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2,852 hedge funds and large institutions have $121B invested in Amgen in 2025 Q2 according to their latest regulatory filings, with 145 funds opening new positions, 1,230 increasing their positions, 1,096 reducing their positions, and 182 closing their positions.

New
Increased
Maintained
Reduced
Closed

12% more repeat investments, than reductions

Existing positions increased: 1,230 | Existing positions reduced: 1,096

0.54% more ownership

Funds ownership: 79.82%80.37% (+0.54%)

3% less funds holding

Funds holding: 2,9272,852 (-75)

10% less capital invested

Capital invested by funds: $133B → $121B (-$12.9B)

13% less call options, than puts

Call options by funds: $1.9B | Put options by funds: $2.17B

20% less first-time investments, than exits

New positions opened: 145 | Existing positions closed: 182

46% less funds holding in top 10

Funds holding in top 10: 7440 (-34)

Holders
2,852
Holders Change
-75
Holders Change %
-2.56%
% of All Funds
37.55%
Holding in Top 10
40
Holding in Top 10 Change
-34
Holding in Top 10 Change %
-45.95%
% of All Funds
0.53%
New
145
Increased
1,230
Reduced
1,096
Closed
182
Calls
$1.9B
Puts
$2.17B
Net Calls
-$278M
Net Calls Change
-$472M
Name Holding Trade Value Shares
Change
Change in
Stake
JSSH
151
J. Safra Sarasin Holding
$67.1M -$1.72M -6,060 -2%
Susquehanna International Group
152
Susquehanna International Group
Pennsylvania
$66.3M +$1.53M +5,411 +2%
GC
153
Guggenheim Capital
Illinois
$66.2M +$6.43M +22,706 +11%
DADC
154
D.A. Davidson & Co
Montana
$66.1M +$1.25M +4,407 +2%
SG Americas Securities
155
SG Americas Securities
New York
$66.1M +$53.5M +189,008 +395%
M&T Bank
156
M&T Bank
New York
$64.6M -$17.4M -61,355 -21%
Daiwa Securities Group
157
Daiwa Securities Group
Japan
$64.1M +$3.16M +11,147 +5%
Man Group
158
Man Group
United Kingdom
$64.1M +$9.53M +33,629 +17%
Cetera Investment Advisers
159
Cetera Investment Advisers
Illinois
$62.3M -$828K -2,923 -1%
Ohio Public Employees Retirement System (OPERS)
160
Ohio Public Employees Retirement System (OPERS)
Ohio
$61.7M -$566K -1,999 -0.9%
Focus Partners Wealth
161
Focus Partners Wealth
Massachusetts
$61.2M -$653K -2,306 -1%
FFB
162
First Financial Bankshares
Texas
$61.1M -$210K -742 -0.3%
Creative Planning
163
Creative Planning
Kansas
$60M -$2.05M -7,253 -3%
Arrowstreet Capital
164
Arrowstreet Capital
Massachusetts
$59.8M +$60.7M +214,305 New
WorldQuant Millennium Advisors
165
WorldQuant Millennium Advisors
New York
$56.7M +$47.9M +169,209 +498%
AssetMark Inc
166
AssetMark Inc
California
$56.7M +$7.63M +26,939 +15%
HPG
167
Harvest Portfolios Group
Ontario, Canada
$56.3M +$4.88M +17,241 +9%
AIM
168
Achmea Investment Management
Netherlands
$56.3M +$14.5M +51,293 +34%
MSV
169
MN Services Vermogensbeheer
Netherlands
$56.1M +$29.9M +105,600 +111%
MG
170
Marex Group
$55.9M +$5.5M +19,411 +11%
QCM
171
Quantinno Capital Management
New York
$54.7M +$5.39M +19,014 +11%
MML Investors Services
172
MML Investors Services
Massachusetts
$54.7M +$4.94M +17,437 +10%
TG
173
TCW Group
California
$53.8M -$8.19M -28,918 -13%
KK
174
KLP Kapitalforvaltning
Norway
$53.7M +$2.41M +8,500 +5%
Adage Capital Partners
175
Adage Capital Partners
Massachusetts
$52.7M -$10.5M -37,004 -16%

AMGN Hedge Fund Activity: Q2 2025 in Review

2,852 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q2 2025, worth a combined $121B — down 9.7% from $133B a quarter earlier.

Sellers outnumbered buyers: 182 funds closed out of AMGN and 145 opened new positions — a net loss of 37 holders — while 1,096 trimmed existing stakes and 1,230 added.

The largest buyer was Capital International Investors, adding an estimated $1.07B. The largest seller was Primecap Management, cutting an estimated $498M.

  • 2,852 institutional investors held Amgen (AMGN) as of Q2 2025, down from 2,927 in Q1 2025.
  • Funds reported $121B of Amgen stock for Q2 2025, down 9.7% quarter-over-quarter.
  • 145 funds opened new Amgen positions in Q2 2025 and 182 closed out, a net change of -37 holders.
  • The largest Amgen buyer in Q2 2025 was Capital International Investors, an estimated $1.07B added.
  • The largest Amgen seller in Q2 2025 was Primecap Management, an estimated $498M sold.

Based on aggregated 13F filings for Q2 2025.