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Apellis Pharmaceuticals
APLS

Overview Fund Activity

246 hedge funds and large institutions have $2.28B invested in Apellis Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 43 funds opening new positions, 108 increasing their positions, 69 reducing their positions, and 49 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
246
Holders Change
-8
Holders Change %
-3.15%
% of All Funds
3.3%
Holding in Top 10
4
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-33.33%
% of All Funds
0.05%
New
43
Increased
108
Reduced
69
Closed
49
Calls
$56.2M
Puts
$12.6M
Net Calls
+$43.6M
Net Calls Change
+$36.9M

Top Buyers

1
Marshall Wace
Marshall Wace
United Kingdom
$46.8M
2
DTC
Deep Track Capital
Connecticut
$121M
3
AQR Capital Management
AQR Capital Management
Connecticut
$103M
4
UBS Group
UBS Group
Switzerland
$82M
5
Amundi
Amundi
France
$28.6M

Top Sellers

1
Wellington Management Group
Wellington Management Group
Massachusetts
$155M
2
Fidelity Investments
Fidelity Investments
Massachusetts
$334K
3
Man Group
Man Group
United Kingdom
$0
4
OCA
Octagon Capital Advisors
New York
$15.6M
5
National Bank of Canada
National Bank of Canada
Quebec, Canada
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
OCA
26
Octagon Capital Advisors
New York
$15.6M -$20.6M -1,190,500 -57%
CCM
27
Camber Capital Management
Massachusetts
$14.7M +$14.7M +850,000 New
Royal Bank of Canada
28
Royal Bank of Canada
Ontario, Canada
$13.8M +$45.9K +2,650 +0.3%
Ameriprise
29
Ameriprise
Minnesota
$13M +$4.91M +283,500 +61%
Bank of Nova Scotia
30
Bank of Nova Scotia
Ontario, Canada
$10.3M +$10.3M +594,812 New
JFG
31
Jefferies Financial Group
New York
$10M -$364K -21,050 -4%
JF
32
Jump Financial
Illinois
$9.67M +$5.07M +293,075 +110%
O
33
Ossiam
France
$9.62M +$9.62M +555,953 New
CLGM
34
Capitolis Liquid Global Markets
New York
$9.43M +$9.43M +544,600 New
WP
35
Woodline Partners
California
$9.19M +$5.4M +312,073 +143%
Northern Trust
36
Northern Trust
Illinois
$9.1M +$124K +7,188 +1%
Schroder Investment Management Group
37
Schroder Investment Management Group
United Kingdom
$8.41M +$4.02M +232,506 +92%
Hudson Bay Capital Management
38
Hudson Bay Capital Management
Connecticut
$8.22M +$2.84M +164,300 +53%
NL
39
Nuveen LLC
North Carolina
$8.12M -$398K -22,985 -5%
Voloridge Investment Management
40
Voloridge Investment Management
Florida
$8.11M +$3.72M +214,920 +85%
Citadel Advisors
41
Citadel Advisors
Florida
$7.66M +$3.78M +218,464 +97%
6CM
42
683 Capital Management
New York
$7.1M +$1.33M +77,000 +23%
Two Sigma Investments
43
Two Sigma Investments
New York
$7.04M +$2.49M +144,009 +55%
Pictet Asset Management
44
Pictet Asset Management
Switzerland
$6.07M +$584K +33,507 +11%
IC
45
IEQ Capital
California
$6.01M +$953K +55,065 +19%
Canada Pension Plan Investment Board
46
Canada Pension Plan Investment Board
Ontario, Canada
$5.83M -$12.3M -711,900 -68%
Squarepoint
47
Squarepoint
New York
$5.7M -$1.96M -113,401 -26%
Susquehanna International Group
48
Susquehanna International Group
Pennsylvania
$5.69M +$5.18M +299,221 +1,014%
TI
49
Trexquant Investment
Connecticut
$5.67M -$995K -57,501 -15%
IG
50
ING Group
Netherlands
$5.34M +$2.15M +124,100 +67%
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