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Alto Neuroscience
ANRO

77 hedge funds and large institutions have $67.4M invested in Alto Neuroscience in 2025 Q3 according to their latest regulatory filings, with 9 funds opening new positions, 18 increasing their positions, 26 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed

100% more funds holding in top 10

Funds holding in top 10: 1 → 2 (+1)

77% more capital invested

Capital invested by funds: $38.1M → $67.4M (+$29.3M)

3% more call options, than puts

Call options by funds: $82K | Put options by funds: $80K

2% less ownership

Funds ownership: 63.89% → 61.89% (-2%)

4% less funds holding

Funds holding: 80 → 77 (-3)

25% less first-time investments, than exits

New positions opened: 9 | Existing positions closed: 12

31% less repeat investments, than reductions

Existing positions increased: 18 | Existing positions reduced: 26

Holders
77
Holders Change
-3
Holders Change %
-3.75%
% of All Funds
1.01%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.03%
New
9
Increased
18
Reduced
26
Closed
12
Calls
$82K
Puts
$80K
Net Calls
+$2K
Net Calls Change
+$35K

Top Buyers

Rank Fund Capital Flow
1
PA
Perceptive Advisors
New York
+$515K
2
Susquehanna International Group
Susquehanna International Group
Pennsylvania
+$314K
3
Two Sigma Investments
Two Sigma Investments
New York
+$238K
4
Two Sigma Advisers
Two Sigma Advisers
New York
+$224K
5
Renaissance Technologies
Renaissance Technologies
New York
+$136K

Top Sellers

Rank Fund Capital Flow
1
UBS Group
UBS Group
Switzerland
-$959K
2
BlackRock
BlackRock
New York
-$643K
3
Marshall Wace
Marshall Wace
United Kingdom
-$372K
4
Charles Schwab
Charles Schwab
California
-$254K
5
Goldman Sachs
Goldman Sachs
New York
-$251K
Name Holding Trade Value Shares
Change 		Change in
Stake
AWG
1
Alpha Wave Global
New York
$14.9M – – –
AC
2
Armistice Capital
New York
$6.58M +$39.8K +12,000 +0.7%
Point72 Asset Management
3
Point72 Asset Management
Connecticut
$5.36M +$8.89K +2,682 +0.2%
Franklin Resources
4
Franklin Resources
California
$4.67M – – –
Vanguard Group
5
Vanguard Group
Pennsylvania
$4.44M +$68.6K +20,702 +2%
VPC
6
Vestal Point Capital
New York
$3.82M – – –
Marshall Wace
7
Marshall Wace
United Kingdom
$3.32M -$372K -112,182 -12%
7IH
8
72 Investment Holdings
Connecticut
$2.68M – – –
Alkeon Capital Management
9
Alkeon Capital Management
New York
$1.92M – – –
Northern Trust
10
Northern Trust
Illinois
$1.85M -$6.83K -2,059 -0.4%
IHAM
11
Integral Health Asset Management
New York
$1.61M – – –
BlackRock
12
BlackRock
New York
$1.48M -$643K -193,969 -35%
Millennium Management
13
Millennium Management
New York
$1.27M +$42.8K +12,896 +4%
PLC
14
Peapod Lane Capital
New York
$1.14M +$10.3K +3,106 +1%
AIC
15
AWM Investment Company
New York
$1.13M – – –
O
16
OrbiMed
New York
$1M – – –
Geode Capital Management
17
Geode Capital Management
Massachusetts
$957K +$27.1K +8,179 +4%
AC
18
Almitas Capital
California
$784K – – –
Susquehanna International Group
19
Susquehanna International Group
Pennsylvania
$626K +$314K +94,613 +155%
PA
20
Perceptive Advisors
New York
$625K +$515K +155,366 New
Two Sigma Advisers
21
Two Sigma Advisers
New York
$603K +$224K +67,700 +82%
UBS Group
22
UBS Group
Switzerland
$559K -$959K -289,185 -68%
Stifel Financial
23
Stifel Financial
Missouri
$490K -$16.1K -4,853 -4%
Two Sigma Investments
24
Two Sigma Investments
New York
$469K +$238K +71,844 +161%
IC
25
Ikarian Capital
Texas
$442K – – –
1
2 3 4

ANRO Hedge Fund Activity: Q3 2025 in Review

77 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Alto Neuroscience (ANRO) for Q3 2025, worth a combined $67.4M — up 77% from $38.1M a quarter earlier.

Sellers outnumbered buyers: 12 funds closed out of ANRO and 9 opened new positions — a net loss of 3 holders — while 26 trimmed existing stakes and 18 added.

The largest buyer was Perceptive Advisors, opening a new position worth an estimated $515K. The largest seller was UBS Group, cutting an estimated $959K.

  • 77 institutional investors held Alto Neuroscience (ANRO) as of Q3 2025, down from 80 in Q2 2025.
  • Funds reported $67.4M of Alto Neuroscience stock for Q3 2025, up 77% quarter-over-quarter.
  • 9 funds opened new Alto Neuroscience positions in Q3 2025 and 12 closed out, a net change of -3 holders.
  • The largest Alto Neuroscience buyer in Q3 2025 was Perceptive Advisors, an estimated $515K added.
  • The largest Alto Neuroscience seller in Q3 2025 was UBS Group, an estimated $959K sold.

Based on aggregated 13F filings for Q3 2025.