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Alto Neuroscience
ANRO

77 hedge funds and large institutions have $67.4M invested in Alto Neuroscience in 2025 Q3 according to their latest regulatory filings, with 9 funds opening new positions, 18 increasing their positions, 26 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed

100% more funds holding in top 10

Funds holding in top 10: 1 → 2 (+1)

77% more capital invested

Capital invested by funds: $38.1M → $67.4M (+$29.3M)

3% more call options, than puts

Call options by funds: $82K | Put options by funds: $80K

2% less ownership

Funds ownership: 63.89% → 61.89% (-2%)

4% less funds holding

Funds holding: 80 → 77 (-3)

25% less first-time investments, than exits

New positions opened: 9 | Existing positions closed: 12

31% less repeat investments, than reductions

Existing positions increased: 18 | Existing positions reduced: 26

Holders
77
Holders Change
-3
Holders Change %
-3.75%
% of All Funds
1.01%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.03%
New
9
Increased
18
Reduced
26
Closed
12
Calls
$82K
Puts
$80K
Net Calls
+$2K
Net Calls Change
+$35K

Top Buyers

Rank Fund Capital Flow
1
PA
Perceptive Advisors
New York
+$515K
2
Susquehanna International Group
Susquehanna International Group
Pennsylvania
+$314K
3
Two Sigma Investments
Two Sigma Investments
New York
+$238K
4
Two Sigma Advisers
Two Sigma Advisers
New York
+$224K
5
Renaissance Technologies
Renaissance Technologies
New York
+$136K

Top Sellers

Rank Fund Capital Flow
1
UBS Group
UBS Group
Switzerland
-$959K
2
BlackRock
BlackRock
New York
-$643K
3
Marshall Wace
Marshall Wace
United Kingdom
-$372K
4
Charles Schwab
Charles Schwab
California
-$254K
5
Goldman Sachs
Goldman Sachs
New York
-$251K
Name Holding Trade Value Shares
Change 		Change in
Stake
State Street
26
State Street
Massachusetts
$415K -$5.14K -1,549 -1%
Goldman Sachs
27
Goldman Sachs
New York
$363K -$251K -75,836 -46%
LNWWM
28
Laird Norton Wetherby Wealth Management
California
$338K – – –
BCM
29
Bridgeway Capital Management
Texas
$312K +$78.1K +23,553 +44%
Renaissance Technologies
30
Renaissance Technologies
New York
$305K +$136K +41,072 +118%
SCM
31
SCS Capital Management
Massachusetts
$268K – – –
IC
32
IEQ Capital
California
$253K -$7.33K -2,210 -3%
Morgan Stanley
33
Morgan Stanley
New York
$245K -$11.9K -3,594 -6%
T. Rowe Price Associates
34
T. Rowe Price Associates
Maryland
$239K – – –
Jane Street
35
Jane Street
New York
$194K -$201K -60,654 -56%
CFG
36
Citizens Financial Group
Rhode Island
$161K +$21.2K +6,394 +19%
Citadel Advisors
37
Citadel Advisors
Florida
$149K +$123K +37,152 New
Allianz Asset Management
38
Allianz Asset Management
Germany
$149K – – –
QCM
39
Quantinno Capital Management
New York
$143K – – –
BFM
40
Boothbay Fund Management
New York
$131K – – –
AQR Capital Management
41
AQR Capital Management
Connecticut
$122K -$153K -46,100 -60%
Brown Advisory
42
Brown Advisory
Maryland
$101K – – –
Squarepoint
43
Squarepoint
New York
$91.7K -$150K -45,132 -66%
UOTTAIMCU
44
University of Texas/Texas AM Investment Management Co (UTIMCO)
Texas
$89.1K – – –
BCM
45
Bowie Capital Management
Texas
$78.3K – – –
VPIM
46
Vanguard Personalized Indexing Management
California
$68.5K +$6.81K +2,055 +14%
XT
47
XTX Topco
Cayman Islands
$63.3K +$52.2K +15,746 New
Acadian Asset Management
48
Acadian Asset Management
Massachusetts
$58K -$39.6K -11,954 -45%
Ameriprise
49
Ameriprise
Minnesota
$54.2K -$315 -95 -0.7%
PCM
50
Prelude Capital Management
New York
$45.8K – – –
1
2
3 4

ANRO Hedge Fund Activity: Q3 2025 in Review

77 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Alto Neuroscience (ANRO) for Q3 2025, worth a combined $67.4M — up 77% from $38.1M a quarter earlier.

Sellers outnumbered buyers: 12 funds closed out of ANRO and 9 opened new positions — a net loss of 3 holders — while 26 trimmed existing stakes and 18 added.

The largest buyer was Perceptive Advisors, opening a new position worth an estimated $515K. The largest seller was UBS Group, cutting an estimated $959K.

  • 77 institutional investors held Alto Neuroscience (ANRO) as of Q3 2025, down from 80 in Q2 2025.
  • Funds reported $67.4M of Alto Neuroscience stock for Q3 2025, up 77% quarter-over-quarter.
  • 9 funds opened new Alto Neuroscience positions in Q3 2025 and 12 closed out, a net change of -3 holders.
  • The largest Alto Neuroscience buyer in Q3 2025 was Perceptive Advisors, an estimated $515K added.
  • The largest Alto Neuroscience seller in Q3 2025 was UBS Group, an estimated $959K sold.

Based on aggregated 13F filings for Q3 2025.