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2,852 hedge funds and large institutions have $121B invested in Amgen in 2025 Q2 according to their latest regulatory filings, with 145 funds opening new positions, 1,230 increasing their positions, 1,096 reducing their positions, and 182 closing their positions.

New
Increased
Maintained
Reduced
Closed

12% more repeat investments, than reductions

Existing positions increased: 1,230 | Existing positions reduced: 1,096

0.54% more ownership

Funds ownership: 79.82%80.37% (+0.54%)

3% less funds holding

Funds holding: 2,9272,852 (-75)

10% less capital invested

Capital invested by funds: $133B → $121B (-$12.9B)

13% less call options, than puts

Call options by funds: $1.9B | Put options by funds: $2.17B

20% less first-time investments, than exits

New positions opened: 145 | Existing positions closed: 182

46% less funds holding in top 10

Funds holding in top 10: 7440 (-34)

Holders
2,852
Holders Change
-75
Holders Change %
-2.56%
% of All Funds
37.55%
Holding in Top 10
40
Holding in Top 10 Change
-34
Holding in Top 10 Change %
-45.95%
% of All Funds
0.53%
New
145
Increased
1,230
Reduced
1,096
Closed
182
Calls
$1.9B
Puts
$2.17B
Net Calls
-$278M
Net Calls Change
-$472M
Name Holding Trade Value Shares
Change
Change in
Stake
ECAM
2026
East Coast Asset Management
Massachusetts
$455K
S
2027
Sachetta
Massachusetts
$454K -$44.5K -157 -9%
KWM
2028
Kaydan Wealth Management
Michigan
$453K -$9.91K -35 -2%
RZH
2029
Relyea Zuckerberg Hanson
Connecticut
$452K -$28.3K -100 -6%
CAAS
2030
Capital Asset Advisory Services
Michigan
$452K -$21.5K -76 -5%
RI
2031
Ridgewood Investments
New Jersey
$450K -$26.6K -94 -6%
SOS
2032
Silver Oak Securities
Tennessee
$449K -$43.1K -152 -9%
OL
2033
Optas LLC
Texas
$448K +$68.8K +243 +18%
CH
2034
Cromwell Holdings
Wyoming
$448K
BFC
2035
Bedel Financial Consulting
Indiana
$444K
MSE
2036
MUFG Securities EMEA
United Kingdom
$444K +$450K +1,589 New
DIM
2037
Delta Investment Management
California
$443K -$19.3K -68 -4%
BT
2038
Banque Transatlantique
France
$442K -$37.4K -132 -8%
FFA
2039
Founders Financial Alliance
North Carolina
$442K +$1.7K +6 +0.4%
TBT
2040
Texas Bank & Trust
Texas
$442K
FWA
2041
FSM Wealth Advisors
Ohio
$440K +$426K +1,503 New
SFG
2042
Sovereign Financial Group
Connecticut
$440K -$6.52K -23 -1%
DWM
2043
Defined Wealth Management
Oregon
$440K -$850 -3 -0.2%
BC
2044
Bridgefront Capital
Texas
$440K +$446K +1,575 New
RIS
2045
Retirement Income Solutions
Michigan
$439K
SWA
2046
SFMG Wealth Advisors
Texas
$439K -$198K -700 -31%
IFPG
2047
Intrepid Financial Planning Group
Indiana
$438K -$39.1K -138 -8%
KA
2048
Kovack Advisors
Florida
$438K +$24.9K +88 +6%
SFA
2049
Seneca Financial Advisors
New York
$438K
FBT
2050
First Bankers Trust
Kentucky
$436K

AMGN Hedge Fund Activity: Q2 2025 in Review

2,852 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q2 2025, worth a combined $121B — down 9.7% from $133B a quarter earlier.

Sellers outnumbered buyers: 182 funds closed out of AMGN and 145 opened new positions — a net loss of 37 holders — while 1,096 trimmed existing stakes and 1,230 added.

The largest buyer was Capital International Investors, adding an estimated $1.07B. The largest seller was Primecap Management, cutting an estimated $498M.

  • 2,852 institutional investors held Amgen (AMGN) as of Q2 2025, down from 2,927 in Q1 2025.
  • Funds reported $121B of Amgen stock for Q2 2025, down 9.7% quarter-over-quarter.
  • 145 funds opened new Amgen positions in Q2 2025 and 182 closed out, a net change of -37 holders.
  • The largest Amgen buyer in Q2 2025 was Capital International Investors, an estimated $1.07B added.
  • The largest Amgen seller in Q2 2025 was Primecap Management, an estimated $498M sold.

Based on aggregated 13F filings for Q2 2025.