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Apellis Pharmaceuticals
APLS

Overview Fund Activity

246 hedge funds and large institutions have $2.28B invested in Apellis Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 43 funds opening new positions, 108 increasing their positions, 69 reducing their positions, and 49 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
246
Holders Change
-8
Holders Change %
-3.15%
% of All Funds
3.3%
Holding in Top 10
4
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-33.33%
% of All Funds
0.05%
New
43
Increased
108
Reduced
69
Closed
49
Calls
$56.2M
Puts
$12.6M
Net Calls
+$43.6M
Net Calls Change
+$36.9M

Top Buyers

1
Marshall Wace
Marshall Wace
United Kingdom
$46.8M
2
DTC
Deep Track Capital
Connecticut
$121M
3
AQR Capital Management
AQR Capital Management
Connecticut
$103M
4
UBS Group
UBS Group
Switzerland
$82M
5
Amundi
Amundi
France
$28.6M

Top Sellers

1
Wellington Management Group
Wellington Management Group
Massachusetts
$155M
2
Fidelity Investments
Fidelity Investments
Massachusetts
$334K
3
Man Group
Man Group
United Kingdom
$0
4
OCA
Octagon Capital Advisors
New York
$15.6M
5
National Bank of Canada
National Bank of Canada
Quebec, Canada
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
UBS AM
51
UBS AM
Illinois
$5.23M +$1.37M +79,305 +36%
Barclays
52
Barclays
United Kingdom
$4.74M +$1.43M +82,675 +43%
Two Sigma Advisers
53
Two Sigma Advisers
New York
$4.45M +$1.13M +65,000 +34%
D.E. Shaw & Co
54
D.E. Shaw & Co
New York
$4.35M +$4.35M +251,069 New
Jane Street
55
Jane Street
New York
$4.26M -$171K -9,893 -4%
Bank of New York Mellon
56
Bank of New York Mellon
New York
$4.21M -$1.49M -85,846 -26%
JPMorgan Chase & Co
57
JPMorgan Chase & Co
New York
$4.06M -$3.27M -188,999 -45%
CM
58
Caption Management
Oklahoma
$4M +$3.79M +218,888 +1,824%
EP
59
Edgestream Partners
New Jersey
$3.78M -$396K -22,895 -9%
Goldman Sachs
60
Goldman Sachs
New York
$3.74M -$1.59M -91,710 -30%
FT
61
Fiduciary Trust
Massachusetts
$3.51M -$13.8K -800 -0.4%
Millennium Management
62
Millennium Management
New York
$3.5M -$4.32M -249,521 -55%
ACM
63
Aquatic Capital Management
Illinois
$3.06M -$678K -39,172 -18%
Invesco
64
Invesco
Georgia
$2.88M -$8.23M -475,262 -74%
YIH
65
Y-Intercept (HK)
Hong Kong
$2.84M +$2.33M +134,698 +455%
PP
66
PDT Partners
New York
$2.77M -$608K -35,107 -18%
Bank of Montreal
67
Bank of Montreal
Ontario, Canada
$2.76M +$18K +1,040 +0.7%
AG
68
Algert Global
California
$2.67M -$3.19M -184,500 -54%
Prudential Financial
69
Prudential Financial
New Jersey
$2.67M -$1.11M -63,870 -29%
VOYA Investment Management
70
VOYA Investment Management
Georgia
$2.61M +$436K +25,192 +20%
Rafferty Asset Management
71
Rafferty Asset Management
New York
$2.49M -$628K -36,282 -20%
Swiss National Bank
72
Swiss National Bank
Switzerland
$2.49M +$194K +11,200 +8%
SPIA
73
Steward Partners Investment Advisory
New York
$2.44M +$325K +18,800 +15%
Citigroup
74
Citigroup
New York
$2.4M -$4.82M -278,168 -67%
California Public Employees Retirement System
75
California Public Employees Retirement System
California
$2.33M +$137K +7,931 +6%
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