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APLS

Apellis Pharmaceuticals

Delisted

APLS was delisted on the 13th of May, 2026.

323 hedge funds and large institutions have $5.56B invested in Apellis Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 128 funds opening new positions, 89 increasing their positions, 72 reducing their positions, and 79 closing their positions.

New
Increased
Maintained
Reduced
Closed

200% more funds holding in top 10

Funds holding in top 10: 26 (+4)

75% more capital invested

Capital invested by funds: $3.17B → $5.56B (+$2.39B)

62% more first-time investments, than exits

New positions opened: 128 | Existing positions closed: 79

43% more call options, than puts

Call options by funds: $52.1M | Put options by funds: $36.5M

24% more repeat investments, than reductions

Existing positions increased: 89 | Existing positions reduced: 72

16% more funds holding

Funds holding: 279323 (+44)

9.9% more ownership

Funds ownership: 99.89%109.78% (+9.9%)

Holders
323
Holders Change
+44
Holders Change %
+15.77%
% of All Funds
3.95%
Holding in Top 10
6
Holding in Top 10 Change
+4
Holding in Top 10 Change %
+200%
% of All Funds
0.07%
New
128
Increased
89
Reduced
72
Closed
79
Calls
$52.1M
Puts
$36.5M
Net Calls
+$15.7M
Net Calls Change
-$61.6M
Name Holding Trade Value Shares
Change
Change in
Stake
S
301
Sachetta
Massachusetts
$2.41K
TPCW
302
TD Private Client Wealth
New York
$2.25K
FMII
303
Farmers & Merchants Investments Inc
Nebraska
$2.01K +$1.08K +50 New
CAL
304
Capital Analysts LLC
Pennsylvania
$2K
SAM
305
Smartleaf Asset Management
Massachusetts
$1.83K +$1.01K +47 +78%
NB
306
NBT Bank
New York
$1.81K +$970 +45 New
MCM
307
Manchester Capital Management
Vermont
$1.13K
HI
308
Horizon Investments
North Carolina
$966 +$517 +24 New
TPWA
309
Twin Peaks Wealth Advisors
California
$966 +$517 +24 New
SPIA
310
Steward Partners Investment Advisory
New York
$925 -$1.76M -81,675 -100%
CT
311
Clearstead Trust
Maine
$725 -$366 -17 -49%
CMA
312
Cedar Mountain Advisors
Oregon
$724 +$388 +18 New
TWD
313
True Wealth Design
Ohio
$644 -$3.73K -173 -92%
RFP
314
Root Financial Partners
California
$483 +$259 +12 New
KFAS
315
Keating Financial Advisory Services
Kansas
$443 +$237 +11 New
MCM
316
MV Capital Management
Maryland
$242 -$65 -3 -33%
WA
317
WPG Advisers
Maryland
$201
FISPB
318
Fideuram - Intesa Sanpaolo Private Banking
$161
DF
319
Dunhill Financial
United Kingdom
$84
HFS
320
Hughes Financial Services
Virginia
$40 -$1.51K -70 -99%
IAAG
321
Innovative Asset Advisors Group
Connecticut
$40 +$22 +1 New
PCH
322
Polar Capital Holdings
United Kingdom
-$93.1M -3,706,510 Closed
SL
323
Siren LLC
Connecticut
-$64.8M -2,578,396 Closed
O
324
OrbiMed
New York
-$61M -2,429,868 Closed
Jennison Associates
325
Jennison Associates
New York
-$37.8M -1,504,299 Closed

APLS Hedge Fund Activity: Q1 2026 in Review

323 of the 8,169 institutional investors tracked by Wall St. Rank reported a position in Apellis Pharmaceuticals (APLS) for Q1 2026, worth a combined $5.56B — up 75% from $3.17B a quarter earlier.

Buyers outnumbered sellers: 128 funds opened new APLS positions and 79 closed out — a net gain of 49 holders — while 89 added to existing stakes and 72 trimmed.

The largest buyer was BlackRock, adding an estimated $157M. The largest seller was Wellington Management Group, cutting an estimated $269M.

  • 323 institutional investors held Apellis Pharmaceuticals (APLS) as of Q1 2026, up from 279 in Q4 2025.
  • Funds reported $5.56B of Apellis Pharmaceuticals stock for Q1 2026, up 75% quarter-over-quarter.
  • 128 funds opened new Apellis Pharmaceuticals positions in Q1 2026 and 79 closed out, a net change of +49 holders.
  • The largest Apellis Pharmaceuticals buyer in Q1 2026 was BlackRock, an estimated $157M added.
  • The largest Apellis Pharmaceuticals seller in Q1 2026 was Wellington Management Group, an estimated $269M sold.

Based on aggregated 13F filings for Q1 2026.