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2,819 hedge funds and large institutions have $119B invested in Amgen in 2025 Q3 according to their latest regulatory filings, with 144 funds opening new positions, 1,122 increasing their positions, 1,153 reducing their positions, and 133 closing their positions.

New
Increased
Maintained
Reduced
Closed

8% more first-time investments, than exits

New positions opened: 144 | Existing positions closed: 133

8% more call options, than puts

Call options by funds: $1.88B | Put options by funds: $1.74B

1% less capital invested

Capital invested by funds: $121B → $119B (-$1.21B)

3% less repeat investments, than reductions

Existing positions increased: 1,122 | Existing positions reduced: 1,153

1% less funds holding

Funds holding: 2,8512,819 (-32)

1.78% less ownership

Funds ownership: 80.37%78.59% (-1.8%)

28% less funds holding in top 10

Funds holding in top 10: 4029 (-11)

Holders
2,819
Holders Change
-32
Holders Change %
-1.12%
% of All Funds
36.99%
Holding in Top 10
29
Holding in Top 10 Change
-11
Holding in Top 10 Change %
-27.5%
% of All Funds
0.38%
New
144
Increased
1,122
Reduced
1,153
Closed
133
Calls
$1.88B
Puts
$1.74B
Net Calls
+$135M
Net Calls Change
+$414M
Name Holding Trade Value Shares
Change
Change in
Stake
M&T Bank
176
M&T Bank
New York
$48.2M -$17.6M -60,616 -26%
Bank of Nova Scotia
177
Bank of Nova Scotia
Ontario, Canada
$47.3M +$17.6M +60,794 +57%
Renaissance Technologies
178
Renaissance Technologies
New York
$47.2M -$31.9M -110,055 -40%
Comerica Bank
179
Comerica Bank
Texas
$46.7M -$3.54M -12,190 -7%
JFG
180
Jefferies Financial Group
New York
$46.6M +$9.52M +32,832 +25%
VDI
181
Vaughan David Investments
Illinois
$46.5M -$494K -1,704 -1%
William Blair & Company
182
William Blair & Company
Illinois
$45.8M -$1.35M -4,654 -3%
CA
183
Commerzbank Aktiengesellschaft
Germany
$45.7M -$47.5M -163,751 -50%
Mackenzie Financial
184
Mackenzie Financial
Ontario, Canada
$45.7M -$2.05M -7,056 -4%
SFA
185
Sequoia Financial Advisors
Ohio
$45.3M +$1.05M +3,619 +2%
Nisa Investment Advisors
186
Nisa Investment Advisors
Missouri
$45.3M +$357K +1,232 +0.8%
Skandinaviska Enskilda Banken (SEB)
187
Skandinaviska Enskilda Banken (SEB)
Sweden
$44.4M -$26.4M -91,177 -37%
Carson Wealth (CWM LLC)
188
Carson Wealth (CWM LLC)
Nebraska
$44.3M +$790K +2,723 +2%
ASRS
189
Arizona State Retirement System
Arizona
$44.3M -$18K -62 -0%
HW
190
Hancock Whitney
Mississippi
$43.2M -$517K -1,781 -1%
NW
191
NewEdge Wealth
Pennsylvania
$43.2M +$1.17M +4,018 +3%
PI
192
PineBridge Investments
New York
$43M +$9.79M +33,763 +28%
DWP
193
Daymark Wealth Partners
Ohio
$43M +$2.42M +8,334 +6%
MIM
194
MetLife Investment Management
New Jersey
$43M +$44.2M +152,356 New
WP
195
Woodline Partners
California
$42.9M -$9.14M -31,510 -17%
SO
196
STRS Ohio
Ohio
$42.8M -$3.42M -11,790 -7%
AT
197
AMF Tjänstepension
Sweden
$42.7M -$1.41M -4,847 -3%
Citadel Advisors
198
Citadel Advisors
Florida
$42.6M +$35.3M +121,735 +418%
TG
199
TCW Group
California
$42.3M -$12.4M -42,771 -22%
HPC
200
HM Payson & Co
Maine
$42M -$294K -1,014 -0.7%

AMGN Hedge Fund Activity: Q3 2025 in Review

2,819 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q3 2025, worth a combined $119B — down 1% from $121B a quarter earlier.

Buyers outnumbered sellers: 144 funds opened new AMGN positions and 133 closed out — a net gain of 11 holders — while 1,122 added to existing stakes and 1,153 trimmed.

The largest buyer was Capital World Investors, adding an estimated $561M. The largest seller was Primecap Management, cutting an estimated $268M.

  • 2,819 institutional investors held Amgen (AMGN) as of Q3 2025, down from 2,851 in Q2 2025.
  • Funds reported $119B of Amgen stock for Q3 2025, down 1% quarter-over-quarter.
  • 144 funds opened new Amgen positions in Q3 2025 and 133 closed out, a net change of +11 holders.
  • The largest Amgen buyer in Q3 2025 was Capital World Investors, an estimated $561M added.
  • The largest Amgen seller in Q3 2025 was Primecap Management, an estimated $268M sold.

Based on aggregated 13F filings for Q3 2025.