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Apellis Pharmaceuticals
APLS

Overview Fund Activity

254 hedge funds and large institutions have $2.77B invested in Apellis Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 51 funds opening new positions, 90 increasing their positions, 75 reducing their positions, and 52 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
254
Holders Change
-4
Holders Change %
-1.55%
% of All Funds
3.45%
Holding in Top 10
6
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.08%
New
51
Increased
90
Reduced
75
Closed
52
Calls
$26.6M
Puts
$19.8M
Net Calls
+$6.76M
Net Calls Change
-$64.2M

Top Buyers

1
AQR Capital Management
AQR Capital Management
Connecticut
$89.2M
2
Bank of America
Bank of America
North Carolina
$68.5M
3
O
OrbiMed
New York
$31.3M
4
Canada Pension Plan Investment Board
Canada Pension Plan Investment Board
Ontario, Canada
$22.9M
5
Man Group
Man Group
United Kingdom
$22.5M

Top Sellers

1
CWM
CIBC World Markets
New York
$0
2
Point72 Asset Management
Point72 Asset Management
Connecticut
$0
3
OCA
Octagon Capital Advisors
New York
$45.8M
4
Toronto Dominion Bank
Toronto Dominion Bank
Ontario, Canada
$3.55M
5
LGM
Logos Global Management
California
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
CFD
251
Creative Financial Designs
Indiana
$109 +$109 +5 New
MCM
252
Manchester Capital Management
Vermont
$66 – – –
CWM
253
CIBC World Markets
New York
– -$41M -1,285,300 Closed
Point72 Asset Management
254
Point72 Asset Management
Connecticut
– -$40.5M -1,267,958 Closed
Norges Bank
255
Norges Bank
Norway
– -$34.7M -1,086,243 Closed
LGM
256
Logos Global Management
California
– -$16M -500,000 Closed
IHAM
257
Integral Health Asset Management
New York
– -$13.4M -420,000 Closed
MSE
258
MUFG Securities EMEA
United Kingdom
– -$9.51M -298,000 Closed
Renaissance Technologies
259
Renaissance Technologies
New York
– -$8.68M -271,913 Closed
IECM
260
Intrinsic Edge Capital Management
Illinois
– -$6.38M -200,000 Closed
PE
261
Point72 Europe
United Kingdom
– -$6.15M -192,694 Closed
CSS
262
Cubist Systematic Strategies
Connecticut
– -$6.12M -191,687 Closed
Capital Fund Management (CFM)
263
Capital Fund Management (CFM)
France
– -$3.87M -121,433 Closed
EAM
264
Exome Asset Management
New York
– -$3.81M -119,467 Closed
BPC
265
Banque Pictet & Cie
Switzerland
– -$3.1M -97,299 Closed
CCM
266
Cinctive Capital Management
New York
– -$2.78M -86,991 Closed
FCM
267
Fieldview Capital Management
Michigan
– -$1.96M -61,405 Closed
AAA
268
Affinity Asset Advisors
New York
– -$1.6M -50,000 Closed
TD Asset Management
269
TD Asset Management
Ontario, Canada
– -$1.23M -38,692 Closed
RAM
270
Readystate Asset Management
Illinois
– -$1.13M -35,561 Closed
PCM
271
Prelude Capital Management
New York
– -$997K -31,255 Closed
SCA
272
Sippican Capital Advisors
Massachusetts
– -$662K -20,753 Closed
D.E. Shaw & Co
273
D.E. Shaw & Co
New York
– -$638K -20,000 Closed
SC
274
Syon Capital
California
– -$621K -19,455 Closed
Creative Planning
275
Creative Planning
Kansas
– -$517K -16,214 Closed
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