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Assembly Biosciences

57 hedge funds and large institutions have $325M invested in Assembly Biosciences in 2025 Q3 according to their latest regulatory filings, with 31 funds opening new positions, 15 increasing their positions, 3 reducing their positions, and 7 closing their positions.

New
Increased
Maintained
Reduced
Closed

470% more capital invested

Capital invested by funds: $57M → $325M (+$268M)

400% more repeat investments, than reductions

Existing positions increased: 15 | Existing positions reduced: 3

343% more first-time investments, than exits

New positions opened: 31 | Existing positions closed: 7

121.47% more ownership

Funds ownership: 41.22%162.7% (+121%)

73% more funds holding

Funds holding: 3357 (+24)

0% more funds holding in top 10

Funds holding in top 10: 22 (0)

Holders
57
Holders Change
+24
Holders Change %
+72.73%
% of All Funds
0.75%
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.03%
New
31
Increased
15
Reduced
3
Closed
7
Calls
$11.4M
Puts
Net Calls
+$11.4M
Net Calls Change
+$11.4M
Name Holding Trade Value Shares
Change
Change in
Stake
PWM
26
Palumbo Wealth Management
New York
$891K +$354K +16,131 +86%
Jane Street
27
Jane Street
New York
$866K +$742K +33,828 New
EA
28
Ellsworth Advisors
Ohio
$852K +$657K +29,950 New
EI
29
EAM Investors
California
$744K +$638K +29,072 New
Federated Hermes
30
Federated Hermes
Pennsylvania
$650K
Walleye Capital
31
Walleye Capital
New York
$627K +$538K +24,501 New
Acadian Asset Management
32
Acadian Asset Management
Massachusetts
$595K +$62.9K +2,869 +14%
Millennium Management
33
Millennium Management
New York
$553K +$474K +21,608 New
ACM
34
ADAR1 Capital Management
Texas
$485K +$416K +18,947 New
QC
35
Quadrature Capital
United Kingdom
$459K +$394K +17,935 New
Goldman Sachs
36
Goldman Sachs
New York
$452K +$387K +17,656 New
CSS
37
Cubist Systematic Strategies
Connecticut
$414K +$355K +16,161 New
UBS Group
38
UBS Group
Switzerland
$404K +$282K +12,830 +437%
BCM
39
Bridgeway Capital Management
Texas
$390K
XT
40
XTX Topco
Cayman Islands
$328K +$281K +12,806 New
TI
41
Trexquant Investment
Connecticut
$321K +$275K +12,526 New
GCP
42
GSA Capital Partners
United Kingdom
$318K -$53.1K -2,420 -16%
Connor, Clark & Lunn Investment Management (CC&L)
43
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$286K +$245K +11,156 New
Qube Research & Technologies (QRT)
44
Qube Research & Technologies (QRT)
United Kingdom
$282K +$242K +11,030 New
Barclays
45
Barclays
United Kingdom
$101K +$25.9K +1,182 +43%
Morgan Stanley
46
Morgan Stanley
New York
$90.3K +$30.2K +1,378 +64%
Bank of America
47
Bank of America
North Carolina
$86.3K +$72.8K +3,319 +6,383%
Northwestern Mutual Wealth Management
48
Northwestern Mutual Wealth Management
Wisconsin
$6.66K
RhumbLine Advisers
49
RhumbLine Advisers
Massachusetts
$4.86K
Wells Fargo
50
Wells Fargo
California
$3.71K

ASMB Hedge Fund Activity: Q3 2025 in Review

57 of the 7,630 institutional investors tracked by Wall St. Rank reported a position in Assembly Biosciences (ASMB) for Q3 2025, worth a combined $325M — up 470% from $57M a quarter earlier.

Buyers outnumbered sellers: 31 funds opened new ASMB positions and 7 closed out — a net gain of 24 holders — while 15 added to existing stakes and 3 trimmed.

The largest buyer was Gilead Sciences, adding an estimated $50.4M. The largest seller was B Group Inc, cutting an estimated $299K.

  • 57 institutional investors held Assembly Biosciences (ASMB) as of Q3 2025, up from 33 in Q2 2025.
  • Funds reported $325M of Assembly Biosciences stock for Q3 2025, up 470% quarter-over-quarter.
  • 31 funds opened new Assembly Biosciences positions in Q3 2025 and 7 closed out, a net change of +24 holders.
  • The largest Assembly Biosciences buyer in Q3 2025 was Gilead Sciences, an estimated $50.4M added.
  • The largest Assembly Biosciences seller in Q3 2025 was B Group Inc, an estimated $299K sold.

Based on aggregated 13F filings for Q3 2025.