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Apellis Pharmaceuticals
APLS

Overview Fund Activity

246 hedge funds and large institutions have $2.28B invested in Apellis Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 43 funds opening new positions, 108 increasing their positions, 69 reducing their positions, and 49 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
246
Holders Change
-8
Holders Change %
-3.15%
% of All Funds
3.3%
Holding in Top 10
4
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-33.33%
% of All Funds
0.05%
New
43
Increased
108
Reduced
69
Closed
49
Calls
$56.2M
Puts
$12.6M
Net Calls
+$43.6M
Net Calls Change
+$36.9M

Top Buyers

1
Marshall Wace
Marshall Wace
United Kingdom
$46.8M
2
DTC
Deep Track Capital
Connecticut
$121M
3
AQR Capital Management
AQR Capital Management
Connecticut
$103M
4
UBS Group
UBS Group
Switzerland
$82M
5
Amundi
Amundi
France
$28.6M

Top Sellers

1
Wellington Management Group
Wellington Management Group
Massachusetts
$155M
2
Fidelity Investments
Fidelity Investments
Massachusetts
$334K
3
Man Group
Man Group
United Kingdom
$0
4
OCA
Octagon Capital Advisors
New York
$15.6M
5
National Bank of Canada
National Bank of Canada
Quebec, Canada
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
Mirae Asset Global ETFs Holdings
126
Mirae Asset Global ETFs Holdings
Hong Kong
$710K +$198K +11,425 +39%
PFSRSONJ
127
Police & Firemen's Retirement System of New Jersey
New Jersey
$709K +$41.3K +2,385 +6%
WIA
128
Wealthedge Investment Advisors
New York
$668K +$668K +38,572 New
GC
129
Guggenheim Capital
Illinois
$666K +$53.7K +3,105 +9%
Mariner
130
Mariner
Kansas
$629K +$404K +23,326 +179%
Janus Henderson Group
131
Janus Henderson Group
United Kingdom
$595K – – –
Ohio Public Employees Retirement System (OPERS)
132
Ohio Public Employees Retirement System (OPERS)
Ohio
$579K +$8.57K +495 +2%
AllianceBernstein
133
AllianceBernstein
Tennessee
$553K -$225K -12,983 -29%
PCM
134
Prelude Capital Management
New York
$539K +$539K +31,139 New
Handelsbanken Fonder
135
Handelsbanken Fonder
Sweden
$523K -$6.93K -400 -1%
Focus Partners Wealth
136
Focus Partners Wealth
Massachusetts
$514K +$135K +7,793 +36%
CAPTRUST Financial Advisors
137
CAPTRUST Financial Advisors
North Carolina
$511K +$4.36K +252 +0.9%
Ensign Peak Advisors
138
Ensign Peak Advisors
Utah
$509K – – –
PA
139
Profund Advisors
Maryland
$496K -$121K -6,981 -20%
VRS
140
Virginia Retirement Systems
Virginia
$479K +$51.9K +3,000 +12%
First Trust Advisors
141
First Trust Advisors
Illinois
$459K -$2.99M -172,671 -87%
Universal-Beteiligungs- und Servicegesellschaft
142
Universal-Beteiligungs- und Servicegesellschaft
Germany
$437K +$158K +9,114 +56%
CUAMC
143
China Universal Asset Management Company
China
$437K +$1.16K +67 +0.3%
Parallax Volatility Advisers
144
Parallax Volatility Advisers
California
$423K -$67.6K -3,907 -14%
FPAS
145
Focus Partners Advisor Solutions
Missouri
$422K +$135K +7,783 +47%
Toronto Dominion Bank
146
Toronto Dominion Bank
Ontario, Canada
$406K -$2.4M -138,753 -86%
VIA
147
Virtus Investment Advisers
Connecticut
$399K +$210K +12,106 +110%
BFM
148
Boothbay Fund Management
New York
$398K – – –
SEI Investments
149
SEI Investments
Pennsylvania
$387K +$387K +22,359 New
ASRS
150
Arizona State Retirement System
Arizona
$381K +$42.3K +2,444 +13%
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6
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