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BioCryst Pharmaceuticals

274 hedge funds and large institutions have $1.32B invested in BioCryst Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 41 funds opening new positions, 109 increasing their positions, 71 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed

99% more call options, than puts

Call options by funds: $9.58M | Put options by funds: $4.8M

71% more first-time investments, than exits

New positions opened: 41 | Existing positions closed: 24

54% more repeat investments, than reductions

Existing positions increased: 109 | Existing positions reduced: 71

6% more funds holding

Funds holding: 258274 (+16)

2.69% more ownership

Funds ownership: 80.95%83.64% (+2.7%)

4% more capital invested

Capital invested by funds: $1.26B → $1.32B (+$56.6M)

40% less funds holding in top 10

Funds holding in top 10: 53 (-2)

Holders
274
Holders Change
+16
Holders Change %
+6.2%
% of All Funds
3.67%
Holding in Top 10
3
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-40%
% of All Funds
0.04%
New
41
Increased
109
Reduced
71
Closed
24
Calls
$9.58M
Puts
$4.8M
Net Calls
+$4.78M
Net Calls Change
+$1.17M
Name Holding Trade Value Shares
Change
Change in
Stake
Stifel Financial
26
Stifel Financial
Missouri
$13.8M -$48.5K -6,007 -0.3%
Ameriprise
27
Ameriprise
Minnesota
$13.1M +$216K +26,725 +2%
D.E. Shaw & Co
28
D.E. Shaw & Co
New York
$11.9M +$10.3M +1,273,849 +404%
Bank of America
29
Bank of America
North Carolina
$10.8M +$4.32M +535,819 +60%
SBH
30
Segall Bryant & Hamill
Illinois
$9.98M -$741K -91,882 -6%
BFM
31
Boothbay Fund Management
New York
$9.93M -$487K -60,412 -4%
AQR Capital Management
32
AQR Capital Management
Connecticut
$9.01M +$2.92M +362,175 +43%
JP Morgan Chase
33
JP Morgan Chase
New York
$7.99M +$4.77M +591,207 +125%
Connor, Clark & Lunn Investment Management (CC&L)
34
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$7.82M +$3.3M +408,560 +64%
PHP
35
Parkman Healthcare Partners
Connecticut
$7.5M +$6.32M +783,681 +361%
Legal & General Group
36
Legal & General Group
United Kingdom
$7.36M +$5.7M +706,135 +257%
Invesco
37
Invesco
Georgia
$7.26M -$842K -104,445 -10%
AG
38
Algert Global
California
$7.2M +$1.89M +234,752 +32%
Qube Research & Technologies (QRT)
39
Qube Research & Technologies (QRT)
United Kingdom
$7.05M +$5.39M +667,821 +245%
TCM
40
Tang Capital Management
California
$6M
PP
41
PDT Partners
New York
$5.84M +$2.07M +256,439 +49%
Squarepoint
42
Squarepoint
New York
$5.74M +$3.27M +405,017 +113%
Acadian Asset Management
43
Acadian Asset Management
Massachusetts
$5.02M +$3.84M +475,564 +244%
Pictet Asset Management
44
Pictet Asset Management
Switzerland
$4.8M +$4.73M +585,882 +2,216%
SSA
45
Schonfeld Strategic Advisors
New York
$4.59M +$3.18M +394,479 +181%
Renaissance Technologies
46
Renaissance Technologies
New York
$4.54M +$486K +60,197 +11%
Bank of New York Mellon
47
Bank of New York Mellon
New York
$4.42M -$57K -7,061 -1%
Prudential Financial
48
Prudential Financial
New Jersey
$4.42M -$3.18M -393,723 -40%
Balyasny Asset Management
49
Balyasny Asset Management
Illinois
$4.4M +$456K +56,553 +11%
Fidelity Investments
50
Fidelity Investments
Massachusetts
$4.38M -$1.56M -193,654 -25%

BCRX Hedge Fund Activity: Q1 2025 in Review

274 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in BioCryst Pharmaceuticals (BCRX) for Q1 2025, worth a combined $1.32B — up 4.5% from $1.26B a quarter earlier.

Buyers outnumbered sellers: 41 funds opened new BCRX positions and 24 closed out — a net gain of 17 holders — while 109 added to existing stakes and 71 trimmed.

The largest buyer was Millennium Management, adding an estimated $24.4M. The largest seller was Avoro Capital Advisors, cutting an estimated $25.5M.

  • 274 institutional investors held BioCryst Pharmaceuticals (BCRX) as of Q1 2025, up from 258 in Q4 2024.
  • Funds reported $1.32B of BioCryst Pharmaceuticals stock for Q1 2025, up 4.5% quarter-over-quarter.
  • 41 funds opened new BioCryst Pharmaceuticals positions in Q1 2025 and 24 closed out, a net change of +17 holders.
  • The largest BioCryst Pharmaceuticals buyer in Q1 2025 was Millennium Management, an estimated $24.4M added.
  • The largest BioCryst Pharmaceuticals seller in Q1 2025 was Avoro Capital Advisors, an estimated $25.5M sold.

Based on aggregated 13F filings for Q1 2025.