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APLS

Apellis Pharmaceuticals

Delisted

APLS was delisted on the 13th of May, 2026.

211 hedge funds and large institutions have $4.13B invested in Apellis Pharmaceuticals in 2022 Q2 according to their latest regulatory filings, with 34 funds opening new positions, 100 increasing their positions, 53 reducing their positions, and 31 closing their positions.

New
Increased
Maintained
Reduced
Closed

150% more call options, than puts

Call options by funds: $55.6M | Put options by funds: $22.3M

89% more repeat investments, than reductions

Existing positions increased: 100 | Existing positions reduced: 53

10% more first-time investments, than exits

New positions opened: 34 | Existing positions closed: 31

0.44% less ownership

Funds ownership: 86.48%86.04% (-0.44%)

0% less funds holding

Funds holding: 212211 (-1)

9% less capital invested

Capital invested by funds: $4.55B → $4.13B (-$420M)

18% less funds holding in top 10

Funds holding in top 10: 119 (-2)

Holders
211
Holders Change
-1
Holders Change %
-0.47%
% of All Funds
3.55%
Holding in Top 10
9
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-18.18%
% of All Funds
0.15%
New
34
Increased
100
Reduced
53
Closed
31
Calls
$55.6M
Puts
$22.3M
Net Calls
+$33.3M
Net Calls Change
+$34M
Name Holding Trade Value Shares
Change
Change in
Stake
D.E. Shaw & Co
176
D.E. Shaw & Co
New York
$207K -$1.3M -28,464 -86%
IAS
177
IMA Advisory Services
Colorado
$181K
Amundi
178
Amundi
France
$178K
Canada Life
179
Canada Life
Manitoba, Canada
$169K
DCM
180
Dupont Capital Management
Delaware
$143K
SAM
181
S.A. Mason
Michigan
$143K +$18.9K +415 +15%
UID
182
Union Investments & Development
Israel
$136K
CAC
183
Cowen and Company
New York
$135K +$80.3K +1,762 +143%
Osaic Holdings
184
Osaic Holdings
Arizona
$120K +$2.83K +62 +2%
JAMONY
185
Jacob Asset Management of New York
California
$75K -$75K -1,645 -50%
QPBE
186
Quintet Private Bank (Europe)
Luxembourg
$68.2K +$34.9K +765 New
HIA
187
Harbor Investment Advisory
Maryland
$60K +$10K +220 +20%
SM
188
SG3 Management
Puerto Rico
$52K +$52.7K +1,155 New
IBT
189
International Biotechnology Trust
United Kingdom
$32.5K -$1.41M -31,030 -95%
Daiwa Securities Group
190
Daiwa Securities Group
Japan
$18K +$4.51K +99 +33%
US Bancorp
191
US Bancorp
Minnesota
$17K -$34K -745 -67%
TWA
192
TCI Wealth Advisors
Arizona
$14K
CA
193
CoreCap Advisors
Michigan
$14K +$13.7K +300 New
Baillie Gifford & Co
194
Baillie Gifford & Co
United Kingdom
$13K +$12.9K +283 New
C
195
Covestor
United Kingdom
$12K -$46 -1 -0.4%
BPC
196
Banque Pictet & Cie
Switzerland
$8.12K -$441K -9,673 -5%
IUHSA
197
Itau Unibanco Holding S.A.
Brazil
$8K +$456 +10 +6%
Bank of Montreal
198
Bank of Montreal
Ontario, Canada
$7.81K +$821 +18 +0%
SOW
199
State of Wyoming
Wyoming
$7K +$6.84K +150 New
LC
200
Lindbrook Capital
California
$5K +$365 +8 +9%

APLS Hedge Fund Activity: Q2 2022 in Review

211 of the 5,937 institutional investors tracked by Wall St. Rank reported a position in Apellis Pharmaceuticals (APLS) for Q2 2022, worth a combined $4.13B — down 9.2% from $4.55B a quarter earlier.

Buyers outnumbered sellers: 34 funds opened new APLS positions and 31 closed out — a net gain of 3 holders — while 100 added to existing stakes and 53 trimmed.

The largest buyer was BlackRock, adding an estimated $39.9M. The largest seller was Wellington Management Group, cutting an estimated $121M.

  • 211 institutional investors held Apellis Pharmaceuticals (APLS) as of Q2 2022, down from 212 in Q1 2022.
  • Funds reported $4.13B of Apellis Pharmaceuticals stock for Q2 2022, down 9.2% quarter-over-quarter.
  • 34 funds opened new Apellis Pharmaceuticals positions in Q2 2022 and 31 closed out, a net change of +3 holders.
  • The largest Apellis Pharmaceuticals buyer in Q2 2022 was BlackRock, an estimated $39.9M added.
  • The largest Apellis Pharmaceuticals seller in Q2 2022 was Wellington Management Group, an estimated $121M sold.

Based on aggregated 13F filings for Q2 2022.