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APLS

Apellis Pharmaceuticals

Delisted

APLS was delisted on the 13th of May, 2026.

323 hedge funds and large institutions have $5.56B invested in Apellis Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 128 funds opening new positions, 89 increasing their positions, 72 reducing their positions, and 79 closing their positions.

New
Increased
Maintained
Reduced
Closed

200% more funds holding in top 10

Funds holding in top 10: 26 (+4)

75% more capital invested

Capital invested by funds: $3.17B → $5.56B (+$2.39B)

62% more first-time investments, than exits

New positions opened: 128 | Existing positions closed: 79

43% more call options, than puts

Call options by funds: $52.1M | Put options by funds: $36.5M

24% more repeat investments, than reductions

Existing positions increased: 89 | Existing positions reduced: 72

16% more funds holding

Funds holding: 279323 (+44)

9.9% more ownership

Funds ownership: 99.89%109.78% (+9.9%)

Holders
323
Holders Change
+44
Holders Change %
+15.77%
% of All Funds
3.95%
Holding in Top 10
6
Holding in Top 10 Change
+4
Holding in Top 10 Change %
+200%
% of All Funds
0.07%
New
128
Increased
89
Reduced
72
Closed
79
Calls
$52.1M
Puts
$36.5M
Net Calls
+$15.7M
Net Calls Change
-$61.6M
Name Holding Trade Value Shares
Change
Change in
Stake
SFM
76
Sphera Funds Management
Israel
$8.65M -$777K -36,047 -14%
TI
77
Trexquant Investment
Connecticut
$8.26M +$229K +10,627 +5%
GCIA
78
Gabelli & Co Investment Advisers
New York
$8.07M +$4.32M +200,600 New
Pictet Asset Management
79
Pictet Asset Management
Switzerland
$7.56M +$774K +35,937 +9%
D.E. Shaw & Co
80
D.E. Shaw & Co
New York
$7.52M -$5.66M -262,823 -58%
Ameriprise
81
Ameriprise
Minnesota
$7.39M -$8.75M -406,019 -69%
BFM
82
Boothbay Fund Management
New York
$7.38M +$3.49M +162,107 +757%
Rafferty Asset Management
83
Rafferty Asset Management
New York
$7.26M +$194K +9,015 +5%
FT
84
Fiduciary Trust
Massachusetts
$7.25M -$2K -93 -0.1%
UBS AM
85
UBS AM
Illinois
$7.24M +$22.9K +1,065 +0.6%
GLAM
86
Gardner Lewis Asset Management
Pennsylvania
$6.64M +$3.56M +165,000 New
RSCM
87
Rock Springs Capital Management
Maryland
$6.55M +$264K +12,250 +8%
Mackenzie Financial
88
Mackenzie Financial
Ontario, Canada
$6.17M +$1.23M +57,119 +59%
PMAM
89
Picton Mahoney Asset Management
Ontario, Canada
$6.03M +$3.23M +150,000 New
Swiss National Bank
90
Swiss National Bank
Switzerland
$6.01M
EF
91
Empowered Funds
Pennsylvania
$5.96M +$2.9M +134,657 +1,006%
AA
92
AQR Arbitrage
Connecticut
$5.9M +$3.16M +146,604 New
CCM
93
Chicago Capital Management
Illinois
$5.76M +$4.09M +190,000 New
SC
94
Slotnik Capital
Texas
$5.43M +$2.91M +135,000 New
TS
95
Twin Securities
New York
$5.13M +$2.75M +127,440 New
Royal Bank of Canada
96
Royal Bank of Canada
Ontario, Canada
$5.1M +$819K +38,014 +43%
SSA
97
Schonfeld Strategic Advisors
New York
$4.98M +$2.67M +123,824 New
QCM
98
Quantinno Capital Management
New York
$4.88M +$1.93M +89,507 +282%
WIC
99
Water Island Capital
New York
$4.85M +$2.6M +120,500 New
PCM
100
Prelude Capital Management
New York
$4.48M +$1.57M +72,947 +189%

APLS Hedge Fund Activity: Q1 2026 in Review

323 of the 8,169 institutional investors tracked by Wall St. Rank reported a position in Apellis Pharmaceuticals (APLS) for Q1 2026, worth a combined $5.56B — up 75% from $3.17B a quarter earlier.

Buyers outnumbered sellers: 128 funds opened new APLS positions and 79 closed out — a net gain of 49 holders — while 89 added to existing stakes and 72 trimmed.

The largest buyer was BlackRock, adding an estimated $157M. The largest seller was Wellington Management Group, cutting an estimated $269M.

  • 323 institutional investors held Apellis Pharmaceuticals (APLS) as of Q1 2026, up from 279 in Q4 2025.
  • Funds reported $5.56B of Apellis Pharmaceuticals stock for Q1 2026, up 75% quarter-over-quarter.
  • 128 funds opened new Apellis Pharmaceuticals positions in Q1 2026 and 79 closed out, a net change of +49 holders.
  • The largest Apellis Pharmaceuticals buyer in Q1 2026 was BlackRock, an estimated $157M added.
  • The largest Apellis Pharmaceuticals seller in Q1 2026 was Wellington Management Group, an estimated $269M sold.

Based on aggregated 13F filings for Q1 2026.