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APLS

Apellis Pharmaceuticals

Delisted

APLS was delisted on the 13th of May, 2026.

250 hedge funds and large institutions have $6.65B invested in Apellis Pharmaceuticals in 2022 Q3 according to their latest regulatory filings, with 67 funds opening new positions, 93 increasing their positions, 65 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

148% more first-time investments, than exits

New positions opened: 67 | Existing positions closed: 27

61% more capital invested

Capital invested by funds: $4.13B → $6.65B (+$2.52B)

43% more repeat investments, than reductions

Existing positions increased: 93 | Existing positions reduced: 65

18% more funds holding

Funds holding: 211250 (+39)

11% more funds holding in top 10

Funds holding in top 10: 910 (+1)

2.73% more ownership

Funds ownership: 86.04%88.77% (+2.7%)

17% less call options, than puts

Call options by funds: $92M | Put options by funds: $111M

Holders
250
Holders Change
+39
Holders Change %
+18.48%
% of All Funds
4.31%
Holding in Top 10
10
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+11.11%
% of All Funds
0.17%
New
67
Increased
93
Reduced
65
Closed
27
Calls
$92M
Puts
$111M
Net Calls
-$19.4M
Net Calls Change
-$52.7M
Name Holding Trade Value Shares
Change
Change in
Stake
RhumbLine Advisers
76
RhumbLine Advisers
Massachusetts
$8.41M +$784K +13,256 +12%
PHS
77
PFM Health Sciences
California
$8.32M +$7.21M +121,880 New
BNP Paribas Financial Markets
78
BNP Paribas Financial Markets
France
$7.88M +$5.64M +95,294 +475%
Two Sigma Investments
79
Two Sigma Investments
New York
$7.75M +$6.71M +113,472 New
California State Teachers Retirement System (CalSTRS)
80
California State Teachers Retirement System (CalSTRS)
California
$7.54M +$281K +4,746 +4%
Voloridge Investment Management
81
Voloridge Investment Management
Florida
$7.34M +$6.36M +107,452 New
PI
82
Putnam Investments
Massachusetts
$7.23M +$6.26M +105,803 New
TRSOTSOK
83
Teachers Retirement System of the State of Kentucky
Kentucky
$7.09M +$6.14M +103,802 New
Rafferty Asset Management
84
Rafferty Asset Management
New York
$7.01M +$573K +9,683 +10%
Squarepoint
85
Squarepoint
New York
$6.9M +$3M +50,705 +101%
Citigroup
86
Citigroup
New York
$6.68M -$244K -4,128 -4%
Manulife (Manufacturers Life Insurance)
87
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$6.19M -$224K -3,792 -4%
PFM
88
Privium Fund Management
Netherlands
$6.06M -$2.66M -45,000 -33%
Russell Investments Group
89
Russell Investments Group
United Kingdom
$6.02M +$2.37M +40,082 +83%
1832 Asset Management
90
1832 Asset Management
Ontario, Canada
$6.02M +$5.21M +88,100 New
SSA
91
Schonfeld Strategic Advisors
New York
$5.78M -$770K -13,017 -13%
Dimensional Fund Advisors
92
Dimensional Fund Advisors
Texas
$5.64M +$4.89M +82,594 New
Canada Pension Plan Investment Board
93
Canada Pension Plan Investment Board
Ontario, Canada
$5.62M -$408K -6,900 -8%
State of Wisconsin Investment Board
94
State of Wisconsin Investment Board
Wisconsin
$5.54M -$114K -1,926 -2%
Legal & General Group
95
Legal & General Group
United Kingdom
$5.51M -$78.8K -1,332 -2%
Parallax Volatility Advisers
96
Parallax Volatility Advisers
California
$5.27M +$1.72M +29,090 +61%
CS
97
Credit Suisse
Switzerland
$5.25M +$716K +12,108 +19%
Royal Bank of Canada
98
Royal Bank of Canada
Ontario, Canada
$5.07M -$471K -7,953 -10%
IHAM
99
Integral Health Asset Management
New York
$4.78M -$1.72M -29,150 -29%
UBS AM
100
UBS AM
Illinois
$4.72M -$16.7M -282,466 -80%

APLS Hedge Fund Activity: Q3 2022 in Review

250 of the 5,806 institutional investors tracked by Wall St. Rank reported a position in Apellis Pharmaceuticals (APLS) for Q3 2022, worth a combined $6.65B — up 61% from $4.13B a quarter earlier.

Buyers outnumbered sellers: 67 funds opened new APLS positions and 27 closed out — a net gain of 40 holders — while 93 added to existing stakes and 65 trimmed.

The largest buyer was Artal Group, opening a new position worth an estimated $59.2M. The largest seller was T. Rowe Price Associates, cutting an estimated $315M.

  • 250 institutional investors held Apellis Pharmaceuticals (APLS) as of Q3 2022, up from 211 in Q2 2022.
  • Funds reported $6.65B of Apellis Pharmaceuticals stock for Q3 2022, up 61% quarter-over-quarter.
  • 67 funds opened new Apellis Pharmaceuticals positions in Q3 2022 and 27 closed out, a net change of +40 holders.
  • The largest Apellis Pharmaceuticals buyer in Q3 2022 was Artal Group, an estimated $59.2M added.
  • The largest Apellis Pharmaceuticals seller in Q3 2022 was T. Rowe Price Associates, an estimated $315M sold.

Based on aggregated 13F filings for Q3 2022.