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Assembly Biosciences

57 hedge funds and large institutions have $325M invested in Assembly Biosciences in 2025 Q3 according to their latest regulatory filings, with 31 funds opening new positions, 15 increasing their positions, 3 reducing their positions, and 7 closing their positions.

New
Increased
Maintained
Reduced
Closed

470% more capital invested

Capital invested by funds: $57M → $325M (+$268M)

400% more repeat investments, than reductions

Existing positions increased: 15 | Existing positions reduced: 3

343% more first-time investments, than exits

New positions opened: 31 | Existing positions closed: 7

121.47% more ownership

Funds ownership: 41.22%162.7% (+121%)

73% more funds holding

Funds holding: 3357 (+24)

0% more funds holding in top 10

Funds holding in top 10: 22 (0)

Holders
57
Holders Change
+24
Holders Change %
+72.73%
% of All Funds
0.75%
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.03%
New
31
Increased
15
Reduced
3
Closed
7
Calls
$11.4M
Puts
Net Calls
+$11.4M
Net Calls Change
+$11.4M
Name Holding Trade Value Shares
Change
Change in
Stake
GS
1
Gilead Sciences
California
$115M +$50.4M +2,295,920 +104%
FCM
2
Farallon Capital Management
California
$31.4M +$26.9M +1,227,590 New
RCM
3
RA Capital Management
Massachusetts
$26.1M +$22.4M +1,020,410 New
CC
4
Commodore Capital
New York
$25.6M +$21.9M +1,000,000 New
Janus Henderson Group
5
Janus Henderson Group
$19.2M +$16.5M +752,626 New
Vanguard Group
6
Vanguard Group
Pennsylvania
$12.9M +$5.45M +248,287 +98%
FLSM
7
Frazier Life Sciences Management
California
$11.7M +$10M +456,249 New
Blackstone Inc
8
Blackstone Inc
New York
$11.5M +$9.82M +447,789 New
Franklin Resources
9
Franklin Resources
California
$11.4M +$5.23M +238,169 New
Point72 Asset Management
10
Point72 Asset Management
Connecticut
$7.58M +$6.49M +296,017 New
PHP
11
Parkman Healthcare Partners
Connecticut
$6.43M +$5.51M +250,981 New
BGI
12
B Group Inc
Texas
$4.5M -$299K -13,644 -7%
BlackRock
13
BlackRock
New York
$4.36M +$1.77M +80,527 +90%
Renaissance Technologies
14
Renaissance Technologies
New York
$3.93M +$1.01M +46,090 +43%
PSC
15
Patient Square Capital
California
$3.46M +$2.97M +135,182 New
Susquehanna International Group
16
Susquehanna International Group
Pennsylvania
$3.35M +$2.87M +131,026 New
Geode Capital Management
17
Geode Capital Management
Massachusetts
$3.33M +$1.74M +79,080 +155%
SSA
18
Schonfeld Strategic Advisors
New York
$3.12M +$2.67M +121,888 New
Marshall Wace
19
Marshall Wace
United Kingdom
$2.18M +$1.87M +85,215 New
SC
20
Stempoint Capital
New York
$1.69M +$1.45M +66,130 New
Citadel Advisors
21
Citadel Advisors
Florida
$1.38M +$398K +18,153 +51%
State Street
22
State Street
Massachusetts
$1.15M +$676K +30,805 +220%
MCM
23
Monimus Capital Management
New Jersey
$1.08M
Northern Trust
24
Northern Trust
Illinois
$1.02M +$261K +11,880 +42%
MB
25
MPM BioImpact
Massachusetts
$1.02M +$870K +39,665 New

ASMB Hedge Fund Activity: Q3 2025 in Review

57 of the 7,630 institutional investors tracked by Wall St. Rank reported a position in Assembly Biosciences (ASMB) for Q3 2025, worth a combined $325M — up 470% from $57M a quarter earlier.

Buyers outnumbered sellers: 31 funds opened new ASMB positions and 7 closed out — a net gain of 24 holders — while 15 added to existing stakes and 3 trimmed.

The largest buyer was Gilead Sciences, adding an estimated $50.4M. The largest seller was B Group Inc, cutting an estimated $299K.

  • 57 institutional investors held Assembly Biosciences (ASMB) as of Q3 2025, up from 33 in Q2 2025.
  • Funds reported $325M of Assembly Biosciences stock for Q3 2025, up 470% quarter-over-quarter.
  • 31 funds opened new Assembly Biosciences positions in Q3 2025 and 7 closed out, a net change of +24 holders.
  • The largest Assembly Biosciences buyer in Q3 2025 was Gilead Sciences, an estimated $50.4M added.
  • The largest Assembly Biosciences seller in Q3 2025 was B Group Inc, an estimated $299K sold.

Based on aggregated 13F filings for Q3 2025.