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Assembly Biosciences

75 hedge funds and large institutions have $376M invested in Assembly Biosciences in 2026 Q1 according to their latest regulatory filings, with 17 funds opening new positions, 28 increasing their positions, 17 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed

70% more first-time investments, than exits

New positions opened: 17 | Existing positions closed: 10

65% more repeat investments, than reductions

Existing positions increased: 28 | Existing positions reduced: 17

9% more funds holding

Funds holding: 6975 (+6)

1.23% less ownership

Funds ownership: 86.77%85.54% (-1.2%)

19% less capital invested

Capital invested by funds: $467M → $376M (-$90.3M)

67% less funds holding in top 10

Funds holding in top 10: 31 (-2)

Holders
75
Holders Change
+6
Holders Change %
+8.7%
% of All Funds
0.92%
Holding in Top 10
1
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-66.67%
% of All Funds
0.01%
New
17
Increased
28
Reduced
17
Closed
10
Calls
$6K
Puts
Net Calls
+$6K
Net Calls Change
-$72K
Name Holding Trade Value Shares
Change
Change in
Stake
JP Morgan Chase
26
JP Morgan Chase
New York
$1.44M +$166K +5,803 +12%
MCM
27
Monimus Capital Management
New Jersey
$1.34M +$288K +10,089 +26%
GCP
28
GSA Capital Partners
United Kingdom
$1.25M +$923K +32,350 +255%
Northern Trust
29
Northern Trust
Illinois
$1.14M -$6.08K -213 -0.5%
EP
30
Eversept Partners
New York
$1.13M -$3.39M -118,787 -74%
Arrowstreet Capital
31
Arrowstreet Capital
Massachusetts
$1.09M +$46.6K +1,634 +4%
Goldman Sachs
32
Goldman Sachs
New York
$1M +$40.2K +1,411 +4%
Jane Street
33
Jane Street
New York
$957K -$548K -19,203 -36%
Morgan Stanley
34
Morgan Stanley
New York
$917K +$300K +10,521 +47%
Susquehanna International Group
35
Susquehanna International Group
Pennsylvania
$914K -$1.35M -47,445 -59%
6CM
36
683 Capital Management
New York
$773K
Barclays
37
Barclays
United Kingdom
$751K +$65.9K +2,309 +9%
Wellington Management Group
38
Wellington Management Group
Massachusetts
$735K +$756K +26,496 New
Citadel Advisors
39
Citadel Advisors
Florida
$706K -$212K -7,429 -23%
Squarepoint
40
Squarepoint
New York
$661K +$679K +23,804 New
TI
41
Trexquant Investment
Connecticut
$631K -$158K -5,535 -20%
Connor, Clark & Lunn Investment Management (CC&L)
42
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$604K +$27.4K +959 +5%
Two Sigma Investments
43
Two Sigma Investments
New York
$570K +$586K +20,550 New
ACM
44
ADAR1 Capital Management
Texas
$554K +$5.71K +200 +1%
PWM
45
Palumbo Wealth Management
New York
$545K -$504K -17,662 -47%
Federated Hermes
46
Federated Hermes
Pennsylvania
$525K -$185K -6,490 -26%
VPM
47
Vanguard Portfolio Management
Pennsylvania
$492K +$506K +17,723 New
Hudson Bay Capital Management
48
Hudson Bay Capital Management
Connecticut
$466K +$49.9K +1,749 +12%
Renaissance Technologies
49
Renaissance Technologies
New York
$434K +$183K +6,411 +69%
SPS
50
Susquehanna Portfolio Strategies
Pennsylvania
$391K +$5.62K +197 +1%

ASMB Hedge Fund Activity: Q1 2026 in Review

75 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Assembly Biosciences (ASMB) for Q1 2026, worth a combined $376M — down 19% from $467M a quarter earlier.

Buyers outnumbered sellers: 17 funds opened new ASMB positions and 10 closed out — a net gain of 7 holders — while 28 added to existing stakes and 17 trimmed.

The largest buyer was Parkman Healthcare Partners, adding an estimated $4.62M. The largest seller was Point72 Asset Management, cutting an estimated $7.32M.

  • 75 institutional investors held Assembly Biosciences (ASMB) as of Q1 2026, up from 69 in Q4 2025.
  • Funds reported $376M of Assembly Biosciences stock for Q1 2026, down 19% quarter-over-quarter.
  • 17 funds opened new Assembly Biosciences positions in Q1 2026 and 10 closed out, a net change of +7 holders.
  • The largest Assembly Biosciences buyer in Q1 2026 was Parkman Healthcare Partners, an estimated $4.62M added.
  • The largest Assembly Biosciences seller in Q1 2026 was Point72 Asset Management, an estimated $7.32M sold.

Based on aggregated 13F filings for Q1 2026.