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Apellis Pharmaceuticals
APLS

Overview Fund Activity

243 hedge funds and large institutions have $2.26B invested in Apellis Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 43 funds opening new positions, 106 increasing their positions, 68 reducing their positions, and 49 closing their positions.

Holders
243
Holders Change
-11
Holders Change %
-4.33%
% of All Funds
3.26%
Holding in Top 10
4
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-33.33%
% of All Funds
0.05%
New
43
Increased
106
Reduced
68
Closed
49
Calls
$47.3M
Puts
$9.73M
Net Calls
+$37.5M
Net Calls Change
+$30.8M

Top Buyers

1
Marshall Wace
1
Marshall Wace
United Kingdom
$46.8M
2
DTC
2
Deep Track Capital
Connecticut
$121M
3
AQR Capital Management
3
AQR Capital Management
Connecticut
$103M
4
UBS Group
4
UBS Group
Switzerland
$82M
5
Amundi
5
Amundi
France
$28.6M

Top Sellers

1
Wellington Management Group
1
Wellington Management Group
Massachusetts
$155M
2
Fidelity Investments
2
Fidelity Investments
Massachusetts
$334K
3
Man Group
3
Man Group
United Kingdom
$0
4
OCA
4
Octagon Capital Advisors
New York
$15.6M
5
National Bank of Canada
5
National Bank of Canada
Quebec, Canada
$0
Name Market Value Shares Shares
Change 		Shares
Change %
Manulife (Manufacturers Life Insurance)
151
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$380K 21,973 -2,964 -12%
Creative Planning
152
Creative Planning
Kansas
$378K 21,838 +21,838 New
A
153
AlphaQuest
New York
$368K 21,240 -34,864 -62%
TSS
154
Two Sigma Securities
New York
$366K 21,168 +21,168 New
MFG
155
Merit Financial Group
Georgia
$365K 21,096 -12,666 -38%
CC
156
Corton Capital
Ontario, Canada
$364K 21,011 +21,011 New
Mercer Global Advisors
157
Mercer Global Advisors
Colorado
$362K 20,941 -821 -4%
Teacher Retirement System of Texas
158
Teacher Retirement System of Texas
Texas
$351K 20,287 +1,828 +10%
Fidelity Investments
159
Fidelity Investments
Massachusetts
$334K 19,292 -1,483,917 -99%
Zurich Cantonal Bank
160
Zurich Cantonal Bank
Switzerland
$331K 19,128 -763 -4%
X
161
Xponance
Pennsylvania
$318K 18,358 +2,261 +14%
HT
162
HAP Trading
New York
$310K 17,937 +17,937 New
DWAM
163
Duncan Williams Asset Management
Tennessee
$294K 17,005 -4,120 -20%
ACM
164
ADAR1 Capital Management
Texas
$294K 17,000 – –
QC
165
Quadrature Capital
United Kingdom
$291K 16,798 +16,798 New
Group One Trading
166
Group One Trading
Illinois
$290K 16,778 -13,263 -44%
BJL
167
Brighton Jones LLC
Washington
$286K 16,539 +16,539 New
Wolverine Trading
168
Wolverine Trading
Illinois
$282K 16,198 +2,770 +21%
EFM
169
E Fund Management
China
$278K 16,057 -778 -5%
SPA
170
Sherbrooke Park Advisers
New York
$276K 15,939 +15,939 New
KK
171
KLP Kapitalforvaltning
Norway
$270K 15,600 +2,600 +20%
Victory Capital Management
172
Victory Capital Management
Texas
$270K 15,575 -199,577 -93%
BC
173
Birchview Capital
Vermont
$242K 14,000 – –
FRM
174
Fox Run Management
Connecticut
$242K 13,967 -1,745 -11%
EF
175
Empowered Funds
Pennsylvania
$233K 13,487 +13,487 New
5 6
7
8 9