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Avalo Therapeutics

66 hedge funds and large institutions have $195M invested in Avalo Therapeutics in 2025 Q3 according to their latest regulatory filings, with 32 funds opening new positions, 15 increasing their positions, 8 reducing their positions, and 2 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,500% more first-time investments, than exits

New positions opened: 32 | Existing positions closed: 2

397% more capital invested

Capital invested by funds: $39.1M → $195M (+$156M)

110% more call options, than puts

Call options by funds: $1.39M | Put options by funds: $659K

88% more repeat investments, than reductions

Existing positions increased: 15 | Existing positions reduced: 8

83% more funds holding

Funds holding: 3666 (+30)

44.03% more ownership

Funds ownership: 72.44%116.46% (+44%)

Holders
66
Holders Change
+30
Holders Change %
+83.33%
% of All Funds
0.87%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
32
Increased
15
Reduced
8
Closed
2
Calls
$1.39M
Puts
$659K
Net Calls
+$726K
Net Calls Change
+$707K
Name Holding Trade Value Shares
Change
Change in
Stake
BCM
26
Boxer Capital Management
California
$1.59M +$1.08M +125,000 New
Geode Capital Management
27
Geode Capital Management
Massachusetts
$1.33M -$53.9K -6,271 -6%
EAM
28
Exome Asset Management
New York
$1.27M +$860K +100,036 New
PSC
29
Patient Square Capital
California
$1.27M +$860K +100,000 New
Renaissance Technologies
30
Renaissance Technologies
New York
$1.25M +$849K +98,700 New
RWP
31
RWA Wealth Partners
Massachusetts
$1.1M -$1.5M -174,500 -67%
CF
32
Cantor Fitzgerald
New York
$1.08M +$733K +85,247 New
DAM
33
DLD Asset Management
New York
$953K +$645K +75,000 New
Aberdeen Group
34
Aberdeen Group
United Kingdom
$925K +$626K +72,800 New
SCM
35
Sio Capital Management
New York
$917K
Marshall Wace
36
Marshall Wace
United Kingdom
$712K +$482K +56,009 New
QC
37
Quadrature Capital
United Kingdom
$696K +$379K +44,023 +401%
Two Sigma Investments
38
Two Sigma Investments
New York
$626K +$313K +36,353 +282%
Susquehanna International Group
39
Susquehanna International Group
Pennsylvania
$602K +$408K +47,398 New
State Street
40
State Street
Massachusetts
$578K +$391K +45,454 New
UBS Group
41
UBS Group
Switzerland
$575K -$331K -38,516 -46%
Walleye Capital
42
Walleye Capital
New York
$569K +$208K +24,130 +117%
LCM
43
Landscape Capital Management
New Jersey
$424K +$287K +33,337 New
ACM
44
ADAR1 Capital Management
Texas
$412K -$622K -72,337 -69%
BC
45
Birchview Capital
Vermont
$394K +$267K +31,000 New
HS
46
HighVista Strategies
Massachusetts
$353K +$239K +27,778 New
PCM
47
Prelude Capital Management
New York
$313K +$212K +24,628 New
Northern Trust
48
Northern Trust
Illinois
$236K -$35.2K -4,098 -18%
XT
49
XTX Topco
Cayman Islands
$177K +$120K +13,950 New
Dimensional Fund Advisors
50
Dimensional Fund Advisors
Texas
$143K +$96.5K +11,215 New

AVTX Hedge Fund Activity: Q3 2025 in Review

66 of the 7,625 institutional investors tracked by Wall St. Rank reported a position in Avalo Therapeutics (AVTX) for Q3 2025, worth a combined $195M — up 397% from $39.1M a quarter earlier.

Buyers outnumbered sellers: 32 funds opened new AVTX positions and 2 closed out — a net gain of 30 holders — while 15 added to existing stakes and 8 trimmed.

The largest buyer was Point72 Asset Management, opening a new position worth an estimated $9.06M. The largest seller was Deep Track Capital, cutting an estimated $3.63M.

  • 66 institutional investors held Avalo Therapeutics (AVTX) as of Q3 2025, up from 36 in Q2 2025.
  • Funds reported $195M of Avalo Therapeutics stock for Q3 2025, up 397% quarter-over-quarter.
  • 32 funds opened new Avalo Therapeutics positions in Q3 2025 and 2 closed out, a net change of +30 holders.
  • The largest Avalo Therapeutics buyer in Q3 2025 was Point72 Asset Management, an estimated $9.06M added.
  • The largest Avalo Therapeutics seller in Q3 2025 was Deep Track Capital, an estimated $3.63M sold.

Based on aggregated 13F filings for Q3 2025.