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Avalo Therapeutics

66 hedge funds and large institutions have $195M invested in Avalo Therapeutics in 2025 Q3 according to their latest regulatory filings, with 32 funds opening new positions, 15 increasing their positions, 8 reducing their positions, and 2 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,500% more first-time investments, than exits

New positions opened: 32 | Existing positions closed: 2

397% more capital invested

Capital invested by funds: $39.1M → $195M (+$156M)

110% more call options, than puts

Call options by funds: $1.39M | Put options by funds: $659K

88% more repeat investments, than reductions

Existing positions increased: 15 | Existing positions reduced: 8

83% more funds holding

Funds holding: 3666 (+30)

44.03% more ownership

Funds ownership: 72.44%116.46% (+44%)

Holders
66
Holders Change
+30
Holders Change %
+83.33%
% of All Funds
0.87%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
32
Increased
15
Reduced
8
Closed
2
Calls
$1.39M
Puts
$659K
Net Calls
+$726K
Net Calls Change
+$707K
Name Holding Trade Value Shares
Change
Change in
Stake
BI
1
BVF Inc
California
$17.2M +$2.81M +327,207 +32%
O
2
OrbiMed
New York
$17.1M +$3.29M +382,300 +40%
NCM
3
Nantahala Capital Management
Connecticut
$15.7M +$2.06M +240,000 +24%
Point72 Asset Management
4
Point72 Asset Management
Connecticut
$13.4M +$9.06M +1,053,983 New
AAA
5
Affinity Asset Advisors
New York
$12.8M +$3.43M +398,345 +66%
CP
6
Caligan Partners
New York
$10.6M +$7.17M +833,333 New
Balyasny Asset Management
7
Balyasny Asset Management
Illinois
$10.4M +$7.03M +817,436 New
SCM
8
Silverarc Capital Management
Massachusetts
$9.16M +$6.2M +720,922 New
Vanguard Group
9
Vanguard Group
Pennsylvania
$8.8M +$4.52M +525,696 +315%
RCM
10
RA Capital Management
Massachusetts
$8.43M -$2.32M -270,005 -29%
Bank of America
11
Bank of America
North Carolina
$7.7M +$1.71M +199,271 +49%
CC
12
Commodore Capital
New York
$6.14M
TCM
13
TCG Crossover Management
California
$6.14M
Citadel Advisors
14
Citadel Advisors
Florida
$6.12M +$4.14M +481,669 New
VCIM
15
Velan Capital Investment Management
Georgia
$3.35M +$935K +108,670 +70%
Adage Capital Partners
16
Adage Capital Partners
Massachusetts
$3.29M +$2.23M +258,769 New
BFM
17
Boothbay Fund Management
New York
$2.9M +$1.87M +216,976 +1,917%
Ameriprise
18
Ameriprise
Minnesota
$2.71M +$1.84M +213,572 New
SCM
19
Superstring Capital Management
New York
$2.39M +$1.62M +188,080 New
ABG
20
Ally Bridge Group
New York
$2.26M +$1.53M +178,100 New
IC
21
Ikarian Capital
Texas
$2.03M +$1.07M +124,477 +353%
BlackRock
22
BlackRock
New York
$1.96M -$14.2K -1,648 -1%
DTC
23
Deep Track Capital
Connecticut
$1.84M -$3.63M -422,503 -75%
PA
24
Perceptive Advisors
New York
$1.78M
Millennium Management
25
Millennium Management
New York
$1.75M +$1.18M +137,431 New

AVTX Hedge Fund Activity: Q3 2025 in Review

66 of the 7,625 institutional investors tracked by Wall St. Rank reported a position in Avalo Therapeutics (AVTX) for Q3 2025, worth a combined $195M — up 397% from $39.1M a quarter earlier.

Buyers outnumbered sellers: 32 funds opened new AVTX positions and 2 closed out — a net gain of 30 holders — while 15 added to existing stakes and 8 trimmed.

The largest buyer was Point72 Asset Management, opening a new position worth an estimated $9.06M. The largest seller was Deep Track Capital, cutting an estimated $3.63M.

  • 66 institutional investors held Avalo Therapeutics (AVTX) as of Q3 2025, up from 36 in Q2 2025.
  • Funds reported $195M of Avalo Therapeutics stock for Q3 2025, up 397% quarter-over-quarter.
  • 32 funds opened new Avalo Therapeutics positions in Q3 2025 and 2 closed out, a net change of +30 holders.
  • The largest Avalo Therapeutics buyer in Q3 2025 was Point72 Asset Management, an estimated $9.06M added.
  • The largest Avalo Therapeutics seller in Q3 2025 was Deep Track Capital, an estimated $3.63M sold.

Based on aggregated 13F filings for Q3 2025.