|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$81.5M
|
–
|
–
|
–
|
|
|
2
|
New Leaf Venture Partners
New York
|
$51.6M
|
+$44.8M
|
+382,745
|
New
|
|
|
3
|
Baker Bros. Advisors
New York
|
$51.2M
|
+$20.2M
|
+172,609
|
+83%
|
|
|
4
|
|
$44.8M
|
–
|
–
|
–
|
|
|
5
|
Perceptive Advisors
New York
|
$19.7M
|
+$8.65M
|
+73,985
|
+91%
|
|
|
6
|
HealthCor Management
New York
|
$19.6M
|
+$2.44M
|
+20,833
|
+17%
|
|
|
7
|
PFM Health Sciences
San Francisco,
California
|
$19.5M
|
+$6.3M
|
+53,871
|
+59%
|
|
|
8
|
Kingdon Capital Management
New York
|
$14.5M
|
+$1.76M
|
+15,063
|
+16%
|
|
|
9
|
|
$11.6M
|
-$673K
|
-5,753
|
-6%
|
|
|
10
|
BlackRock Fund Advisors
San Francisco,
California
|
$10.7M
|
+$6.06M
|
+51,822
|
+190%
|
|
|
11
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$9.58M
|
-$123K
|
-1,050
|
-1%
|
|
|
12
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$8.12M
|
–
|
–
|
–
|
|
|
13
|
Opaleye Management
Boston,
Massachusetts
|
$5.28M
|
+$4.58M
|
+39,167
|
New
|
|
|
14
|
RA Capital Management
Boston,
Massachusetts
|
$5.19M
|
-$13M
|
-111,287
|
-74%
|
|
|
15
|
Cormorant Asset Management
Boston,
Massachusetts
|
$4.49M
|
–
|
–
|
–
|
|
|
16
|
|
$4.41M
|
-$19.6K
|
-168
|
-0.5%
|
|
|
17
|
Vanguard Group
Malvern,
Pennsylvania
|
$4.11M
|
+$639K
|
+5,464
|
+22%
|
|
|
18
|
Wellington Management Group
Boston,
Massachusetts
|
$4.01M
|
+$2.34M
|
+20,041
|
+205%
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$1.65M
|
+$32K
|
+274
|
+2%
|
|
|
20
|
State Street
Boston,
Massachusetts
|
$1.54M
|
+$68.1K
|
+582
|
+5%
|
|
|
21
|
BlackRock Institutional Trust
San Francisco,
California
|
$1.42M
|
+$116K
|
+991
|
+10%
|
|
|
22
|
Geode Capital Management
Boston,
Massachusetts
|
$1.34M
|
+$30.1K
|
+257
|
+3%
|
|
|
23
|
Principal Financial Group
Des Moines,
Iowa
|
$1.01M
|
-$16.5K
|
-141
|
-2%
|
|
|
24
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$940K
|
+$816K
|
+6,974
|
+63,400%
|
|
|
25
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$879K
|
+$538K
|
+4,603
|
+239%
|
|
