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2,819 hedge funds and large institutions have $119B invested in Amgen in 2025 Q3 according to their latest regulatory filings, with 144 funds opening new positions, 1,123 increasing their positions, 1,153 reducing their positions, and 133 closing their positions.

New
Increased
Maintained
Reduced
Closed

8% more first-time investments, than exits

New positions opened: 144 | Existing positions closed: 133

8% more call options, than puts

Call options by funds: $1.88B | Put options by funds: $1.74B

1% less capital invested

Capital invested by funds: $121B → $119B (-$1.21B)

3% less repeat investments, than reductions

Existing positions increased: 1,123 | Existing positions reduced: 1,153

1% less funds holding

Funds holding: 2,8512,819 (-32)

1.78% less ownership

Funds ownership: 80.37%78.59% (-1.8%)

28% less funds holding in top 10

Funds holding in top 10: 4029 (-11)

Holders
2,819
Holders Change
-32
Holders Change %
-1.12%
% of All Funds
36.99%
Holding in Top 10
29
Holding in Top 10 Change
-11
Holding in Top 10 Change %
-27.5%
% of All Funds
0.38%
New
144
Increased
1,123
Reduced
1,153
Closed
133
Calls
$1.88B
Puts
$1.74B
Net Calls
+$135M
Net Calls Change
+$414M
Name Holding Trade Value Shares
Change
Change in
Stake
SAA
1926
Southeast Asset Advisors
Georgia
$524K
BI
1927
Bolthouse Investments
California
$522K
FNT
1928
First Nebraska Trust
Nebraska
$522K -$189K -650 -26%
BIA
1929
Beacon Investment Advisors
Maryland
$522K +$290 +1 +0.1%
AG
1930
AmeriFlex Group
Nevada
$521K +$421K +1,452 +368%
AOWM
1931
Alpha Omega Wealth Management
Virginia
$520K -$580 -2 -0.1%
PCM
1932
Polymer Capital Management
New York
$519K +$533K +1,839 New
SI
1933
Saxon Interests
Texas
$519K +$3.48K +12 +0.7%
LBWM
1934
Left Brain Wealth Management
Illinois
$517K -$37.4K -129 -7%
KWM
1935
Keebeck Wealth Management
Illinois
$516K +$27K +93 +5%
MIA
1936
MainStreet Investment Advisors
Illinois
$515K +$53.9K +186 +11%
HFS
1937
Howard Financial Services
Texas
$515K -$10.7K -37 -2%
CCA
1938
Clearwater Capital Advisors
Illinois
$513K
FTC
1939
Farmers Trust Company
Ohio
$512K -$34.2K -118 -6%
AA
1940
Auxano Advisors
Washington
$508K -$224K -772 -30%
KC
1941
Knuff & Co
California
$508K
LIM
1942
Longfellow Investment Management
Massachusetts
$508K
PC
1943
Payne Capital
Oregon
$508K +$522K +1,800 New
SEP
1944
Southland Equity Partners
Missouri
$504K -$2.32K -8 -0.4%
DCM
1945
DGS Capital Management
New Jersey
$503K +$141K +486 +37%
OBWG
1946
Onyx Bridge Wealth Group
New York
$502K +$70.2K +242 +16%
CIC
1947
Chase Investment Counsel
Virginia
$501K -$29.6K -102 -5%
GAB
1948
German American Bancorp
Indiana
$500K -$16.5K -57 -3%
CAM
1949
Campion Asset Management
Virginia
$499K -$8.7K -30 -2%
MIM
1950
Merrion Investment Management
New Jersey
$499K -$203K -700 -28%

AMGN Hedge Fund Activity: Q3 2025 in Review

2,819 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q3 2025, worth a combined $119B — down 1% from $121B a quarter earlier.

Buyers outnumbered sellers: 144 funds opened new AMGN positions and 133 closed out — a net gain of 11 holders — while 1,123 added to existing stakes and 1,153 trimmed.

The largest buyer was Capital World Investors, adding an estimated $561M. The largest seller was Primecap Management, cutting an estimated $268M.

  • 2,819 institutional investors held Amgen (AMGN) as of Q3 2025, down from 2,851 in Q2 2025.
  • Funds reported $119B of Amgen stock for Q3 2025, down 1% quarter-over-quarter.
  • 144 funds opened new Amgen positions in Q3 2025 and 133 closed out, a net change of +11 holders.
  • The largest Amgen buyer in Q3 2025 was Capital World Investors, an estimated $561M added.
  • The largest Amgen seller in Q3 2025 was Primecap Management, an estimated $268M sold.

Based on aggregated 13F filings for Q3 2025.