Two Sigma Investments
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Two Sigma Investments’s Avalo Therapeutics AVTX Stock Holding History

Two Sigma Investments’s Portfolio AVTX Stock Details AVTX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$962K Sell
64,425
-83,812
-57% -$1.31M ﹤0.01% 3288
2025
Q4 		$2.69M Buy
148,237
+98,995
+201% +$1.67M ﹤0.01% 2217
2025
Q3 		$626K Buy
49,242
+36,353
+282% +$313K ﹤0.01% 2879
2025
Q2 		$64.3K Buy
+12,889
New +$60.2K ﹤0.01% 3046
2022
Q2 		– Sell
-25
Closed -$51K – 2504
2022
Q1 		$51K Sell
25
-78
-76% -$196K ﹤0.01% 2486
2021
Q4 		$503K Sell
103
-151
-59% -$906K ﹤0.01% 3255
2021
Q3 		$1.6M Sell
254
-140
-36% -$1.13M ﹤0.01% 2190
2021
Q2 		$3.71M Buy
394
+158
+67% +$1.32M 0.01% 1387
2021
Q1 		$2.05M Buy
236
+71
+43% +$671K 0.01% 1690
2020
Q4 		$1.25M Sell
165
-40
-20% -$278K ﹤0.01% 1822
2020
Q3 		$1.34M Buy
205
+115
+128% +$864K ﹤0.01% 1564
2020
Q2 		$672K Buy
+90
New +$653K ﹤0.01% 1793

Other funds holding AVTX

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
T. Rowe Price Investment Management
T. Rowe Price Investment Management Baltimore, Maryland $145B AUM 22.78% 1-Year Est. Return
CP
Caligan Partners New York $1.5B AUM 518.95% 1-Year Est. Return
BI
BVF Inc San Francisco, California $3.14B AUM 249.53% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return
AAA
Affinity Asset Advisors New York $1.94B AUM 374.45% 1-Year Est. Return
NCM
Nantahala Capital Management New Canaan, Connecticut $2.72B AUM 121.58% 1-Year Est. Return
UBS Group
UBS Group Zurich, Switzerland $666B AUM 30.12% 1-Year Est. Return
Point72 Asset Management
Point72 Asset Management Stamford, Connecticut $78.1B AUM 55.25% 1-Year Est. Return
FCM
Farallon Capital Management San Francisco, California $17.5B AUM 50.95% 1-Year Est. Return