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2,819 hedge funds and large institutions have $119B invested in Amgen in 2025 Q3 according to their latest regulatory filings, with 144 funds opening new positions, 1,123 increasing their positions, 1,153 reducing their positions, and 133 closing their positions.

New
Increased
Maintained
Reduced
Closed

8% more first-time investments, than exits

New positions opened: 144 | Existing positions closed: 133

8% more call options, than puts

Call options by funds: $1.88B | Put options by funds: $1.74B

1% less capital invested

Capital invested by funds: $121B → $119B (-$1.21B)

3% less repeat investments, than reductions

Existing positions increased: 1,123 | Existing positions reduced: 1,153

1% less funds holding

Funds holding: 2,8512,819 (-32)

1.78% less ownership

Funds ownership: 80.37%78.59% (-1.8%)

28% less funds holding in top 10

Funds holding in top 10: 4029 (-11)

Holders
2,819
Holders Change
-32
Holders Change %
-1.12%
% of All Funds
36.99%
Holding in Top 10
29
Holding in Top 10 Change
-11
Holding in Top 10 Change %
-27.5%
% of All Funds
0.38%
New
144
Increased
1,123
Reduced
1,153
Closed
133
Calls
$1.88B
Puts
$1.74B
Net Calls
+$135M
Net Calls Change
+$414M
Name Holding Trade Value Shares
Change
Change in
Stake
DDC
1901
DF Dent & Co
Maryland
$545K
CANC
1902
Culbertson A N & Co
Virginia
$545K +$58K +200 +12%
IA
1903
Insight Advisors
Pennsylvania
$544K -$5.8K -20 -1%
GFPC
1904
Global Financial Private Client
Florida
$544K +$258K +888 +85%
RIM
1905
RW Investment Management
Idaho
$544K -$3.48K -12 -0.6%
KA
1906
Klingman & Associates
New York
$544K +$20.9K +72 +4%
SIG
1907
Sky Investment Group
Connecticut
$543K -$14.5K -50 -3%
RF
1908
Roxbury Financial
New Jersey
$542K -$67.9K -234 -11%
AC
1909
Apella Capital
Connecticut
$540K +$14.8K +51 +3%
RPWA
1910
Regent Peak Wealth Advisors
Georgia
$539K +$554K +1,909 New
BCG
1911
Breakwater Capital Group
New Jersey
$539K +$46.7K +161 +9%
TW
1912
TritonPoint Wealth
Maryland
$537K -$8.7K -30 -2%
WI
1913
Westbourne Investments
Virginia
$537K -$7.25K -25 -1%
SI
1914
Severin Investments
Missouri
$537K +$251K +864 +83%
WIC
1915
Woodmont Investment Counsel
Tennessee
$536K -$8.7K -30 -2%
AFG
1916
Allegheny Financial Group
Pennsylvania
$536K -$1.77M -6,112 -76%
NAS
1917
Nicolet Advisory Services
Wisconsin
$536K -$40K -138 -7%
RB
1918
Rodgers Brothers
Pennsylvania
$535K -$8.7K -30 -2%
ME
1919
McIlrath & Eck
Washington
$535K -$1.45K -5 -0.3%
APW
1920
Acima Private Wealth
Virginia
$534K
CSPIA
1921
Cary Street Partners Investment Advisory
Virginia
$532K +$119K +412 +28%
SPL
1922
Smart Portfolios LLC
Washington
$532K -$24.7K -85 -4%
SPI
1923
Santori & Peters Inc
Pennsylvania
$527K
RA
1924
Ransom Advisory
Rhode Island
$526K
SSW
1925
Stone Summit Wealth
Florida
$525K +$7.54K +26 +1%

AMGN Hedge Fund Activity: Q3 2025 in Review

2,819 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q3 2025, worth a combined $119B — down 1% from $121B a quarter earlier.

Buyers outnumbered sellers: 144 funds opened new AMGN positions and 133 closed out — a net gain of 11 holders — while 1,123 added to existing stakes and 1,153 trimmed.

The largest buyer was Capital World Investors, adding an estimated $561M. The largest seller was Primecap Management, cutting an estimated $268M.

  • 2,819 institutional investors held Amgen (AMGN) as of Q3 2025, down from 2,851 in Q2 2025.
  • Funds reported $119B of Amgen stock for Q3 2025, down 1% quarter-over-quarter.
  • 144 funds opened new Amgen positions in Q3 2025 and 133 closed out, a net change of +11 holders.
  • The largest Amgen buyer in Q3 2025 was Capital World Investors, an estimated $561M added.
  • The largest Amgen seller in Q3 2025 was Primecap Management, an estimated $268M sold.

Based on aggregated 13F filings for Q3 2025.