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AstraZeneca
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Overview Fund Activity

1,197 hedge funds and large institutions have $34.1B invested in AstraZeneca in 2025 Q2 according to their latest regulatory filings, with 97 funds opening new positions, 454 increasing their positions, 430 reducing their positions, and 106 closing their positions.

Holders
1,197
Holders Change
-37
Holders Change %
-3%
% of All Funds
16.08%
Holding in Top 10
11
Holding in Top 10 Change
-10
Holding in Top 10 Change %
-47.62%
% of All Funds
0.15%
New
97
Increased
454
Reduced
430
Closed
106
Calls
$508M
Puts
$206M
Net Calls
+$302M
Net Calls Change
-$259M

Top Buyers

1
Fayez Sarofim & Co
1
Fayez Sarofim & Co
Texas
$262M
2
Acadian Asset Management
2
Acadian Asset Management
Massachusetts
$143M
3
Jennison Associates
3
Jennison Associates
New York
$850M
4
Raymond James Financial
4
Raymond James Financial
Florida
$264M
5
OTPPB
5
Ontario Teachers' Pension Plan Board
Ontario, Canada
$96.9M

Top Sellers

1
T. Rowe Price Associates
1
T. Rowe Price Associates
Maryland
$3.63B
2
Morgan Stanley
2
Morgan Stanley
New York
$854M
3
SFM
3
Soros Fund Management
New York
$0
4
Arrowstreet Capital
4
Arrowstreet Capital
Massachusetts
$80.8M
5
Fidelity Investments
5
Fidelity Investments
Massachusetts
$1.49B
Name Market Value Shares Shares
Change 		Shares
Change %
Envestnet Asset Management
26
Envestnet Asset Management
Illinois
$248M 3,553,554 -189,512 -5%
Royal Bank of Canada
27
Royal Bank of Canada
Ontario, Canada
$241M 3,453,236 +923,842 +37%
Wells Fargo
28
Wells Fargo
California
$226M 3,228,506 +99,429 +3%
WCM Investment Management
29
WCM Investment Management
California
$185M 2,653,082 -1,349,988 -34%
Janus Henderson Group
30
Janus Henderson Group
United Kingdom
$177M 2,531,810 +364,569 +17%
UBS Group
31
UBS Group
Switzerland
$166M 2,375,996 +666,403 +39%
MNA
32
Manning & Napier Advisors
New York
$150M 2,152,535 -902,693 -30%
AllianceBernstein
33
AllianceBernstein
Tennessee
$146M 2,084,626 -102,055 -5%
Acadian Asset Management
34
Acadian Asset Management
Massachusetts
$143M 2,043,850 +1,961,764 +2,390%
Marshall Wace
35
Marshall Wace
United Kingdom
$140M 1,999,931 +623,902 +45%
D.E. Shaw & Co
36
D.E. Shaw & Co
New York
$133M 1,904,943 +207,151 +12%
Natixis Advisors
37
Natixis Advisors
Massachusetts
$128M 1,837,925 -398,086 -18%
Citadel Advisors
38
Citadel Advisors
Florida
$128M 1,830,944 -215,277 -11%
Point72 Asset Management
39
Point72 Asset Management
Connecticut
$118M 1,685,551 +497,879 +42%
SC
40
Saturna Capital
Washington
$114M 1,633,715 -2,380 -0.1%
American Century Companies
41
American Century Companies
Missouri
$109M 1,560,326 -460,303 -23%
CIC
42
Crawford Investment Counsel
Georgia
$108M 1,538,860 -28,637 -2%
OTPPB
43
Ontario Teachers' Pension Plan Board
Ontario, Canada
$96.9M 1,387,174 +1,387,174 New
EIP
44
Epoch Investment Partners
New York
$92.5M 1,323,269 -673,431 -34%
Renaissance Technologies
45
Renaissance Technologies
New York
$91.1M 1,303,773 +1,004,573 +336%
Parnassus Investments
46
Parnassus Investments
California
$89.9M 1,286,979 +62,220 +5%
Principal Financial Group
47
Principal Financial Group
Iowa
$84.1M 1,204,045 +5,595 +0.5%
Assenagon Asset Management
48
Assenagon Asset Management
Luxembourg
$81.6M 1,167,516 +392,843 +51%
Arrowstreet Capital
49
Arrowstreet Capital
Massachusetts
$80.8M 1,155,576 -2,436,044 -68%
Stifel Financial
50
Stifel Financial
Missouri
$80.2M 1,147,853 -50,686 -4%
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