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BioCryst Pharmaceuticals

273 hedge funds and large institutions have $1.66B invested in BioCryst Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 49 funds opening new positions, 92 increasing their positions, 101 reducing their positions, and 57 closing their positions.

New
Increased
Maintained
Reduced
Closed

200% more funds holding in top 10

Funds holding in top 10: 13 (+2)

55% more call options, than puts

Call options by funds: $12M | Put options by funds: $7.76M

12% more capital invested

Capital invested by funds: $1.48B → $1.66B (+$182M)

8.36% more ownership

Funds ownership: 92.5%100.86% (+8.4%)

9% less repeat investments, than reductions

Existing positions increased: 92 | Existing positions reduced: 101

5% less funds holding

Funds holding: 286273 (-13)

14% less first-time investments, than exits

New positions opened: 49 | Existing positions closed: 57

Holders
273
Holders Change
-13
Holders Change %
-4.55%
% of All Funds
3.32%
Holding in Top 10
3
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+200%
% of All Funds
0.04%
New
49
Increased
92
Reduced
101
Closed
57
Calls
$12M
Puts
$7.76M
Net Calls
+$4.27M
Net Calls Change
+$2.39M
Name Holding Trade Value Shares
Change
Change in
Stake
RHJA
26
Rice Hall James & Associates
California
$14.9M +$172K +23,757 +1%
Northern Trust
27
Northern Trust
Illinois
$14.5M -$254K -35,140 -2%
Stifel Financial
28
Stifel Financial
Missouri
$14.2M +$11K +1,525 +0.1%
Morgan Stanley
29
Morgan Stanley
New York
$13.6M -$25M -3,457,396 -66%
O
30
OrbiMed
New York
$13.6M +$6.07M +840,300 +93%
Squarepoint
31
Squarepoint
New York
$12.9M +$3.98M +550,532 +50%
Bank of America
32
Bank of America
North Carolina
$12M -$2.66M -367,262 -19%
NCM
33
Nantahala Capital Management
Connecticut
$10.6M +$9.81M +1,356,377 New
Invesco
34
Invesco
Georgia
$10.6M +$2.84M +392,521 +41%
Citadel Advisors
35
Citadel Advisors
Florida
$10.1M -$441K -60,980 -4%
D.E. Shaw & Co
36
D.E. Shaw & Co
New York
$9.73M -$3.34M -461,870 -27%
Dimensional Fund Advisors
37
Dimensional Fund Advisors
Texas
$9.59M +$8.88M +1,228,852 New
Point72 Asset Management
38
Point72 Asset Management
Connecticut
$9.47M +$7.05M +975,389 +410%
JAM
39
Jupiter Asset Management
United Kingdom
$9.34M -$6.2M -858,296 -42%
Jacobs Levy Equity Management
40
Jacobs Levy Equity Management
New Jersey
$8.05M +$4.78M +661,025 +178%
Hudson Bay Capital Management
41
Hudson Bay Capital Management
Connecticut
$7.94M +$7.35M +1,017,374 New
Aberdeen Group
42
Aberdeen Group
United Kingdom
$7.13M +$6.6M +913,593 New
JF
43
Jump Financial
Illinois
$7.11M -$100K -13,846 -1%
PHP
44
Parkman Healthcare Partners
Connecticut
$7.02M -$814K -112,607 -11%
JP Morgan Chase
45
JP Morgan Chase
New York
$6.58M -$2.09M -289,007 -26%
SFM
46
Sphera Funds Management
Israel
$6.54M +$6.06M +837,889 New
TCM
47
Tang Capital Management
California
$6.24M
SPS
48
Susquehanna Portfolio Strategies
Pennsylvania
$6.07M +$5.63M +778,521 New
Pictet Asset Management
49
Pictet Asset Management
Switzerland
$5.71M -$3.3M -455,809 -38%
Barclays
50
Barclays
United Kingdom
$5.67M -$404K -55,865 -7%