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Assembly Biosciences

75 hedge funds and large institutions have $376M invested in Assembly Biosciences in 2026 Q1 according to their latest regulatory filings, with 17 funds opening new positions, 28 increasing their positions, 17 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed

70% more first-time investments, than exits

New positions opened: 17 | Existing positions closed: 10

65% more repeat investments, than reductions

Existing positions increased: 28 | Existing positions reduced: 17

9% more funds holding

Funds holding: 6975 (+6)

1.23% less ownership

Funds ownership: 86.77%85.54% (-1.2%)

19% less capital invested

Capital invested by funds: $467M → $376M (-$90.3M)

67% less funds holding in top 10

Funds holding in top 10: 31 (-2)

Holders
75
Holders Change
+6
Holders Change %
+8.7%
% of All Funds
0.92%
Holding in Top 10
1
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-66.67%
% of All Funds
0.01%
New
17
Increased
28
Reduced
17
Closed
10
Calls
$6K
Puts
Net Calls
+$6K
Net Calls Change
-$72K
Name Holding Trade Value Shares
Change
Change in
Stake
GS
1
Gilead Sciences
California
$125M
FCM
2
Farallon Capital Management
California
$34.1M
RCM
3
RA Capital Management
Massachusetts
$28.3M
CC
4
Commodore Capital
New York
$27.8M
Janus Henderson Group
5
Janus Henderson Group
United Kingdom
$23.5M +$325K +11,384 +1%
PBA
6
Paradigm Biocapital Advisors
New York
$18.5M
VCM
7
Vanguard Capital Management
Pennsylvania
$13.6M +$14M +490,447 New
PHP
8
Parkman Healthcare Partners
Connecticut
$11.4M +$4.62M +161,870 +65%
Point72 Asset Management
9
Point72 Asset Management
Connecticut
$9.55M -$7.32M -256,504 -43%
Blackstone Inc
10
Blackstone Inc
New York
$8.24M -$625K -21,899 -7%
Millennium Management
11
Millennium Management
New York
$6.48M +$3.86M +135,429 +138%
BlackRock
12
BlackRock
New York
$5.63M +$298K +10,447 +5%
SC
13
Stempoint Capital
New York
$5.15M +$819K +28,707 +18%
BGI
14
B Group Inc
Texas
$4.88M
Marshall Wace
15
Marshall Wace
United Kingdom
$4.53M +$979K +34,325 +27%
Adage Capital Partners
16
Adage Capital Partners
Massachusetts
$4.47M
PSC
17
Patient Square Capital
California
$3.78M +$266K +9,315 +7%
Geode Capital Management
18
Geode Capital Management
Massachusetts
$3.69M +$47.5K +1,664 +1%
SSA
19
Schonfeld Strategic Advisors
New York
$3.34M +$1.89M +66,265 +122%
CM
20
Caption Management
Oklahoma
$2.27M -$706K -24,750 -23%
HS
21
HighVista Strategies
Massachusetts
$2.07M +$2.13M +74,735 New
VFT
22
Vanguard Fiduciary Trust
Pennsylvania
$1.99M +$2.04M +71,606 New
Qube Research & Technologies (QRT)
23
Qube Research & Technologies (QRT)
United Kingdom
$1.92M +$772K +27,071 +64%
State Street
24
State Street
Massachusetts
$1.57M +$106K +3,700 +7%
SFCM
25
Seven Fleet Capital Management
California
$1.56M -$502K -17,615 -24%

ASMB Hedge Fund Activity: Q1 2026 in Review

75 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Assembly Biosciences (ASMB) for Q1 2026, worth a combined $376M — down 19% from $467M a quarter earlier.

Buyers outnumbered sellers: 17 funds opened new ASMB positions and 10 closed out — a net gain of 7 holders — while 28 added to existing stakes and 17 trimmed.

The largest buyer was Parkman Healthcare Partners, adding an estimated $4.62M. The largest seller was Point72 Asset Management, cutting an estimated $7.32M.

  • 75 institutional investors held Assembly Biosciences (ASMB) as of Q1 2026, up from 69 in Q4 2025.
  • Funds reported $376M of Assembly Biosciences stock for Q1 2026, down 19% quarter-over-quarter.
  • 17 funds opened new Assembly Biosciences positions in Q1 2026 and 10 closed out, a net change of +7 holders.
  • The largest Assembly Biosciences buyer in Q1 2026 was Parkman Healthcare Partners, an estimated $4.62M added.
  • The largest Assembly Biosciences seller in Q1 2026 was Point72 Asset Management, an estimated $7.32M sold.

Based on aggregated 13F filings for Q1 2026.