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2,819 hedge funds and large institutions have $119B invested in Amgen in 2025 Q3 according to their latest regulatory filings, with 144 funds opening new positions, 1,123 increasing their positions, 1,153 reducing their positions, and 133 closing their positions.

New
Increased
Maintained
Reduced
Closed

8% more first-time investments, than exits

New positions opened: 144 | Existing positions closed: 133

8% more call options, than puts

Call options by funds: $1.88B | Put options by funds: $1.74B

1% less capital invested

Capital invested by funds: $121B → $119B (-$1.21B)

3% less repeat investments, than reductions

Existing positions increased: 1,123 | Existing positions reduced: 1,153

1% less funds holding

Funds holding: 2,8512,819 (-32)

1.78% less ownership

Funds ownership: 80.37%78.59% (-1.8%)

28% less funds holding in top 10

Funds holding in top 10: 4029 (-11)

Holders
2,819
Holders Change
-32
Holders Change %
-1.12%
% of All Funds
36.99%
Holding in Top 10
29
Holding in Top 10 Change
-11
Holding in Top 10 Change %
-27.5%
% of All Funds
0.38%
New
144
Increased
1,123
Reduced
1,153
Closed
133
Calls
$1.88B
Puts
$1.74B
Net Calls
+$135M
Net Calls Change
+$414M
Name Holding Trade Value Shares
Change
Change in
Stake
BFF
2176
Byrne Financial Freedom
Massachusetts
$359K +$369K +1,274 New
LBC
2177
Leigh Baldwin & Co
New York
$359K +$3.48K +12 +1%
HWM
2178
Horizon Wealth Management
Illinois
$357K +$1.74K +6 +0.5%
3IP
2179
3Chopt Investment Partners
Virginia
$357K -$38.9K -134 -10%
GJWM
2180
Gilliland Jeter Wealth Management
Arkansas
$356K -$33.6K -116 -8%
KW
2181
Keyvantage Wealth
Pennsylvania
$355K -$3.19K -11 -0.9%
KWMG
2182
King Wealth Management Group
Florida
$355K +$870 +3 +0.2%
4WM
2183
44 Wealth Management
Oregon
$355K
OCBCO
2184
Oversea-Chinese Banking Corp (OCBC)
Singapore
$354K
THCM
2185
Taylor Hoffman Capital Management
Virginia
$353K
IEFM
2186
IQ EQ Fund Management
Ireland
$353K +$102K +353 +39%
DAM
2187
Doheny Asset Management
California
$353K
TCOK
2188
Trust Company of Kansas
Kansas
$353K
HVIA
2189
Hudson Valley Investment Advisors
New York
$353K -$5.22K -18 -1%
SWM
2190
SFG Wealth Management
Maryland
$353K
MHR
2191
Matthew Hamilton Rosenberg
$352K -$1.45K -5 -0.4%
VP
2192
Verum Partners
North Carolina
$352K -$4.06K -14 -1%
HCWM
2193
Hidden Cove Wealth Management
Washington
$351K +$41.2K +142 +13%
CWM
2194
C2C Wealth Management
Arizona
$351K
SCM
2195
Silvant Capital Management
Georgia
$351K
CL
2196
CLG LLC
California
$350K +$1.45K +5 +0.4%
FNWM
2197
Financial Network Wealth Management
Utah
$350K +$314K +1,083 New
BRM
2198
Boston Research & Management
Massachusetts
$349K
ACA
2199
Anchor Capital Advisors
Massachusetts
$349K
GC
2200
Globeflex Capital
California
$349K

AMGN Hedge Fund Activity: Q3 2025 in Review

2,819 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q3 2025, worth a combined $119B — down 1% from $121B a quarter earlier.

Buyers outnumbered sellers: 144 funds opened new AMGN positions and 133 closed out — a net gain of 11 holders — while 1,123 added to existing stakes and 1,153 trimmed.

The largest buyer was Capital World Investors, adding an estimated $561M. The largest seller was Primecap Management, cutting an estimated $268M.

  • 2,819 institutional investors held Amgen (AMGN) as of Q3 2025, down from 2,851 in Q2 2025.
  • Funds reported $119B of Amgen stock for Q3 2025, down 1% quarter-over-quarter.
  • 144 funds opened new Amgen positions in Q3 2025 and 133 closed out, a net change of +11 holders.
  • The largest Amgen buyer in Q3 2025 was Capital World Investors, an estimated $561M added.
  • The largest Amgen seller in Q3 2025 was Primecap Management, an estimated $268M sold.

Based on aggregated 13F filings for Q3 2025.