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AstraZeneca

1,377 hedge funds and large institutions have $45.1B invested in AstraZeneca in 2025 Q4 according to their latest regulatory filings, with 246 funds opening new positions, 493 increasing their positions, 410 reducing their positions, and 120 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
1,377
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
21
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$591M
Puts
$420M
Net Calls
Net Calls Change

Top Buyers

1 +$420M
2 +$412M
3 +$327M
4
Citigroup
Citigroup
New York
+$204M
5
Barclays
Barclays
United Kingdom
+$180M

Top Sellers

1 -$924M
2 -$831M
3 -$550M
4
Primecap Management
Primecap Management
California
-$258M
5
Citadel Advisors
Citadel Advisors
Florida
-$241M
Name Holding Trade Value Shares
Change
Change in
Stake
ProShare Advisors
76
ProShare Advisors
Maryland
$85.7M
Capital World Investors
77
Capital World Investors
California
$84.1M
First Trust Advisors
78
First Trust Advisors
Illinois
$80.1M
State Street
79
State Street
Massachusetts
$77.4M
Aberdeen Group
80
Aberdeen Group
United Kingdom
$77.4M
Citadel Advisors
81
Citadel Advisors
Florida
$77.2M
EIP
82
Epoch Investment Partners
New York
$76M
PF
83
Phoenix Financial
Israel
$73.9M
Assenagon Asset Management
84
Assenagon Asset Management
Luxembourg
$72.4M
ZIC
85
ZWJ Investment Counsel
Georgia
$70.2M
HPG
86
Harvest Portfolios Group
Ontario, Canada
$69.4M
WFMPM
87
Woodley Farra Manion Portfolio Management
Indiana
$68.7M
Russell Investments Group
88
Russell Investments Group
United Kingdom
$67.9M
Mariner
89
Mariner
Kansas
$63.5M
Rockefeller Capital Management
90
Rockefeller Capital Management
New York
$60.2M
VanEck Associates
91
VanEck Associates
New York
$56.4M
1832 Asset Management
92
1832 Asset Management
Ontario, Canada
$53.2M
Cerity Partners
93
Cerity Partners
New York
$52.7M
OTPPB
94
Ontario Teachers' Pension Plan Board
Ontario, Canada
$52.6M
CAM
95
Cidel Asset Management
Ontario, Canada
$51.7M
FGI
96
Foresight Global Investors
New York
$51M
HJGA
97
Hardman Johnston Global Advisors
Connecticut
$50.3M
N
98
Nuveen
North Carolina
$49.9M
Deutsche Bank
99
Deutsche Bank
Germany
$48.8M
TIM
100
Thornburg Investment Management
New Mexico
$46.5M