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AstraZeneca

1,249 hedge funds and large institutions have $37.6B invested in AstraZeneca in 2025 Q1 according to their latest regulatory filings, with 151 funds opening new positions, 521 increasing their positions, 375 reducing their positions, and 94 closing their positions.

New
Increased
Maintained
Reduced
Closed

191% more call options, than puts

Call options by funds: $855M | Put options by funds: $294M

69% more funds holding in top 10

Funds holding in top 10: 1322 (+9)

61% more first-time investments, than exits

New positions opened: 151 | Existing positions closed: 94

39% more repeat investments, than reductions

Existing positions increased: 521 | Existing positions reduced: 375

10% more capital invested

Capital invested by funds: $34.2B → $37.6B (+$3.47B)

3% more funds holding

Funds holding: 1,2181,249 (+31)

0.28% less ownership

Funds ownership: 16.58%16.3% (-0.28%)

Holders
1,249
Holders Change
+31
Holders Change %
+2.55%
% of All Funds
16.75%
Holding in Top 10
22
Holding in Top 10 Change
+9
Holding in Top 10 Change %
+69.23%
% of All Funds
0.29%
New
151
Increased
521
Reduced
375
Closed
94
Calls
$855M
Puts
$294M
Net Calls
+$561M
Net Calls Change
+$424M
Name Holding Trade Value Shares
Change
Change in
Stake
T. Rowe Price Associates
1
T. Rowe Price Associates
Maryland
$4.2B -$236M -1,632,546 -5%
Primecap Management
2
Primecap Management
California
$2.99B -$25.9M -179,021 -0.9%
Wellington Management Group
3
Wellington Management Group
Massachusetts
$2.62B -$102M -704,103 -4%
Bank of America
4
Bank of America
North Carolina
$2.34B +$565M +3,903,025 +32%
Capital International Investors
5
Capital International Investors
California
$2.3B -$450M -3,110,800 -17%
Fidelity Investments
6
Fidelity Investments
Massachusetts
$1.7B +$56.5M +390,477 +4%
Franklin Resources
7
Franklin Resources
California
$1.55B +$117M +810,712 +8%
Fisher Asset Management
8
Fisher Asset Management
Washington
$1.48B +$666M +4,602,804 +84%
Morgan Stanley
9
Morgan Stanley
New York
$1.16B -$111M -766,277 -9%
Sanders Capital
10
Sanders Capital
Florida
$1.11B -$8.51M -58,853 -0.8%
Goldman Sachs
11
Goldman Sachs
New York
$866M +$101M +696,625 +13%
Jennison Associates
12
Jennison Associates
New York
$776M -$352M -2,434,366 -32%
CIBC Private Wealth Group
13
CIBC Private Wealth Group
Georgia
$533M +$8.16M +56,434 +1%
Neuberger Berman Group
14
Neuberger Berman Group
New York
$442M +$23.2M +160,469 +6%
BlackRock
15
BlackRock
New York
$396M +$31.3M +216,507 +9%
Dimensional Fund Advisors
16
Dimensional Fund Advisors
Texas
$390M -$1.27M -8,747 -0.3%
TIM
17
Thornburg Investment Management
New Mexico
$380M +$837K +5,783 +2%
Boston Partners
18
Boston Partners
Massachusetts
$369M +$96.2M +664,583 +36%
Ameriprise
19
Ameriprise
Minnesota
$364M +$18.9M +130,532 +6%
Northern Trust
20
Northern Trust
Illinois
$343M -$1.87M -12,950 -0.6%
JP Morgan Chase
21
JP Morgan Chase
New York
$338M -$47.2M -326,403 -12%
Holocene Advisors
22
Holocene Advisors
New York
$327M +$10.6M +72,990 +3%
WCM Investment Management
23
WCM Investment Management
California
$295M +$19.7M +136,268 +7%
Invesco
24
Invesco
Georgia
$280M +$68.6M +474,329 +33%
Envestnet Asset Management
25
Envestnet Asset Management
Illinois
$275M +$14.1M +97,751 +6%

AZN Hedge Fund Activity: Q1 2025 in Review

1,249 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in AstraZeneca (AZN) for Q1 2025, worth a combined $37.6B — up 10% from $34.2B a quarter earlier.

Buyers outnumbered sellers: 151 funds opened new AZN positions and 94 closed out — a net gain of 57 holders — while 521 added to existing stakes and 375 trimmed.

The largest buyer was Fisher Asset Management, adding an estimated $666M. The largest seller was Capital International Investors, cutting an estimated $450M.

  • 1,249 institutional investors held AstraZeneca (AZN) as of Q1 2025, up from 1,218 in Q4 2024.
  • Funds reported $37.6B of AstraZeneca stock for Q1 2025, up 10% quarter-over-quarter.
  • 151 funds opened new AstraZeneca positions in Q1 2025 and 94 closed out, a net change of +57 holders.
  • The largest AstraZeneca buyer in Q1 2025 was Fisher Asset Management, an estimated $666M added.
  • The largest AstraZeneca seller in Q1 2025 was Capital International Investors, an estimated $450M sold.

Based on aggregated 13F filings for Q1 2025.