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Alto Neuroscience
ANRO

80 hedge funds and large institutions have $38.1M invested in Alto Neuroscience in 2025 Q2 according to their latest regulatory filings, with 20 funds opening new positions, 21 increasing their positions, 23 reducing their positions, and 23 closing their positions.

New
Increased
Maintained
Reduced
Closed

9% less repeat investments, than reductions

Existing positions increased: 21 | Existing positions reduced: 23

4% less funds holding

Funds holding: 83 → 80 (-3)

13% less first-time investments, than exits

New positions opened: 20 | Existing positions closed: 23

13.12% less ownership

Funds ownership: 77.01% → 63.89% (-13%)

15% less capital invested

Capital invested by funds: $45M → $38.1M (-$6.98M)

50% less funds holding in top 10

Funds holding in top 10: 2 → 1 (-1)

75% less call options, than puts

Call options by funds: $11K | Put options by funds: $44K

Holders
80
Holders Change
-3
Holders Change %
-3.61%
% of All Funds
1.05%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
20
Increased
21
Reduced
23
Closed
23
Calls
$11K
Puts
$44K
Net Calls
-$33K
Net Calls Change
-$20K

Top Buyers

Rank Fund Capital Flow
1
Millennium Management
Millennium Management
New York
+$682K
2
PLC
Peapod Lane Capital
New York
+$664K
3
Jane Street
Jane Street
New York
+$259K
4
Point72 Asset Management
Point72 Asset Management
Connecticut
+$213K
5
Marshall Wace
Marshall Wace
United Kingdom
+$201K

Top Sellers

Rank Fund Capital Flow
1
Fidelity Investments
Fidelity Investments
Massachusetts
-$3.01M
2
BlackRock
BlackRock
New York
-$2.14M
3
AIC
AWM Investment Company
New York
-$1.48M
4
Citadel Advisors
Citadel Advisors
Florida
-$1.19M
5
WP
Woodline Partners
California
-$777K
Name Holding Trade Value Shares
Change 		Change in
Stake
LNWWM
26
Laird Norton Wetherby Wealth Management
California
$185K +$200K +84,162 New
Two Sigma Advisers
27
Two Sigma Advisers
New York
$181K +$162K +67,900 +475%
AQR Capital Management
28
AQR Capital Management
Connecticut
$168K +$125K +52,413 +217%
Squarepoint
29
Squarepoint
New York
$149K +$122K +51,384 +310%
SCM
30
SCS Capital Management
Massachusetts
$147K – – –
IC
31
IEQ Capital
California
$143K – – –
Morgan Stanley
32
Morgan Stanley
New York
$142K +$42.4K +17,823 +38%
Susquehanna International Group
33
Susquehanna International Group
Pennsylvania
$134K +$78.7K +33,061 +118%
T. Rowe Price Associates
34
T. Rowe Price Associates
Maryland
$131K +$13.1K +5,499 +10%
BCM
35
Bridgeway Capital Management
Texas
$119K +$59.5K +25,000 +86%
Two Sigma Investments
36
Two Sigma Investments
New York
$98.4K +$44.2K +18,593 +71%
CF
37
Cantor Fitzgerald
New York
$88K – – –
YIH
38
Y-Intercept (HK)
Hong Kong
$84.9K +$91.8K +38,597 New
Allianz Asset Management
39
Allianz Asset Management
Germany
$81.4K – – –
QCM
40
Quantinno Capital Management
New York
$78.3K +$84.7K +35,579 New
Renaissance Technologies
41
Renaissance Technologies
New York
$76.3K +$82.6K +34,700 New
CFG
42
Citizens Financial Group
Rhode Island
$73.9K -$11.9K -5,000 -13%
BFM
43
Boothbay Fund Management
New York
$71.4K -$56.3K -23,660 -42%
Acadian Asset Management
44
Acadian Asset Management
Massachusetts
$57K +$63K +26,477 New
Brown Advisory
45
Brown Advisory
Maryland
$55K – – –
UOTTAIMCU
46
University of Texas/Texas AM Investment Management Co (UTIMCO)
Texas
$48.8K – – –
JG
47
Jain Global
New York
$46.6K +$50.4K +21,171 New
AC
48
AlphaCore Capital
California
$44K +$23.8K +10,000 +100%
BCM
49
Bowie Capital Management
Texas
$42.9K – – –
VPIM
50
Vanguard Personalized Indexing Management
California
$33K +$35.7K +14,990 New
1
2
3 4 5

ANRO Hedge Fund Activity: Q2 2025 in Review

80 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Alto Neuroscience (ANRO) for Q2 2025, worth a combined $38.1M — down 15% from $45M a quarter earlier.

Sellers outnumbered buyers: 23 funds closed out of ANRO and 20 opened new positions — a net loss of 3 holders — while 23 trimmed existing stakes and 21 added.

The largest buyer was Millennium Management, adding an estimated $682K. The largest seller was Fidelity Investments, cutting an estimated $3.01M.

  • 80 institutional investors held Alto Neuroscience (ANRO) as of Q2 2025, down from 83 in Q1 2025.
  • Funds reported $38.1M of Alto Neuroscience stock for Q2 2025, down 15% quarter-over-quarter.
  • 20 funds opened new Alto Neuroscience positions in Q2 2025 and 23 closed out, a net change of -3 holders.
  • The largest Alto Neuroscience buyer in Q2 2025 was Millennium Management, an estimated $682K added.
  • The largest Alto Neuroscience seller in Q2 2025 was Fidelity Investments, an estimated $3.01M sold.

Based on aggregated 13F filings for Q2 2025.