49
Woodstock Corp
Massachusetts
$212K – – –
Geode Capital Management
50
Geode Capital Management
Massachusetts
$181K -$205K -17,438 -45%
1
2
3 4 5

BCYC Hedge Fund Activity: Q1 2025 in Review

95 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Bicycle Therapeutics (BCYC) for Q1 2025, worth a combined $354M — down 40% from $586M a quarter earlier.

Sellers outnumbered buyers: 17 funds closed out of BCYC and 15 opened new positions — a net loss of 2 holders — while 30 trimmed existing stakes and 28 added.

The largest buyer was Long Focus Capital Management, adding an estimated $8.85M. The largest seller was Point72 Asset Management, cutting an estimated $10.2M.

  • 95 institutional investors held Bicycle Therapeutics (BCYC) as of Q1 2025, down from 97 in Q4 2024.
  • Funds reported $354M of Bicycle Therapeutics stock for Q1 2025, down 40% quarter-over-quarter.
  • 15 funds opened new Bicycle Therapeutics positions in Q1 2025 and 17 closed out, a net change of -2 holders.
  • The largest Bicycle Therapeutics buyer in Q1 2025 was Long Focus Capital Management, an estimated $8.85M added.
  • The largest Bicycle Therapeutics seller in Q1 2025 was Point72 Asset Management, an estimated $10.2M sold.

Based on aggregated 13F filings for Q1 2025.