Two Sigma Investments
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Two Sigma Investments’s Assembly Biosciences ASMB Stock Holding History

Two Sigma Investments’s Portfolio ASMB Stock Details ASMB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$570K Buy
+20,550
New +$586K ﹤0.01% 3654
2024
Q1 		– Sell
-11,254
Closed -$111K – 3025
2023
Q4 		$111K Buy
+11,254
New +$107K ﹤0.01% 2930
2023
Q2 		– Sell
-3,192
Closed -$32.2K – 2996
2023
Q1 		$32.2K Buy
+3,192
New +$53.8K ﹤0.01% 2806
2022
Q4 		– Sell
-2,672
Closed -$53K – 2793
2022
Q3 		$53K Sell
2,672
-2,531
-49% -$61.2K ﹤0.01% 2310
2022
Q2 		$131K Buy
+5,203
New +$120K ﹤0.01% 2233
2022
Q1 		– Sell
-15,858
Closed -$443K – 2693
2021
Q4 		$443K Buy
+15,858
New +$520K ﹤0.01% 3367
2021
Q3 		– Sell
-53,860
Closed -$2.51M – 4221
2021
Q2 		$2.51M Buy
53,860
+7,710
+17% +$382K 0.01% 1692
2021
Q1 		$2.55M Buy
+46,150
New +$3.06M 0.01% 1519
2020
Q4 		– Sell
-1,147
Closed -$226K – 3317
2020
Q3 		$226K Sell
1,147
-5,283
-82% -$1.33M ﹤0.01% 2749
2020
Q2 		$1.8M Buy
6,430
+1,986
+45% +$463K 0.01% 1153
2020
Q1 		$791K Sell
4,444
-4,404
-50% -$944K 0.01% 1600
2019
Q4 		$2.17M Buy
8,848
+2,208
+33% +$407K 0.01% 1520
2019
Q3 		$783K Sell
6,640
-5,920
-47% -$896K ﹤0.01% 2187
2019
Q2 		$2.03M Buy
12,560
+4,059
+48% +$772K 0.01% 1435
2019
Q1 		$2.01M Buy
8,501
+7,263
+587% +$1.84M 0.01% 1415
2018
Q4 		$336K Buy
+1,238
New +$358K ﹤0.01% 2375
2018
Q2 		– Sell
-534
Closed -$315K – 3285
2018
Q1 		$315K Buy
+534
New +$331K ﹤0.01% 2750
2017
Q4 		– Sell
-1,427
Closed -$598K – 3072
2017
Q3 		$598K Buy
1,427
+382
+37% +$117K ﹤0.01% 2039
2017
Q2 		$259K Buy
+1,045
New +$294K ﹤0.01% 2697

Other funds holding ASMB

GS
Gilead Sciences Foster City, California $2.12B AUM 143.53% 1-Year Est. Return
FCM
Farallon Capital Management San Francisco, California $17.5B AUM 50.95% 1-Year Est. Return
RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return
CC
Commodore Capital New York $1.73B AUM 298.96% 1-Year Est. Return
Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
PBA
Paradigm Biocapital Advisors New York $4.89B AUM 251.12% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
PHP
Parkman Healthcare Partners Stamford, Connecticut $970M AUM 79.46% 1-Year Est. Return
Point72 Asset Management
Point72 Asset Management Stamford, Connecticut $78.1B AUM 55.25% 1-Year Est. Return
Blackstone Inc
Blackstone Inc New York $25.6B AUM 26.83% 1-Year Est. Return

Two Sigma Investments's ASMB Position: Q1 2026 in Review

Two Sigma Investments opened a new position in Assembly Biosciences (ASMB) in Q1 2026: 20,550 shares worth $570K. The stake represents ﹤0.01% of the portfolio and ranks #3654 among its holdings. This is a return to the name: Two Sigma Investments previously reported a position in ASMB as recently as Q4 2023.

Two Sigma Investments first reported a position in ASMB in Q2 2017 and has held it in 19 quarters since. The position peaked at $2.55M in Q1 2021. 75 funds tracked by Wall St. Rank hold ASMB as of Q1 2026.

  • Two Sigma Investments held 20,550 shares of Assembly Biosciences worth $570K as of Q1 2026.
  • Assembly Biosciences was a new Two Sigma Investments position in Q1 2026.
  • Assembly Biosciences made up ﹤0.01% of Two Sigma Investments's portfolio in Q1 2026, its #3654 holding.
  • Two Sigma Investments first reported a position in Assembly Biosciences in Q2 2017 and has held it in 19 quarters since.
  • Two Sigma Investments's Assembly Biosciences position peaked at $2.55M in Q1 2021.
  • 75 funds tracked by Wall St. Rank held Assembly Biosciences as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.