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APLS

Apellis Pharmaceuticals
APLS

Delisted

APLS was delisted on the 13th of May, 2026.

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323 hedge funds and large institutions have $5.56B invested in Apellis Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 128 funds opening new positions, 89 increasing their positions, 72 reducing their positions, and 79 closing their positions.

New
Increased
Maintained
Reduced
Closed

200% more funds holding in top 10

Funds holding in top 10: 2 → 6 (+4)

75% more capital invested

Capital invested by funds: $3.17B → $5.56B (+$2.39B)

62% more first-time investments, than exits

New positions opened: 128 | Existing positions closed: 79

43% more call options, than puts

Call options by funds: $52.1M | Put options by funds: $36.5M

24% more repeat investments, than reductions

Existing positions increased: 89 | Existing positions reduced: 72

16% more funds holding

Funds holding: 279 → 323 (+44)

9.9% more ownership

Funds ownership: 99.89% → 109.78% (+9.9%)

Holders
323
Holders Change
+44
Holders Change %
+15.77%
% of All Funds
3.95%
Holding in Top 10
6
Holding in Top 10 Change
+4
Holding in Top 10 Change %
+200%
% of All Funds
0.07%
New
128
Increased
89
Reduced
72
Closed
79
Calls
$52.1M
Puts
$36.5M
Net Calls
+$15.7M
Net Calls Change
-$61.6M

Top Buyers

Rank Fund Capital Flow
1
BlackRock
BlackRock
New York
+$157M
2
PCM
Pentwater Capital Management
Florida
+$113M
3
Point72 Asset Management
Point72 Asset Management
Connecticut
+$77.3M
4
HI
HBK Investments
Texas
+$76.5M
5
State Street
State Street
Massachusetts
+$48.1M

Top Sellers

Rank Fund Capital Flow
1
Wellington Management Group
Wellington Management Group
Massachusetts
-$269M
2
PCH
Polar Capital Holdings
United Kingdom
-$93.1M
3
RI
RTW Investments
New York
-$85.8M
4
DTC
Deep Track Capital
Connecticut
-$69.3M
5
SL
Siren LLC
Connecticut
-$64.8M
Name Holding Trade Value Shares
Change 		Change in
Stake
TRSOTSOK
176
Teachers Retirement System of the State of Kentucky
Kentucky
$1.01M +$539K +25,000 New
Manulife (Manufacturers Life Insurance)
177
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$996K +$41.2K +1,913 +8%
TSS
178
Two Sigma Securities
New York
$957K +$512K +23,779 New
TH
179
Transmarket Holdings
Illinois
$949K +$508K +23,585 New
OPERF
180
Oregon Public Employees Retirement Fund
Oregon
$941K +$504K +23,400 New
EFM
181
E Fund Management
China
$913K +$489K +22,686 New
CUAMC
182
China Universal Asset Management Company
China
$913K +$44.5K +2,067 +10%
Fifth Third Bancorp
183
Fifth Third Bancorp
Ohio
$889K +$476K +22,102 New
MTCM
184
Mint Tower Capital Management
Netherlands
$885K +$474K +22,000 New
GI
185
GAMCO Investors
Connecticut
$845K +$453K +21,000 New
MSRPS
186
Maryland State Retirement & Pension System
Maryland
$837K +$449K +20,816 New
ASRS
187
Arizona State Retirement System
Arizona
$837K -$4.25K -197 -0.9%
Rockefeller Capital Management
188
Rockefeller Capital Management
New York
$830K +$434K +20,131 +4,002%
JC
189
JBF Capital
Colorado
$826K +$442K +20,532 New
SC
190
SummitTX Capital
Texas
$819K +$439K +20,351 New
CHAM
191
Clear Harbor Asset Management
Connecticut
$805K +$431K +20,000 New
Victory Capital Management
192
Victory Capital Management
Texas
$797K +$99.6K +4,620 +30%
Canada Pension Plan Investment Board
193
Canada Pension Plan Investment Board
Ontario, Canada
$789K -$4.37M -202,600 -91%
Vanguard Investments Australia
194
Vanguard Investments Australia
Australia
$774K +$415K +19,240 New
EGM
195
Engineers Gate Manager
New York
$772K +$414K +19,197 New
X
196
Xponance
Pennsylvania
$746K +$8.32K +386 +2%
New York State Teachers Retirement System (NYSTRS)
197
New York State Teachers Retirement System (NYSTRS)
New York
$736K +$394K +18,299 New
DWAM
198
Duncan Williams Asset Management
Tennessee
$684K – – –
KK
199
KLP Kapitalforvaltning
Norway
$652K – – –
STA
200
Summit Trail Advisors
New York
$645K +$46.8K +2,172 +16%
6 7
8
9 10

APLS Hedge Fund Activity: Q1 2026 in Review

323 of the 8,169 institutional investors tracked by Wall St. Rank reported a position in Apellis Pharmaceuticals (APLS) for Q1 2026, worth a combined $5.56B — up 75% from $3.17B a quarter earlier.

Buyers outnumbered sellers: 128 funds opened new APLS positions and 79 closed out — a net gain of 49 holders — while 89 added to existing stakes and 72 trimmed.

The largest buyer was BlackRock, adding an estimated $157M. The largest seller was Wellington Management Group, cutting an estimated $269M.

  • 323 institutional investors held Apellis Pharmaceuticals (APLS) as of Q1 2026, up from 279 in Q4 2025.
  • Funds reported $5.56B of Apellis Pharmaceuticals stock for Q1 2026, up 75% quarter-over-quarter.
  • 128 funds opened new Apellis Pharmaceuticals positions in Q1 2026 and 79 closed out, a net change of +49 holders.
  • The largest Apellis Pharmaceuticals buyer in Q1 2026 was BlackRock, an estimated $157M added.
  • The largest Apellis Pharmaceuticals seller in Q1 2026 was Wellington Management Group, an estimated $269M sold.

Based on aggregated 13F filings for Q1 2026.