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BioCryst Pharmaceuticals
BCRX

Overview Fund Activity

272 hedge funds and large institutions have $1.31B invested in BioCryst Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 41 funds opening new positions, 110 increasing their positions, 68 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
272
Holders Change
+14
Holders Change %
+5.43%
% of All Funds
3.69%
Holding in Top 10
3
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-40%
% of All Funds
0.04%
New
41
Increased
110
Reduced
68
Closed
24
Calls
$9.58M
Puts
$4.81M
Net Calls
+$4.78M
Net Calls Change
+$1.17M

Top Buyers

1
Millennium Management
Millennium Management
New York
+$22.7M
2
UBS Group
UBS Group
Switzerland
+$16.2M
3
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$9.55M
4
JAM
Jupiter Asset Management
United Kingdom
+$7.28M
5
PHP
Parkman Healthcare Partners
Connecticut
+$5.88M

Top Sellers

1
ACA
Avoro Capital Advisors
New York
-$23.7M
2
DM
Deerfield Management
New York
-$22.2M
3
RSCM
Rock Springs Capital Management
Maryland
-$18.4M
4
OIM
Oracle Investment Management
Connecticut
-$4.03M
5
WP
Woodline Partners
California
-$3.39M
Name Holding Trade Value Shares
Change 		Shares
Change %
Stifel Financial
26
Stifel Financial
Missouri
$13.8M -$45.1K -6,007 -0.3%
Ameriprise
27
Ameriprise
Minnesota
$13.1M +$200K +26,725 +2%
D.E. Shaw & Co
28
D.E. Shaw & Co
New York
$11.9M +$9.55M +1,273,849 +404%
Bank of America
29
Bank of America
North Carolina
$10.8M +$4.02M +535,819 +60%
SBH
30
Segall Bryant & Hamill
Illinois
$9.98M -$689K -91,882 -6%
BFM
31
Boothbay Fund Management
New York
$9.93M -$453K -60,412 -4%
AQR Capital Management
32
AQR Capital Management
Connecticut
$9.01M +$2.72M +362,175 +43%
JPMorgan Chase & Co
33
JPMorgan Chase & Co
New York
$7.99M +$4.43M +591,207 +125%
Connor, Clark & Lunn Investment Management (CC&L)
34
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$7.82M +$3.06M +408,560 +64%
PHP
35
Parkman Healthcare Partners
Connecticut
$7.5M +$5.88M +783,681 +361%
Legal & General Group
36
Legal & General Group
United Kingdom
$7.36M +$5.3M +706,135 +257%
Invesco
37
Invesco
Georgia
$7.26M -$783K -104,445 -10%
AG
38
Algert Global
California
$7.2M +$1.76M +234,752 +32%
Qube Research & Technologies (QRT)
39
Qube Research & Technologies (QRT)
United Kingdom
$7.05M +$5.01M +667,821 +245%
TCM
40
Tang Capital Management
California
$6M – – –
PP
41
PDT Partners
New York
$5.84M +$1.92M +256,439 +49%
Squarepoint
42
Squarepoint
New York
$5.74M +$3.04M +405,017 +113%
Acadian Asset Management
43
Acadian Asset Management
Massachusetts
$5.02M +$3.56M +475,564 +244%
Pictet Asset Management
44
Pictet Asset Management
Switzerland
$4.8M +$4.6M +585,882 +2,216%
SSA
45
Schonfeld Strategic Advisors
New York
$4.59M +$2.96M +394,479 +181%
Renaissance Technologies
46
Renaissance Technologies
New York
$4.54M +$451K +60,197 +11%
Bank of New York Mellon
47
Bank of New York Mellon
New York
$4.42M -$53K -7,061 -1%
Prudential Financial
48
Prudential Financial
New Jersey
$4.42M -$2.95M -393,723 -40%
Balyasny Asset Management
49
Balyasny Asset Management
Illinois
$4.4M +$424K +56,553 +11%
Fidelity Investments
50
Fidelity Investments
Massachusetts
$4.38M -$1.45M -193,654 -25%
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